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Showing metabolomics datasets: all MetaboLights and Metabolomics Workbench studies, plus GNPS-processed or metabolomics-tagged MassIVE datasets. Snapshots refresh every 24 h via background workers.

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Accession Repo Title PI / Submitter Species Instrument Keywords Date
MTBLS2 MetaboLights Comparative LC/MS-based profiling of silver nitrate-treated Arabidopsis thaliana leaves of wild-type and cyp79B2 cyp79B3 double knockout plants Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana Plant Metabolomics; Comparative LC/MS-based profiling; Pathway Elucidation; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2012-05
MTBLS6 MetaboLights Development and validation of the PyMS Mass Spectrometry software Sean OCallaghan (Metabolomics Australia) Bos taurus::reference compound PyMS; CHMO:gas chromatography-mass spectrometry; MS:data processing software; NCIT:Validation 2012-03
MTBLS4 MetaboLights High-resolution extracted ion chromatography, a new tool for metabolomics and lipidomics using a second-generation orbitrap mass spectrometer Albert Koulman (MRC-HNR) Homo sapiens EFO:metabolomic profiling; NCIT:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; open profiling; targeted metabolites; CHEBI:phospholipid 2012-02
MTBLS3 MetaboLights A metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans Reza Salek (International Agency for Research on Cancer) Caenorhabditis elegans EFO:metabolomic profiling; Free amino acid target analysis; CHMO:gas chromatography-mass spectrometry; CSEO:Lipidomics; EFO:obesity; MTBLS:targeted metabolites 2012-02
MTBLS5 MetaboLights Inorganic Carbon Limitation in Cells of the Wild Type and Photorespiratory Mutants of the Cyanobacterium Synechocystis sp. Strain PCC 6803 Joachim Kopka (Max-Planck) Synechocystis sp. PCC 6803 OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry 2015-09
MTBLS10 MetaboLights Development and validation of a liquid chromatography-electrospray ionization-time-of-flight mass spectrometry method for induced changes in Nicotiana attenuata leaves during simulated herbivory Steffen Neumann (Leibniz Institute of Plant Biochemistry) Nicotiana attenuata EFO:time series design; EFO:injury design; Plant metabolomics; OBI:correlation study objective; targeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry 2012-08
MTBLS1 MetaboLights A metabolomic study of urinary changes in type 2 diabetes in human compared to the control group Reza Salek (International Agency for Research on Cancer) Homo sapiens EFO:diabetes mellitus; EFO:metabolic syndrome; Urine global profiling; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Human Study Subject; MTBLS:untargeted metabolites 2012-02
MTBLS7 MetaboLights Metabolomic profiles in long day, after bolting, single leaf analysis, Arabidopsis thaliana Joachim Kopka (Max-Planck) Arabidopsis thaliana OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; BTO:bolting stage 2015-09
MTBLS8 MetaboLights Growth control of the eukaryote cell: a systems biology study in yeast Juan Castrillo (University of Cambridge) Saccharomyces cerevisiae untargeted metabolites; SBO:systems biology representation; endometabolome; exometabolome; CHMO:gas chromatography-mass spectrometry 2012-04
MTBLS11 MetaboLights Metabolomic profiles in long day, before bolting, single leaf analysis, Arabidopsis thaliana Joachim Kopka (Max-Planck) Arabidopsis thaliana OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; BTO:bolting stage 2015-09
MTBLS12 MetaboLights Metabolomic profiles in short day, after bolting, single leaf analysis, Arabidopsis thaliana Joachim Kopka (Max-Planck) Arabidopsis thaliana OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; BTO:bolting stage 2015-09
MTBLS13 MetaboLights Metabolomic profiles in short day, before bolting, single leaf analysis, Arabidopsis thaliana Joachim Kopka (Max-Planck) Arabidopsis thaliana OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; BTO:bolting stage 2015-09
MTBLS14 MetaboLights Metabolomic responses to long-term salt stress in related Lotus species (A) Joachim Kopka (Max-Planck) Lotus uliginosus::Lotus filicaulis::Lotus tenuis::Lotus japonicus::Lotus burttii::Lotus corniculatus::Lotus creticus OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:response to salt stress 2015-09
MTBLS15 MetaboLights Metabolomic responses to long-term salt stress in related Lotus species (B) Joachim Kopka (Max-Planck) Lotus uliginosus::Lotus filicaulis::Lotus tenuis::Lotus japonicus::Lotus burttii::Lotus corniculatus::Lotus creticus OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:response to salt stress 2015-09
MTBLS16 MetaboLights Metabolomic responses to long-term salt stress in related Lotus species (C) Joachim Kopka (Max-Planck) Lotus uliginosus::Lotus filicaulis::Lotus tenuis::Lotus japonicus::Lotus burttii::Lotus corniculatus OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:response to salt stress 2015-09
MTBLS21 MetaboLights Combining peak- and chromatogram-based retention time alignment algorithms for multiple chromatography-mass spectrometry datasets Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) Triticum aestivum CHMO:gas chromatography-mass spectrometry; EFO:metabolomic profiling; EDAM:Peak detection; multiple peak alignment; multiple alignment performance reference generation 2012-09
MTBLS18 MetaboLights Metabolic and transcriptional response of Arabidopsis thaliana wildtype and mutants to Phytophtora infestans Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana EFO:chemically induced mutation; Phytophthora infestans 90128; EFO:time series design; EFO:disease state design; EFO:infection; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:diode array detector; MTBLS:untargeted metabolites 2025-07
MTBLS20 MetaboLights Annotation of the human adult urinary metabolome and metabolite identification using ultra high performance liquid chromatography coupled to a LTQ-Orbitrap mass spectrometer Christophe Junot (CEA) Homo sapiens::blank::reference compound untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; urinary metabolome; spectral library building; MS:flow injection analysis; CHMO:tandem mass spectrometry; ror:MetaboHUB 2013-07
MTBLS19 MetaboLights LC−MS Based Serum Metabolomics for Identification of Hepatocellular Carcinoma Biomarkers in Egyptian Cohort Jinlian Wang (Georgetown university) Homo sapiens EFO:hepatocellular carcinoma; EFO:cirrhosis of liver; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2013-06
MTBLS17 MetaboLights Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis Jinlian Wang (Georgetown university) Homo sapiens EFO:hepatocellular carcinoma; EFO:cirrhosis of liver; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 1970-01
MTBLS23 MetaboLights Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation Tom Metz (Pacific Northwest National Laboratory) Mus musculus untargeted metabolites; CHMO:gas chromatography-mass spectrometry; immunometabolism; endometabolome; genome-scale modeling; metabolic network reconstruction 2012-09
MTBLS22 MetaboLights Mining for metabolic responses to long-term salt stress: a case study on Arabidopsis thaliana Col-0 (A) Joachim Kopka (Max-Planck) Arabidopsis thaliana OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:response to salt stress 2015-09
MTBLS25 MetaboLights Urine Latin Square Spike-In for testing the NMR quantification tool, MetaboQuant Matthias Klein (University of Regensburg) Homo sapiens CHMO:nuclear magnetic resonance spectroscopy; targeted metabolites; MetaboQuant; NCIT:Latin Square Study 2013-01
MTBLS24 MetaboLights Analysis of human urine reveals metabolic changes related to the development of acute kidney injury following cardiac surgery Helena Zacharias (Intitute of Functional Genomics) Homo sapiens HP:Acute kidney injury; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites 2012-10
MTBLS26 MetaboLights Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress Harald Kfeler (Medizinische Universität Graz) Mus musculus CSEO:Lipidomics; CHMO:tandem mass spectrometry; MESH:Lipid Droplets; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; MESH:Diet, High-Fat; EFO:fasting; Steatosis; Principal Component Analysis 2014-08
MTBLS27 MetaboLights Fatty acid synthesis in colorectal cancer: characterization of lipid metabolism in serum, tumour, and normal host tissues Aalim Weljie (University of Pennsylvania) blank::Homo sapiens::reference compound DOID:colorectal cancer; EFO:blood serum; CHMO:gas chromatography-mass spectrometry; NCIT:Fatty Acid Metabolism 2016-12
MTBLS32 MetaboLights Lipid mediators of inflammation in BALF 6-19 days after infection with influenza Peter Askovich (Seattle Biomedical Research Institute) Mus musculus targeted metabolites; CSEO:Lipidomics; NCIT:Bronchoalveolar Lavage Fluid; EFO:Influenza A virus; EFO:inflammatory response; CHEBI:icosanoid 2013-05
MTBLS33 MetaboLights Lipid mediators of inflammation in BALF 3-11 days after infection with influenza Peter Askovich (Seattle Biomedical Research Institute) Mus musculus targeted metabolites; CSEO:Lipidomics; NCIT:Bronchoalveolar Lavage Fluid; EFO:Influenza A virus; EFO:inflammatory response; CHEBI:icosanoid 2013-05
MTBLS34 MetaboLights Lipid mediators of inflammation in BALF 3-13 days after infection with influenza Peter Askovich (Seattle Biomedical Research Institute) Mus musculus targeted metabolites; CSEO:Lipidomics; CSEO:Bronchoalveolar Lavage Fluid; EFO:Influenza A virus; EFO:inflammatory response; CHEBI:icosanoid 2013-05
MTBLS31 MetaboLights Lipid mediators of inflammation in BALF 3-19 days after infection with influenza Peter Askovich (Seattle Biomedical Research Institute) Mus musculus targeted metabolites; CSEO:Lipidomics; NCIT:Bronchoalveolar Lavage Fluid; EFO:Influenza A virus; EFO:inflammatory response; CHEBI:icosanoid 2013-05
MTBLS35 MetaboLights Salmonella Modulates Metabolism during Growth under Conditions that Induce Expression of Virulence Genes Tom Metz (Pacific Northwest National Laboratory) Salmonella enterica untargeted metabolites; CHMO:gas chromatography-mass spectrometry; endometabolome; genome-scale modeling; SWO:Systems biology 2013-05
MTBLS37 MetaboLights Evaluation of algorithms for multiple alignment of GCxGC-MS data Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) Chlamydomonas reinhardtii untargeted metabolites; NCIT:Algorithm; CHMO:two-dimensional gas chromatography 2013-05
MTBLS29 MetaboLights Single-cell and bulk level metabolomic study of the glycolysis inhibition by 2-deoxy-D-glucose in Saccharomyces cerevisiae Alfredo Ibanez (ETHZ) Saccharomyces cerevisiae::reference compound MESH:Single-Cell Analysis; CHMO:matrix-assisted laser desorption-ionisation time-of-flight mass spectrometry; untargeted metabolites; Microarrays for Mass Spectrometry (MAMS) 2013-05
MTBLS28 MetaboLights Non-invasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer Majda Haznadar (National Cancer Institute) Homo sapiens untargeted metabolites; urine global profiling; NCIT:Tobacco Smoke; NCIT:Early Detection; DOID:lung cancer 2014-05
MTBLS38 MetaboLights Metabolite Standards for the development and validation of MassCascade Stephan Beisken (EBI) reference compound targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; MassCascade; BAO:reference compound 2014-02
MTBLS39 MetaboLights The plasticity of the grapevine berry transcriptome Silvia DalSanto (University of Verona) Vitis vinifera untargeted metabolites; JERM:Transcriptomics; CHMO:high-performance liquid chromatography-mass spectrometry 2013-11
MTBLS36 MetaboLights Metabolic differences in ripening of Solanum lycopersicum 'Ailsa Craig' and three monogenic mutants Stephan Beisken (EBI) Solanum lycopersicum::blank GO:leaf development; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MTBLS:untargeted metabolites 2014-02
MTBLS40 MetaboLights Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana Atsushi Fukushima (RIKEN) Alkane standard::Arabidopsis thaliana untargeted metabolites; EFO:metabolomic profiling; CHMO:gas chromatography-mass spectrometry 2014-03
MTBLS41 MetaboLights Mining for metabolic responses to long-term salt stress: a case study on Arabidopsis thaliana Col-0 (B) Joachim Kopka (Max-Planck) Arabidopsis thaliana OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:response to salt stress 2015-09
MTBLS42 MetaboLights Mining for metabolic responses to long-term salt stress: a case study on Arabidopsis thaliana Col-0 (C) Joachim Kopka (Max-Planck) Arabidopsis thaliana OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:response to salt stress 2015-09
MTBLS43 MetaboLights Mining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (A) Joachim Kopka (Max-Planck) Lotus japonicus OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:response to salt stress 2015-09
MTBLS44 MetaboLights Mining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (B) Joachim Kopka (Max-Planck) Lotus japonicus OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:response to salt stress 2015-09
MTBLS46 MetaboLights The cardiovascular risk of healthy individuals studied by NMR metabonomics of plasma samples Leonardo Tenori (CERM) Homo sapiens untargeted metabolites; EFO:cardiovascular disease; CHMO:nuclear magnetic resonance spectroscopy; EFO:atherosclerosis; NCIT:Oxidative Stress 2015-03
MTBLS45 MetaboLights Metabolomic correlation-network modules in Arabidopsis based on a graph-clustering approach Atsushi Fukushima (RIKEN) Alkane standard::Arabidopsis thaliana untargeted metabolites; EFO:metabolomic profiling; CHMO:gas chromatography-mass spectrometry; NCIT:Principal Component Analysis 2014-03
MTBLS48 MetaboLights Evaluation of the toxic effects of municipal wastewater effluent on mice using omic approaches Yan Zhang (Nanjing University) Mus musculus EFO:metabolomic profiling; municipal effluent; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites 2018-10
MTBLS49 MetaboLights Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei Darren Creek (Monash University) blank::Trypanosoma brucei CRISP:drug screening/evaluation; BTO:culture medium; CHMO:liquid chromatography-mass spectrometry; untargeted metabolites 2015-05
MTBLS54 MetaboLights Mining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (C) Joachim Kopka (Max-Planck) Lotus japonicus OBI:intervention design; OBI:stimulus or stress design; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:response to salt stress 2015-09
MTBLS47 MetaboLights Metabolomic Characterization of Knock-Out Mutants in Arabidopsis - Development of a Metabolite Profiling Database for Knock-Out Mutants in Arabidopsis (MeKO) Atsushi Fukushima (RIKEN) Alkane standard::Arabidopsis thaliana untargeted metabolites; EFO:metabolomic profiling; CHMO:gas chromatography-mass spectrometry 2014-03
MTBLS56 MetaboLights Quantitative metabolic profiles of tomato flesh and seeds during fruit development: complementary analysis with ANN and PCA (NMR data) Daniel Jacob (INRA Bordeaux) Solanum lycopersicum untargeted metabolites; PO:whole plant development stage; EFO:portion of plant tissue; CHMO:nuclear magnetic resonance spectroscopy; EFO:metabolomic profiling; ror:MetaboHUB 2013-09
MTBLS57 MetaboLights Enhancement of oxidative and drought tolerance in Arabidopsis by overaccumulation of antioxidant flavonoids Ryo Nakabayashi (RIKEN CSRS) Arabidopsis thaliana untargeted metabolites; JERM:Transcriptomics; SNOMEDCT:Stress tolerance; CHEBI:flavonol; CHEBI:anthocyanin; CHMO:ultra-performance liquid chromatography-mass spectrometry 2013-12
MTBLS55 MetaboLights The influence of storage on the “chemical age” of red wines Panagiotis Arapitsas (Fondazione Edmund Mach) Vitis vinifera untargeted metabolites; MESH:Food Quality; Sangiovese; MESH:Food Storage; CHMO:ultra-performance liquid chromatography-mass spectrometry 2014-02
MTBLS52 MetaboLights Profiles of phenolic secondary metabolites in plants of barley (Hordeum vulgare L.) Anna Piasecka (Institut of Plant Genetics, Polish Academy of Sciences) Hordeum vulgare PTO:drought tolerance; OBCS:multivariate analysis; CHMO:ultra high performance liquid chromatography; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2014-11
MTBLS58 MetaboLights Metabolite annotation of rat epididymis with High-resolution imaging mass spectrometry Regis Lavigne ( Protim – Irset – Inserm U1085 – University of Rennes) Rattus norvegicus untargeted metabolites; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; MTBLS:MetaSpace; EFO:infertility 2018-05
MTBLS59 MetaboLights A benchmark spike-in data set for biomarker identification in metabolomics Pietro Franceschi (Computational Biology Unit - Fondazione Edmund Mach) Malus domestica::reference compound NIFSTD:Benchmarking dataset; Targeted metabolites; EFO:metabolomic profiling; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:spiking 2013-10
MTBLS61 MetaboLights LC-MS metabolic profiling of mouse plasma and cell culture medium in relation to ABCC6 expression Robert Jansen (Weill Cornell Medicine) Homo sapiens::Mus musculus EFO:Pseudoxanthoma elasticum; EFO:metabolomic profiling; NCIT:Multidrug Resistance-Associated Protein 6; NCIT:ABCC6 Gene; Untargeted metabolites 2013-11
MTBLS67 MetaboLights Metabolomic Analysis of Fission Yeast at the Onset of Nitrogen Starvation Tomas Pluskal (Whitehead Institute for Biomedical Research) Schizosaccharomyces pombe EFO:metabolomic profiling; GO:cellular response to nitrogen starvation; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2013-11
MTBLS62 MetaboLights A large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (UPLC-MS HILIC POS assay) Arvind Subbaraj (AgResearch Ltd.) blank::Lolium perenne CHMO:hydrophilic interaction chromatography; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-03
MTBLS63 MetaboLights A large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (UPLC-MS HILIC NEG assay) Arvind Subbaraj (AgResearch Ltd.) blank::Lolium perenne CHMO:hydrophilic interaction chromatography; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-03
MTBLS72 MetaboLights Plasma Lipidomics Identifies Anticedent Memory Impairment in Older Adults Robert Padilla (Georgetown University) Homo sapiens NCIT:Lipidomics; EFO:Alzheimer's disease; CHEBI:biomarker; CHMO:ultra-performance liquid chromatography-mass spectrometry; Biocrates; Targeted metabolites; Untargeted metabolites; CHMO:tandem mass spectrometry; MS:flow injection analysis; LOINC:Cognitive Status, Mood and Pain:-:Pt:^Patient:- 2014-03
MTBLS69 MetaboLights Extracts from sweet sorghum (Sorghum bicolor), a feedstock for biorefining, suppressed proliferation and elevated apoptosis in human colon cancer stem cells via suppression of Wnt/beta-catenin signaling pathway Aaron Massey (Colorado State University) Sorghum bicolor EFO:metabolomic profiling; RCD:Phenolics; Untargeted metabolites; EFO:colorectal cancer; EFO:stem cell; CHMO:ultra-performance liquid chromatography-mass spectrometry 2014-05
MTBLS64 MetaboLights A large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (UPLC-MS C18 reverse phase POS assay) Arvind Subbaraj (AgResearch Ltd.) blank::Lolium perenne CHMO:reversed-phase chromatography; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-03
MTBLS65 MetaboLights A large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (UPLC-MS C18 reverse phase NEG assay) Arvind Subbaraj (AgResearch Ltd.) blank::Lolium perenne CHMO:reversed-phase chromatography; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-03
MTBLS71 MetaboLights A statistical analysis of the effects of urease pre-treatment on the measurement of the urinary metabolome by gas chromatography–mass spectrometry Tom Metz (Pacific Northwest National Laboratory) Homo sapiens Untargeted metabolites; CHMO:gas chromatography-mass spectrometry; BTO:urine; NCIT:Statistics; urease pre-treatment 2014-05
MTBLS75 MetaboLights Phototrophic biofilm assembly in microbial-mat-derived unicyanobacterial consortia: model systems for the study of autotroph-heterotroph interactions Tom Metz (Pacific Northwest National Laboratory) Cyanobacteria CCON:species diversity; EFO:metabolomic profiling; CHMO:confocal microscopy; BAO:real-time PCR; BIOMODELS:multi-species biofilm formation; MESH:Phototrophic Processes; ENVO:microbial mat; CCON:community dynamics; Untargeted metabolites; CHMO:gas chromatography-mass spectrometry 2014-06
MTBLS73 MetaboLights Metabolic differences in ripening of Solanum lycopersicum 'Ailsa Craig' and three monogenic mutants (alternative assay to MTBLS36) Mark Earll (Syngenta) Solanum lycopersicum::blank::reference compound Plant Metabolomics; EFO:metabolomic profiling; Untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2017-10
MTBLS74 MetaboLights Experiment design beyond gut feeling: statistical tests and power to detect differential metabolites in mass spectrometry data Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana EFO:replicate design; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:time-of-flight mass spectrometry 2014-11
MTBLS68 MetaboLights A large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (UPLC-MS C1 reverse phase NEG assay) Arvind Subbaraj (AgResearch Ltd.) blank::Lolium perenne CHMO:reversed-phase chromatography; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; NCIT:Lipidomics 2019-03
MTBLS77 MetaboLights Impacts of the Callipyge mutation on ovine plasma metabolites Juan Li (CSIRO Animal, Food and Health Sciences) Ovis aries EFO:metabolomic profiling; Callipyge mutation; CHMO:nuclear magnetic resonance spectroscopy; EFO:hypertrophy; untargeted metabolites; MESH:Multivariate Analysis; CHMO:two-dimensional 1H nuclear magnetic resonance spectroscopy 2015-01
MTBLS66 MetaboLights A large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (UPLC-MS C1 reverse phase POS and GC-MS FAME assays) Arvind Subbaraj (AgResearch Ltd.) Blank::blank::Lolium perenne CHMO:reversed-phase chromatography; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; NCIT:Lipidomics; CHEBI:fatty acid methyl ester; CHMO:gas chromatography-mass spectrometry; targeted metabolites 2019-03
MTBLS78 MetaboLights SpaceM reveals metabolic states of single cells Luca Rappez (EMBL Barcelona) Homo sapiens::blank sample::Mus musculus::reference compound GENEPIO:single cell; BTO:coculture; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:non-alcoholic steatohepatitis; EFO:non-alcoholic fatty liver disease; OMIT:Hepatocytes; GO:segmentation; CHMO:light microscopy; NCIT:Image Registration; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; MTBLS:MetaSpace 2021-05
MTBLS81 MetaboLights The impact of genetic stress by ATGL deficiency on the lipidome of lipid droplets from murine hepatocytes Harald Kfeler (Medizinische Universität Graz) Mus musculus CSEO:Lipidomics; CHMO:tandem mass spectrometry; ATGL-KO mouse; MESH:Lipid Droplets; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:fasting; Steatosis 2014-08
MTBLS85 MetaboLights High-throughput carotenoid profiling using multivariate curve resolution (Stability of isoprenoids in grape extract) Ron Wehrens (Wageningen University & Research) Vitis vinifera::reference compound CHEBI:isoprenoid; Multivariate Curve Resolution; CHMO:diode array detector; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2014-07
MTBLS79 MetaboLights Direct infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control Ralf Weber (University of Birmingham) Bos taurus::blank::Ovis aries::Bos taurus/NCBITAXON:Ovis aries Direct infusion mass spectrometry; Assay data processing method; NCIT:Quality Control; Signal processing; Batch correction; Relative standard deviation; NCIT:Reproducibility; Data processing workflow 2022-05
MTBLS87 MetaboLights Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction) Romanas Chaleckis (Nagoya City University) Homo sapiens::Schizosaccharomyces pombe blood metabolome; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2014-07
MTBLS88 MetaboLights Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions) Romanas Chaleckis (Nagoya City University) Homo sapiens blood metabolome; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2014-07
MTBLS86 MetaboLights Metabolite profiling in LC-DAD using multivariate curve resolution: the alsace package in R Ron Wehrens (Wageningen University & Research) reference compound::Manihot esculenta untargeted metabolites; CHEBI:carotenoid; CHMO:diode array detector; CHMO:ultra-performance liquid chromatography-mass spectrometry; Multivariate Curve Resolution 2014-07
MTBLS91 MetaboLights The metabolic response of marine copepods to environmental warming and ocean acidification in the absence of food Ulf Sommer (University of Birmingham) blank::Calanus CSEO:Lipidomics; Direct Infusion Mass Spectrometry; MESH:Multivariate Analysis; untargeted metabolites 2015-10
MTBLS95 MetaboLights Decreased abundance of type III secretion systeminducing signals in Arabidopsis mkp1 enhances resistance against Pseudomonas syringae Tom Metz (Pacific Northwest National Laboratory) Arabidopsis thaliana CHMO:gas chromatography-mass spectrometry; NCBITAXON:Pseudomonas syringae pv. tomato str. DC3000; GO:type III protein secretion system complex; GO:MAPK phosphatase export from nucleus; untargeted metabolites; MESH:avrPto protein, Pseudomonas syringae 2014-06
MTBLS92 MetaboLights Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients Mika Hilvo (VTT Technical Research Centre of Finland) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; CSEO:Lipidomics; DOID:breast cancer; NCIT:Chemotherapy; untargeted metabolites 2014-06
MTBLS96 MetaboLights A Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection Tom Metz (Pacific Northwest National Laboratory) Mus musculus IDO:pathogen host; AURA:Opportunistic-Pathogen; untargeted metabolites; ADW:Commensal species; SNMI:Salmonella typhimurium; CHMO:gas chromatography-mass spectrometry 2014-06
MTBLS98 MetaboLights A female gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite Simon Brown (University of Wollongong) Homo sapiens/NCBITAXON:Plasmodium falciparum::blank::Homo sapiens EFO:malaria; parasite development; untargeted metabolites; Direct Infusion Mass Spectrometry; CSEO:Lipidomics 2016-09
MTBLS94 MetaboLights PROMIS, global analysis of PROtein-Metabolite Interactions using Size separation in Arabidopsis thaliana Michal Gorka (Max Planck Institute for Molecular Plant Physiology) Arabidopsis thaliana untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; ligand-binding protein; NCIT:Protein-Protein Interaction; protein-small molecule interaction; NCIT:Proteomics; size exclusion chromatography; EDAM:Systems biology 2018-07
MTBLS90 MetaboLights Large-scale non-targeted serum metabolomics in the Prospective Investigation of the Vasculature in Uppsala Seniors Andrea Ganna (Karolinska Institutet) Homo sapiens NCIT:Cohort Study; NCIT:Population Based Study; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2014-08
MTBLS89 MetaboLights The HuMet Repository: Watching human metabolism at work Karsten Suhre (Weill Cornell Medicine - Qatar) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolomics; Human challenge study; MTBLS:Metabolon; CHMO:tandem mass spectrometry 2024-07
MTBLS100 MetaboLights The Human Saliva Metabolome Zerihun Dame (University of Alberta) Homo sapiens Biofluid; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites 2015-09
MTBLS99 MetaboLights LCMS analysis of seven apple varieties with a leaking chromatographic column Ron Wehrens (Wageningen University & Research) Malus domestica CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2015-06
MTBLS102 MetaboLights Comparative analysis of the adaptation of Staphylococcus aureus to internalization by different types of human non-professional phagocytic host cells (NMR assay) Kristin Surmann (Functional Genomics, University Greifswald) Homo sapiens/NCBITAXON:Staphylococcus aureus EFO:cell line; EFO:infection; MESH:Host-Pathogen Interactions; NCIT:Proteomics; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites 2015-07
MTBLS104 MetaboLights NMR based metabolomics study of Y2 receptor activation by neuropeptide Y in the SK-N-BE2 human neuroblastoma cell line Bo Wang (Miami University) Homo sapiens untargeted metabolites; EFO:neuroblastoma; MESH:neuropeptide Y2 receptor; EFO:cancer; PDQ:brain tumor; MESH:BIIE 0246; SK-N-BE2; CHMO:nuclear magnetic resonance spectroscopy 2014-10
MTBLS103 MetaboLights Metabolomics reveals impaired maturation of HDL particles in adolescents with hyperinsulinaemic androgen excess Sara Samino (URV-CIBERDEM) Homo sapiens untargeted metabolomics; targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:nuclear magnetic resonance spectroscopy; predictive markers; NCIT:Type 2 Diabetes Mellitus 2015-04
MTBLS93 MetaboLights Large-scale non-targeted serum metabolomics in the Swedish Twin Registry Andrea Ganna (Karolinska Institutet) Homo sapiens NCIT:Cohort Study; NCIT:Population Based Study; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Twin; untargeted metabolites 2014-08
MTBLS107 MetaboLights A metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (Zeaxanthin metabolism) Lieven vanMeulebroek (Ghent University Laboratory for Chemical Analysis) Solanum lycopersicum CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:plant hormone; CHEBI:carotenoid; Untargeted metabolites; Targeted metabolites 2014-08
MTBLS108 MetaboLights A metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (Lutein Metabolism) Lieven vanMeulebroek (Ghent University Laboratory for Chemical Analysis) Solanum lycopersicum CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:plant hormone; CHEBI:carotenoid; Untargeted metabolites; Targeted metabolites 2014-08
MTBLS106 MetaboLights Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis Dimitri Scherbakov (Institute of Medical Microbiology, University of Zürich) Homo sapiens transcriptomics; MTBLS:untargeted metabolites; unfolded protein response; chronic mistranslation; protein misfolding; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; IOBC:metabolon 2019-09
MTBLS109 MetaboLights A metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (alpha-carotene metabolism) Lieven vanMeulebroek (Ghent University Laboratory for Chemical Analysis) Solanum lycopersicum CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:plant hormone; CHEBI:carotenoid; Untargeted metabolites; Targeted metabolites 2014-08
MTBLS105 MetaboLights GC-MS Based Plasma Metabolomics for Identification of Candidate Biomarkers for Hepatocellular Carcinoma in Egyptian Cohort Habtom Ressom (Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center) Homo sapiens CHMO:gas chromatography-mass spectrometry; EFO:hepatocellular carcinoma; EFO:cirrhosis of liver; EFO:biomarker; targeted metabolites; untargeted metabolites 2015-08
MTBLS110 MetaboLights A metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (beta-carotene) Lieven vanMeulebroek (Ghent University Laboratory for Chemical Analysis) Solanum lycopersicum CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:plant hormone; CHEBI:carotenoid; Untargeted metabolites; targeted metabolites 2014-08
MTBLS111 MetaboLights A metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (Lycopene metabolism) Lieven vanMeulebroek (Ghent University Laboratory for Chemical Analysis) Solanum lycopersicum CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:plant hormone; CHEBI:carotenoid; Untargeted metabolites; Targeted metabolites 2014-08
MTBLS114 MetaboLights Nuclear Magnetic Resonance-Based Blood Metabolic Profiles of Rats Exposed to Short-Term Caloric Restriction Gustav Nestor (Swedish University of Agricultural Sciences) Rattus norvegicus untargeted metabolites; MESH:Caloric Restriction; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Exogenous Obesity 2014-09
MTBLS118 MetaboLights A Metabolic Profiling Strategy for the Dissection of Plant Defense against Fungal Pathogens (GC-MS assay) Konstantinos Aliferis (McGill) Glycine max/NCBITAXON:Rhizoctonia solani::Glycine max Plant metabolomics; CHMO:gas chromatography-mass spectrometry; MESH:Host-Pathogen Interactions; untargeted metabolites 2014-11
MTBLS117 MetaboLights A Metabolic Profiling Strategy for the Dissection of Plant Defense against Fungal Pathogens (DI-MS assays) Konstantinos Aliferis (McGill) Glycine max::Glycine max/NCBITAXON:Rhizoctonia solani Plant metabolomics; MESH:Host-Pathogen Interactions; CHMO:tandem mass spectrometry; Direct Infusion Mass Spectrometry; untargeted metabolites 2014-11
MTBLS116 MetaboLights Application of 1H-NMR Metabolomic Profiling for Reef-Building Corals Emilia Sogin (Hawaii Institute of Marine Biology ) Montipora aequituberculata::Seriatopora hystrix::Porites compressa::Pocillopora damicornis::Porites lobata EFO:metabolomic profiling; ENVO:coral reef; CHMO:nuclear magnetic resonance spectroscopy; OBI:species comparison design; sample variability; CHMO:spiking; untargeted metabolites 2014-11
MTBLS113 MetaboLights Wax ester and lipophilic compound profiling of Euglena gracilis by gas chromatography-mass spectrometry: toward understanding of wax ester fermentation under hypoxia Takeshi Furuhashi (RIKEN CSRS) Euglena gracilis::reference compound EFO:metabolomic profiling; CHEBI:wax ester; untargeted metabolites; NCIT:Hypoxia; CHMO:gas chromatography-mass spectrometry 2014-09
MTBLS112 MetaboLights GC-MS based targeted metabolic profiling identifies changes in the wheat metabolome following deoxynivalenol treatment Benedikt Warth (Univ. of Nat. Resources and Life Sciences Vienna (BOKU)) Triticum aestivum EFO:metabolomic profiling; targeted metabolites; CHMO:gas chromatography-mass spectrometry; MESH:Host-Pathogen Interactions; CHEBI:Vomitoxin; CO-WHEAT:scab; CHEBI:phenylpropanoid 2014-10
MTBLS120 MetaboLights Metabolomic Discrimination of Near Isogenic Low and High Phytate Soybean Seeds Richard Helm (Virginia Tech) Glycine max SOY:Seed phytate content; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:hydrophilic interaction chromatography; untargeted metabolites 2016-02
MTBLS119 MetaboLights Effect of NAC154 transcription factor overexpression on the field grown poplar stem wood metabolome Richard Helm (Virginia Tech) Populus tremula x Populus alba CHMO:ultra-performance liquid chromatography-mass spectrometry; MESH:Transcription Factors; CHMO:hydrophilic interaction chromatography; untargeted metabolites 2015-01
MTBLS121 MetaboLights Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system Gregoire Chevalier (Institut Pasteur) Mus musculus CHMO:high-performance liquid chromatography; targeted metabolomics; NCBITAXON:Microbiota; NBO:depressive disorder; PW:endocannabinoid signaling pathway 2021-01
MTBLS128 MetaboLights Comparative LC/MS-based profiling of L-arginine producing, canavanine resistant Corynebacterium glutamicum strain ATCC 21831 and type strain ATCC 13032 Frederik Walter (CeBiTec, Bielefeld University) blank::Corynebacterium glutamicum CHMO:high-performance liquid chromatography-mass spectrometry; CHEBI:arginine; CHMO:isotopic labelling; CHMO:isotope ratio mass spectrometry; targeted metabolites 2015-10
MTBLS127 MetaboLights Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts) Romanas Chaleckis (Nagoya City University) Mus musculus::Homo sapiens untargeted metabolites; NCIT:Resveratrol; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; EFO:cell line 1970-01
MTBLS125 MetaboLights Distribution of RESV and its metabolite peaks in mouse tissues after oral and skin administration Romanas Chaleckis (Nagoya City University) Mus musculus untargeted metabolites; NCIT:Resveratrol; OBI:oral administration; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; skin administration 2014-12
MTBLS129 MetaboLights Coordinate Regulation of Metabolite Glycosylation and Stress Hormone Biosynthesis by TT8 in Arabidopsis Shivshankar Umashankar (National University of Singapore) Arabidopsis thaliana EDAM:Transcriptomics; CHEBI:flavonoids; EFO:glycosylation; MESH:Secondary Metabolism; CHEBI:jasmonic acid; EFO:response to stress; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2016-10
MTBLS126 MetaboLights Absorption efficiency of RESV through mouse skin using 3 bases in different tissues Romanas Chaleckis (Nagoya City University) Mus musculus untargeted metabolites; NCIT:Resveratrol; skin administration; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry 2014-12
MTBLS123 MetaboLights Identification of Biomarkers using Metabolomics in Porcine Hemorrhagic Shock Charles Determan (University of Minnesota) Sus scrofa domesticus NCIT:Hemorrhagic Shock; CHMO:nuclear magnetic resonance spectroscopy; EFO:cell culture; targeted metabolites 2015-01
MTBLS133 MetaboLights Absolute quantification of metabolites in tomato fruit extracts by fast 2D NMR (Calibration Standard 500 MHz samples) Daniel Jacob (INRA Bordeaux) reference compound targeted metabolites; COSY; CHMO:two-dimensional 1H nuclear magnetic resonance spectroscopy; ror:MetaboHUB 2015-11
MTBLS131 MetaboLights Absolute quantification of metabolites in tomato fruit extracts by fast 2D NMR (Tomato 500 MHz samples) Daniel Jacob (INRA Bordeaux) Solanum lycopersicum targeted metabolites; COSY; CHMO:two-dimensional 1H nuclear magnetic resonance spectroscopy; ror:MetaboHUB 2015-01
MTBLS132 MetaboLights Absolute quantification of metabolites in tomato fruit extracts by fast 2D NMR (Tomato 700 MHz samples) Daniel Jacob (INRA Bordeaux) Solanum lycopersicum targeted metabolites; COSY; CHMO:two-dimensional 1H nuclear magnetic resonance spectroscopy; ror:MetaboHUB 2015-11
MTBLS134 MetaboLights Absolute quantification of metabolites in tomato fruit extracts by fast 2D NMR (Calibration Standard 700 MHz samples) Daniel Jacob (INRA Bordeaux) reference compound targeted metabolites; COSY; CHMO:two-dimensional 1H nuclear magnetic resonance spectroscopy; ror:MetaboHUB 2015-11
MTBLS124 MetaboLights Large-scale non-targeted plasma metabolomics in the Uppsala Longitudinal Study of Adult Men Andrea Ganna (Karolinska Institutet) Homo sapiens NCIT:Cohort Study; NCIT:Population Based Study; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2015-03
MTBLS137 MetaboLights MetaDB a Data Processing Workflow in Untargeted MS-Based Metabolomics Experiments Panagiotis Arapitsas (Fondazione Edmund Mach) Vitis vinifera untargeted metabolites; Training Dataset; OBI:software pipeline; CHMO:ultra-performance liquid chromatography-mass spectrometry 2014-11
MTBLS140 MetaboLights Metabolome analysis via an HPLC-ESI-MS-based experimental and computational pipeline for chronic nephron toxicity profiling Marc Rurik (University of Tuebingen) Homo sapiens::reference compound untargeted metabolites; NCIT:Toxicity; CHMO:high-performance liquid chromatography-mass spectrometry; EFO:cell line; CHEBI:chloroacetaldehyde 2015-09
MTBLS135 MetaboLights High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program Massimo Loda (dana-Farber cancer institute) Mus musculus Fat; CHMO:tandem mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon 2019-08
MTBLS144 MetaboLights Dissolved organic matter produced by Thalassiosira pseudonana Krista Longnecker (Woods Hole Oceanographic Institution) Thalassiosira pseudonana ADW:Phytoplankton; MESH:Carbon Cycle; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; CHMO:liquid chromatography-mass spectrometry; untargeted metabolites 2014-12
MTBLS142 MetaboLights Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research Mehdi BENIDDIR (Université Paris-Sud-Faculty of pharmacy-BioCIS) reference compound CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Database; NCIT:Natural Product; MS:ms-ms search; CHEBI:monoterpene alkaloid; CHEBI:indole skeleton 2018-12
MTBLS138 MetaboLights Multi-omics phenotyping of the gut-liver axis reveals metabolic perturbations from a low-dose pesticide mixture in rats Robin Mesnage (Kings College London) Rattus norvegicus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; PECO:Glyphosate; CHMO:tandem mass spectrometry; IOBC:metabolon 2020-11
MTBLS145 MetaboLights Physiological and Molecular Dissection of Daily Variance in Exercise Capacity Jonathan Sobel (Weizmann Institute) Mus musculus NCIT:Exercise; EFO:circadian rhythm; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; IOBC:metabolon 2019-04
MTBLS143 MetaboLights Comprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice Sam Ansari (PMI R&D) Mus musculus CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Tobacco Smoke; NCIT:Cigarette Smoking; CSEO:Modified Risk Tobacco Product; NCIT:Mouse Model; NCIT:Chronic Obstructive Pulmonary Disease; MTBLS:Shotgun lipidomics; targeted metabolites; untargeted metabolites; CHEBI:icosanoid 2015-11
MTBLS146 MetaboLights Pregnancy-Induced Metabolic Phenotype Variations in Maternal Plasma Robert Davidson (University of Birmingham) Homo sapiens EFO:pregnancy; CHMO:high-performance liquid chromatography-mass spectrometry; BTO:blood plasma; MTBLS:Shotgun lipidomics; carnitine profiling; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; MS:flow injection analysis 2015-03
MTBLS147 MetaboLights Probabilistic networks of blood metabolites in healthy subjects as indicators of latent cardiovascular risk Claudio Santucci (CERM) Homo sapiens CHMO:nuclear magnetic resonance spectroscopy; EFO:cardiovascular disease; targeted metabolites 2015-01
MTBLS136 MetaboLights Serum metabolomic profiles associated with postmenopausal hormone use Victoria Stevens (American Cancer Society) Homo sapiens NCIT:Menopause; NCIT:Hormone; CHEBI:Estrogen; CHEBI:Progestin; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MTBLS:untargeted metabolites; MTBLS:metabolon 2019-06
MTBLS148 MetaboLights Impact of collection conditions on the metabolite content of human urine samples as analyzed by liquid chromatography coupled to mass spectrometry and nuclear magnetic resonance spectroscopy (LC-MS assay) EtienneA Thevenot (Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA)) Homo sapiens untargeted metabolites; EFO:urine; CHMO:ultra-performance liquid chromatography-mass spectrometry; ror:MetaboHUB 2014-12
MTBLS151 MetaboLights Quantitative 1H NMR metabolome profiling of Thai Jasmine rice (Oryza sativa) reveals primary metabolic response during brown planthopper infestation umaporn uawisetwathana (National Center for Genetic Engineering and Biotechnology) Oryza sativa untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; Chemometrics; NCBITAXON:Nilaparvata lugens 2016-11
MTBLS150 MetaboLights Distinct metabolic responses of an ovarian cancer stem cell line Kathleen Vermeersch (Georgia Institute of Technology) Homo sapiens untargeted metabolites; NCIT:Ovarian Carcinoma; BTO:cancer stem cell; cancer metabolism; CHMO:gas chromatography-mass spectrometry; CHMO:two-dimensional gas chromatography 2021-11
MTBLS152 MetaboLights OVCAR-3 spheroid-derived cells display distinct metabolic profiles Kathleen Vermeersch (Georgia Institute of Technology) Homo sapiens untargeted metabolites; CCO:Ovarian cancer; NCIT:Cancer Stem Cell; cancer metabolism; CHMO:gas chromatography-mass spectrometry; CHMO:two-dimensional gas chromatography 2015-01
MTBLS149 MetaboLights Metabolomic assessment of acute cholestatic injuries induced by thioacetamide and by bile duct ligation, and the protective effects of Huang-Lian-Jie-Du-Decoction Junsong Wang (Center for Molecular Metabolism, Nanjing University of Science and Technology) Rattus norvegicus EFO:metabolomic profiling; NCIT:Cholestasis; CHEBI:thioacetamide; Bile duct ligation; orthogonal partial least squares discriminant analysis (OPLS-DA); NCIT:Huang Lian; Huang-Lian-Jie-Du-Decoction (HLJDD); CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites 2016-06
MTBLS154 MetaboLights Phosphorus availability regulates intracellular nucleotides in marine eukaryotic phytoplankton Krista Longnecker (Woods Hole Oceanographic Institution) Thalassiosira pseudonana ADW:Phytoplankton; MESH:Carbon Cycle; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; CHMO:liquid chromatography-mass spectrometry; targeted metabolites; untargeted metabolites 2015-01
MTBLS155 MetaboLights Release of Ecologically Relevant Metabolites by the Cyanobacterium, Synechococcus elongatus CCMP 1631 Krista Longnecker (Woods Hole Oceanographic Institution) Synechococcus elongatus ADW:Phytoplankton; MESH:Carbon Cycle; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; CHMO:liquid chromatography-mass spectrometry; targeted metabolites; untargeted metabolites 2015-01
MTBLS156 MetaboLights 1H HR-MAS NMR Based Metabolic Profiling of Cells in Response to Treatment with a Hexacationic Ruthenium Metallaprism as Potential Anticancer Drug Martina Vermathen (University of Bern) Homo sapiens untargeted metabolites; CHMO:magic angle spinning nuclear magnetic resonance spectroscopy; hexacationic ruthenium metallaprism; cancer cells 2015-01
MTBLS157 MetaboLights Evidence for quorum sensing and differential metabolite production by Ruegeria pomeroyi in response to DMSP Krista Longnecker (Woods Hole Oceanographic Institution) Ruegeria pomeroyi MESH:Carbon Cycle; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; CHMO:liquid chromatography-mass spectrometry; targeted metabolites; untargeted metabolites 2015-01
MTBLS161 MetaboLights Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients Christopher Armstrong (Bio21, University of Melbourne) Homo sapiens NCIT:Chronic Fatigue Syndrome; NCIT:Glycolysis Pathway; NCIT:Oxidative Stress; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites; ADO:Energy metabolism; CHEBI:amino acid 2015-06
MTBLS159 MetaboLights Metabolomic Profile of Diet-Induced Obesity Mice in Response to Human and Small Humanin-like Peptide 2 Treatment Pinchas Cohen (University of Southern California, Leonard Davis School of Gerontology) Mus musculus mitochondrial derived peptides; EFO:diet; EFO:obesity; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; IOBC:metabolon 2019-06
MTBLS163 MetaboLights Quantitative profiling of endocannabinoids in lipoproteins by LC–MS/MS Mesut Bilgin (MPI-CBG) reference compound::Homo sapiens CHMO:liquid chromatography-tandem mass spectrometry; CHEBI:endocannabinoid; CHEBI:lipoprotein; CSEO:Lipidomics; targeted metabolites 2015-03
MTBLS160 MetaboLights Natural variation of root exudates in Arabidopsis thaliana-linking metabolomic and genomic data Steffen Neumann (Leibniz Institute of Plant Biochemistry) blank::Arabidopsis thaliana EFO:genotype; PECO:hydroponic plant culture media; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; targeted metabolites 2017-02
MTBLS162 MetaboLights Mechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes (Human data) Xinzhu Wang (University of Cambridge) Homo sapiens::blank MESH:Lipogenesis; EFO:diabetes mellitus; Direct Infusion Mass Spectrometry; MEDDRA:Dyslipidaemia; targeted metabolites 2015-10
MTBLS158 MetaboLights Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke Bjoern Titz (Philip Morris International R&D) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Tobacco Smoke; NCIT:Cigarette; CHMO:tandem mass spectrometry; IOBC:metabolon 2020-04
MTBLS166 MetaboLights NMR- and LC–MS/MS-based urine metabolomic investigation of the subacute effects of hexabromocyclododecane in mice (NMR assay) Wentao Zhu (China Agricultural University) Mus musculus MESH:hexabromocyclododecane; untargeted metabolites; CHEBI:amino acid; CHMO:nuclear magnetic resonance spectroscopy 2015-02
MTBLS164 MetaboLights Searching for metabolic changes in urine headspace composition as an effect of strenuous walking Phil Brown (Radboud University) Homo sapiens untargeted metabolites; NCIT:Walking; NCIT:Diabetes Mellitus; CHEBI:acetic acid; CHMO:proton transfer reaction mass spectrometry; CHEBI:acetone 2016-12
MTBLS165 MetaboLights Changes in the Milk Metabolome of the Giant Panda (Ailuropoda melanoleuca) with Time after Birth – Three Phases in Early Lactation and Progressive Individual Differences Tong Zhang (Wolfson Wohl Cancer Research Centre, Glasglow University) Ailuropoda melanoleuca untargeted metabolites; SNOMEDCT:Lactation; CHMO:high-performance liquid chromatography-mass spectrometry 2015-03
MTBLS169 MetaboLights Metabolite Profiling of wildtype and overexpression Arabidopsis thaliana Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana OBI:comparative phenotypic assessment; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:time-of-flight mass spectrometry; MTBLS:untargeted metabolites 2015-09
MTBLS168 MetaboLights The metabolic background is a global player in Saccharomyces gene expression epistasis MohammadTauqeer Alam (University of Cambridge) Saccharomyces cerevisiae untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; GEXO:epistasis 2016-12
MTBLS170 MetaboLights Computational Ranking of Yerba Mate Small Molecules Based on Their Predicted Contribution to Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus Caroline Rempe (University of Tennessee) Ilex paraguariensis NCIT:Methicillin Resistant Staphylococcus aureus; CHMO:gas chromatography-mass spectrometry; OBI:metabolite profiling; untargeted metabolites 2015-03
MTBLS174 MetaboLights Multi-omic profiles of human nonalcoholic fatty liver disease tissue highlight heterogenic phenotypes Ewa Gralka (University of Florence-CERM) Homo sapiens untargeted metabolites; NCIT:Steatosis; EFO:metabolic syndrome; NCIT:Human Study Subject; Serum global profiling; CHMO:nuclear magnetic resonance spectroscopy 2015-12
MTBLS172 MetaboLights Metabolomics profiling of pre-and post-anesthesia plasma samples obtained via Ficoll separation veronica ghini (CERM) Homo sapiens untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; EFO:colorectal cancer; MESH:Anesthesia 2015-11
MTBLS176 MetaboLights Benchmark datasets for 3D MALDI- and DESI-Imaging Mass Spectrometry Janina Oetjen (University of Bremen) Homo sapiens::Bacillus subtilis and Streptomyces coelicolor::Mus musculus BAO:mass spectrometry; CHMO:desorption electrospray ionisation mass spectrometry; Matrix assisted laser desorption ionisation 2016-07
MTBLS175 MetaboLights Metabolomics-derived insights into the manipulation of terpenoid sysnthesis in Centella asiatica cells by methyl-jasmonate Fidele Tugizimana (University of Johannesburg) Centella asiatica CHMO:gas chromatography-mass spectrometry; multivariate statistics; CHEBI:(-)-methyl jasmonate; NCIT:Terpenoid Biosynthesis Pathway; untargeted metabolites; targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2015-03
MTBLS173 MetaboLights Comprehensive Metabolic Profiling of Age-Related Mitochondrial Dysfunction in the High-Fat-Fed ob/ob Mouse Heart Xinzhu Wang (University of Cambridge) Mus musculus Respiratory capacity; EFO:high fat diet; EFO:aging; EFO:obesity; CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolites 2015-11
MTBLS177 MetaboLights Metabolic responses induced by DNA damage and poly (ADP-ribose) polymerase (PARP) inhibition in MCF-7 cells Vijesh Bhute (University of Cambridge) Homo sapiens targeted metabolites; EFO:cancer; NCIT:DNA Damage; CHEBI:EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; CHMO:nuclear magnetic resonance spectroscopy 2015-08
MTBLS171 MetaboLights Assessment of automated trimethylsilyl derivatisation protocols for GC-MS-based untargeted metabolomic analysis of urine Hayley Abbiss (Murdoch University) Rattus norvegicus CHMO:gas chromatography-mass spectrometry; CHMO:trimethylsilyl derivatisation; BTO:urine; untargeted metabolites 2015-09
MTBLS178 MetaboLights The correlation of gut microbiota and serum metabolites with Sasang constitution Cho Kyoungwon (Korea Basic Science Institute (KBSI)) Homo sapiens untargeted metabolites; EFO:Sasang constitutional medicine; Multivariate statistics; CHMO:ultra-performance liquid chromatography-mass spectrometry 2015-03
MTBLS179 MetaboLights Comparative Metabolomic Sampling of Upper and Lower Airways by Four Different Methods to Identify Biochemicals That May Support Bacterial Growth John Tregoning (Imperial College London) Homo sapiens NCIT:Airway; NCIT:Bacterial Infection; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; IOBC:metabolon 2019-06
MTBLS182 MetaboLights Isotopomer analysis of MCF-7 breast cancer cell line incubated with 13C labelled glucose (GC-MS assay) Silvia Marin (Universitat de Barcelona) Homo sapiens::reference compound tracer-based metabolomics; DOID:breast cancer; isotopologue; CHMO:gas chromatography-mass spectrometry 2018-05
MTBLS181 MetaboLights How Does the Seed Pre-germinative Metabolism Fight against Imbibition Damage? Emerging Roles of Fatty Acid Cohort and Antioxidant Defence Alma Balestrazzi (University of Pavia) Medicago truncatula CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; GO:Seed germination; MTBLS:Imbibition damage; MTBLS:legume seed; NCIT:Lipidomics; metabolon; CHMO:tandem mass spectrometry; MTBLS:Antioxidant response 2019-10
MTBLS185 MetaboLights Metabolic fingerprinting reveals a novel candidate biomarker for prednisolone treatment in cattle Nathalie DeClercq (Ghent University) Bos taurus untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:prednisolone; EFO:biomarker 2017-01
MTBLS180 MetaboLights Rapid metabolic shifts occur during the transition between hunger and satiety in Drosophila melanogaster MONICA DUS (University of Michigan) Drosophila melanogaster CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MTBLS:High sucrose diet; EFO:obesity; CHMO:tandem mass spectrometry; IOBC:metabolon 2019-07
MTBLS186 MetaboLights Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes Julia Jellusova (BIOSS/Albert Ludwigs University Freiburg) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; IOBC:metabolon; NCIT:Immunoglobulin; MTBLS:Mitochondrial function 2020-04
MTBLS187 MetaboLights Diel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms Tom Metz (Pacific Northwest National Laboratory) Synechococcus sp.;NCBITAXON:Roseiflexus;NCBITAXON:Candidatus Chloracidobacterium;Candidatus Thermochlorobacter spp.;NCBITAXON:Chloroflexus CHMO:gas chromatography-mass spectrometry; ENVO:microbial mat; CHEBI:poly(hydroxyalkanoate); DRON:CETYL ESTERS WAX; untargeted metabolites; targeted metabolites; NCBITAXON:Chloroflexus 2024-02
MTBLS188 MetaboLights Supplemental data for CAMERA, an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana::blank::reference compound EFO:spike-in quality control role; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2015-05
MTBLS191 MetaboLights The use of metabolomics to monitor simultaneous changes in metabolic variables following supramaximal low volume high intensity exercise Jessica Danaher (Victoria University) Homo sapiens EFO:exercise; untargeted metabolites; CSEO:Lipidomics; NCIT:Glycolysis Pathway; high intensity excercise; CHMO:gas chromatography-mass spectrometry; low volume 2015-06
MTBLS189 MetaboLights Comparison of Two Different Astragali Radix by 1H NMR based Metabolomic Approach Zhenyu Li (Modern Research Center for Traditional Chinese Medicine of Shanxi University) Astragalus mongholicus::Mus musculus CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites; Astragali Radix; chemical differences; metabolic changes 2017-01
MTBLS194 MetaboLights Matrix Effect on Chemical Isotope Labeling and Its Implication in Metabolomic Sample Preparation for Quantitative Metabolomics Wei Han (University of Alberta) Mus musculus Matrix effect; CHMO:high-performance liquid chromatography-mass spectrometry; Chemical isotope Labeling; targeted metabolites 2015-07
MTBLS183 MetaboLights The effects of oligomycin administration and glutamine deprivation on metabolic profile of MCF7 breast cancer cell line measured using [1,2-13C2]-D-glucose and [U-13C5]-L-glutamine as tracers Silvia Marin (Universitat de Barcelona) Homo sapiens tracer-based metabolomics; DOID:breast cancer; EFO:MCF-7; isotopologue; CHMO:gas chromatography-mass spectrometry; JERM:Fluxomics; CHEBI:glutamine; CHEBI:oligomycin 2021-01
MTBLS193 MetaboLights Metabolomics approach to understand the resource partitioning in Chlorella during growth Shivshankar Umashankar (National University of Singapore) blank::Parachlorella::Chlorella::matrix Batch effects; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2016-10
MTBLS197 MetaboLights ATP-binding Cassette Sub-family C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs Robert Jansen (Weill Cornell Medicine) Mus musculus CCO:ABCC5; CHEBI:kainic acid; glutamate analogs; CHMO:high-performance liquid chromatography-mass spectrometry; glutamate conjugates; untargeted metabolites; AURA:Blood-Brain-Barrier; NCIT:Neurotoxin; GO:drug transport; GO:neurotransmitter transport; CCO:MRP5 2015-11
MTBLS196 MetaboLights Integrated omics analysis of pathogenic host responses during pandemic H1N1 influenza virus infection: the crucial role of lipid metabolism Tom Metz (Pacific Northwest National Laboratory) Mustela putorius untargeted metabolites; CHMO:gas chromatography-mass spectrometry; SWO:Systems biology; CSEO:Lipidomics; NCIT:H1N1 Influenza; CHMO:ultra-performance liquid chromatography-mass spectrometry 2016-05
MTBLS200 MetaboLights Temporal characterization of serum metabolite signatures in lung cancer patients undergoing treatment Farshad Farshidfar (University of Calgary) Homo sapiens NCIT:Clinical Study; CHMO:nuclear magnetic resonance spectroscopy; CHMO:gas chromatography-mass spectrometry; untargeted metabolies; DOID:lung cancer; NCIT:Personalized Medicine 2017-01
MTBLS203 MetaboLights Navigating natural variation in herbivory-induced secondary metabolism in coyote tobacco populations using MS/MS structural analysis Dapeng Li (Max planck institute for chemical ecology) Nicotiana attenuata untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; Natural variation; MESH:Herbivory; EFO:metabolomic profiling; NCBITAXON:Manduca sexta; CHMO:tandem mass spectrometry 2015-06
MTBLS198 MetaboLights Urinary metabolomic profiling to identify biomarkers of a flavonoid-rich and flavonoid-poor fruits and vegetables diet in adults: the FLAVURS trial Maria Ulaszewska (Fondazione Edmund Mach, Metabolomics Unit) Homo sapiens untargeted metabolites; Cardiovascular health; CHEBI:flavonoids; NCIT:Dietary Intervention; Fruit and vegetables 2017-01
MTBLS201 MetaboLights An ambient-temperature storage and stabilization device performs comparably to flash-frozen collection for stool metabolomics in infants Suchitra Hourigan (Inova Health Systems) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; resultAFR:ambient temperature; NCIT:Method Development; EFO:infant; IOBC:metabolon; CHMO:tandem mass spectrometry 2021-01
MTBLS208 MetaboLights The response of Chlamydomonas reinhardtii to nitrogen deprivation: a systems biology analysis JeongJin Park (Washington State University) Chlamydomonas reinhardtii EFO:metabolomic profiling; nitrogen deprivation; CHEBI:triglyceride; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2015-06
MTBLS206 MetaboLights The role of FYCO1-dependent autophagy in lens fiber cell differentiation. OM omgeneticsjhmiedu (The Wilmer Eye Institute Johns Hopkins University School of Medicine) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Mouse lens; IOBC:metabolon; CHMO:tandem mass spectrometry 2024-03
MTBLS207 MetaboLights Examining the effects of cigarette smoke on mouse lens through a multi OMIC approach OM omgeneticsjhmiedu (The Wilmer Eye Institute Johns Hopkins University School of Medicine) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Mouse lens; IOBC:metabolon; CHMO:tandem mass spectrometry 2024-03
MTBLS204 MetaboLights Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites (Cohort 1) David Michonneau (APHP) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Allogeneic hematopoietic stem cell transplantation; NCIT:Lipidomics; IOBC:metabolon; CHMO:tandem mass spectrometry 2019-11
MTBLS205 MetaboLights Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites (Cohort 2) David Michonneau (APHP) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Allogeneic hematopoietic stem cell transplantation; NCIT:Lipidomics; IOBC:metabolon; CHMO:tandem mass spectrometry 2019-11
MTBLS210 MetaboLights Wolbachia modulation of lipid metabolism in Aedes albopictus mosquito cells Ulf Sommer (University of Birmingham) blank::Aedes albopictus Direct Infusion Mass Spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites; CSEO:Lipidomics; CHMO:Fourier transform ion cyclotron resonance mass spectrometry 1970-01
MTBLS213 MetaboLights geoRge: A Computational Tool To Detect the Presence of Stable Isotope Labeling in LC/MS-Based Untargeted Metabolomics Sara Samino (URV-CIBERDEM) Homo sapiens untargeted metabolites; carbon tracking; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Diabetic Retinopathy 2015-09
MTBLS209 MetaboLights The measurement of spatial distribution of grape metabolites in berry tissues using LC-MS Luca Narduzzi (Fondazione Edmund Mach) Vitis targeted metabolites; grape metabolome; EFO:metabolomic profiling; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; CHMO:tandem mass spectrometry 2017-01
MTBLS212 MetaboLights Untangling the wine metabolome by combining untargeted SMPE-GCxGC-TOF-MS and sensory analysis to profile Sauvignon blanc co-fermented with seven different yeasts Margaret Whitener (Fondazione Edmund Mach) Vitis vinifera NCIT:Wine; CHMO:two-dimensional gas chromatography; CHMO:time-of-flight mass spectrometry; Sauvignon blanc; CHMO:fermentation; MTBLS:untargeted metabolites; sensory analysis; CHMO:solid-phase micro-extraction 2015-08
MTBLS214 MetaboLights Global Metabonomic and Proteomic Analysis of Human Conjunctival Epithelial Cells (IOBA-NHC) in Response to Hyperosmotic Stress Liyan Chen (Singapore Eye Research Institute) Homo sapiens EFO:hyperosmotic salinity response; untargeted metabolites; EFO:dry eye syndrome; DIAB:hyperosmolarity; osmoprotectants; EFO:response to osmotic stress; ultra-fast liquid chromatography-mass spectrometry 2015-08
MTBLS216 MetaboLights Metabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry liu jinwen (BGI) Mus musculus NCBITAXON:Toxoplasma gondii; untargeted metabolites; IDO:parasite host; CHMO:liquid chromatography-mass spectrometry 2017-01
MTBLS217 MetaboLights Global Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii liu jinwen (BGI) Mus musculus NCBITAXON:Toxoplasma gondii; untargeted metabolites; CHMO:liquid chromatography-mass spectrometry; IDO:parasite host 2017-01
MTBLS215 MetaboLights Fragmentation patterns of methyloxime-trimethylsilyl derivatives of constitutive mono- and disaccharide isomers analyzed by gas chromatography/field ionization mass spectrometry Takeshi Furuhashi (RIKEN CSRS) reference compound CHMO:field ionisation mass spectrometry; targeted metabolites; CHMO:gas chromatography-mass spectrometry 2015-12
MTBLS219 MetaboLights Deletion of glycerol channel aquaporin-9 (Aqp9) impairs long-term blood glucose control in C57BL/6 leptin receptor-deficient (db/db) obese mice Michael Rutzler (Aalborg University) blank::alkane reference::Mus musculus CHMO:gas chromatography-mass spectrometry; NCIT:Gene Knockout; EFO:obesity; untargeted metabolites 2015-09
MTBLS218 MetaboLights An untargeted metabolomics approach to characterize short-term and long-term metabolic changes after bariatric surgery Sophie Narath (JOANNEUM RESEARCH HEALTH - Institute for Biomedicine and Health Sciences Neue Stiftingtalstraße 2 A-8010 Graz) blank::Homo sapiens NCIT:Bariatric Surgery; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; MS:XCMS 2015-09
MTBLS225 MetaboLights Targeted metabolomic analysis in hepatic extracts, serum, and urine of female mice gavaged with TCDD every 4 days for 28 days Rance Nault (Michigan State University) Mus musculus CHEBI:2,3,7,8-tetrachlorodibenzodioxine; MESH:Dose-Response Relationship, Drug; targeted metabolites; MEDDRA:Hepatotoxicity; CHMO:liquid chromatography-tandem mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry 2017-02
MTBLS226 MetaboLights Metabolomics identifies the intersection of phosphoethanolamine with menaquinone- triggered apoptosis in an in vitro model of leukemia Suganthagunthalam Dhakshinamoorthy (Georgia Institute of technology) Homo sapiens CHMO:two-dimensional gas chromatography; EFO:cancer; CHMO:gas chromatography-mass spectrometry; NCIT:Apoptosis; untargeted metabolites 2015-10
MTBLS228 MetaboLights Untargeted extraction of metabolites 13C labeling profiles from time course labeling switch experiment Patrick Kiefer (Institute of Microbiology ETH Zurich) Bacillus methanolicus FIX:isotope method; nanoscale high performance liquid chromatography mass spectrometry; untargeted metabolites; DynaMet 2015-10
MTBLS220 MetaboLights Operational tolerance after hematopoietic stem cell transplantation is characterized by distinct transcriptional, phenotypic, and metabolic signatures (Cohort 1). David Michonneau (APHP) Homo sapiens NCIT:Allogeneic Hematopoietic Stem Cell Transplantation; NCIT:Immunology; NCIT:Tolerance; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Oncology; MTBLS:metabolon; CHMO:tandem mass spectrometry 2021-12
MTBLS227 MetaboLights N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression Stephanie Holst (Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands) Homo sapiens GLYCO:glycan; BTO:colorectal cancer cell line; CHMO:nanoflow high-performance liquid chromatography; CHMO:matrix-assisted laser desorption-ionisation mass spectrometry; untargeted metabolites 2017-02
MTBLS229 MetaboLights Untargeted extraction of metabolites 13C labeling profiles from time course labeling switch experiment Patrick Kiefer (Institute of Microbiology ETH Zurich) Escherichia coli FIX:isotope method; nanoscale high performance liquid chromatography mass spectrometry; untargeted metabolites; DynaMet 2015-10
MTBLS221 MetaboLights Operational tolerance after hematopoietic stem cell transplantation is characterized by distinct transcriptional, phenotypic, and metabolic signatures (Cohort 2). David Michonneau (APHP) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Allogeneic Hematopoietic Stem Cell Transplantation; NCIT:Immunology; NCIT:Tolerance; NCIT:Oncology; MTBLS:metabolon; CHMO:tandem mass spectrometry 2021-12
MTBLS234 MetaboLights Automated Label-free Quantification of Metabolites from Liquid Chromatography–Mass Spectrometry Data (Plasma) Erhan Kenar (Quantitative Biology Center Tübingen) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolites; MS:LC-MS label-free quantitation analysis 2015-12
MTBLS235 MetaboLights Automated Label-free Quantification of Metabolites from Liquid Chromatography–Mass Spectrometry Data (Simulated) Erhan Kenar (Quantitative Biology Center Tübingen) simulated data targeted metabolites; MS:LC-MS label-free quantitation analysis; liquid chromatogaphy-mass spectrometry data simulation 2015-12
MTBLS233 MetaboLights Improving global feature detectabilities through scan range splitting for untargeted metabolomics by high-performance liquid chromatography-Orbitrap mass spectrometry Marc Rurik (University of Tuebingen) blank::Homo sapiens untargeted metabolomics; Scan range splitting; CHMO:HPLC-MS 2016-06
MTBLS240 MetaboLights Maslinic acid-enriched diet decreases intestinal tumorigenesis in Apc(Min/+) mice through transcriptomic and metabolomic reprogramming Karen Atkins (University of Birmingham) Mus musculus EFO:colorectal cancer; EFO:Familial adenomatous polyposis; Apc_Min/+; CHEBI:maslinic acid; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites 2017-02
MTBLS243 MetaboLights Collagen induced arthritis in dba/1j mice associates with oxylipin changes in plasma Michael vanVliet (Leiden University) Mus musculus CHMO:reversed-phase solid-phase extraction; EFO:inflammation; targeted metabolites; EFO:arthritis; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry 2015-11
MTBLS241 MetaboLights Isotopomer analysis of MCF-7 breast cancer cell line incubated with 13C labelled glucose (NMR assay) Karen Atkins (University of Birmingham) Homo sapiens::reference compound DOID:breast cancer; tracer-based metabolomics; PLIO:isotopomer; JERM:Fluxomics; CHMO:nuclear magnetic resonance spectroscopy 2018-05
MTBLS237 MetaboLights Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals Karen Atkins (University of Birmingham) Homo sapiens untargeted metabolites; MESH:Dysbiosis; EFO:inflammatory bowel disease; EFO:ulcerative colitis; CHMO:nuclear magnetic resonance spectroscopy; EFO:Crohn's disease 2017-02
MTBLS247 MetaboLights Positional Enrichment by Proton Analysis (PEPA): a One-Dimensional 1H-NMR Approach for 13C Stable Isotope Tracer Studies in Metabolomics Maria Vinaixa (Universitat Rovira i Virgili-Yanes Lab) Homo sapiens PEPA; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites; tracer; PR:exonuclease 3'-5' domain-containing protein 2 2017-02
MTBLS239 MetaboLights Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease Karen Atkins (University of Birmingham) Homo sapiens EFO:ulcerative colitis; EFO:Crohn's disease; EFO:inflammatory bowel disease; BAO:Tumor necrosis factor; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites; NCIT:Infliximab 2022-01
MTBLS253 MetaboLights Metabolic characterization of the natural progression of chronic hepatitis B (Oxylipin assay) Michael vanVliet (Leiden University) Homo sapiens targeted metabolites; EFO:chronic hepatitis B infection; EFO:inflammation; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:solid-phase micro-extraction 2016-06
MTBLS242 MetaboLights Metabolomic fingerprint of severe obesity is dynamically affected by bariatric surgery in a procedure-dependent manner Leonardo Tenori (CERM) Homo sapiens untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; EFO:gastric bypass; MEDDRA:Sleeve gastrectomy 2017-02
MTBLS256 MetaboLights A Combined Metabolomic and Proteomic Investigation of the Effects of a Failure to Express Dystrophin in the Mouse Heart Jules Griffin (Imperial College London) Mus musculus CHMO:nuclear magnetic resonance spectroscopy; ECG:Pattern_Recognition; untargeted metabolites; EFO:Duchenne muscular dystrophy; CHEBI:taurine 2017-03
MTBLS249 MetaboLights Plasma metabolic profile in COPD patients: effects of exercise and endurance training Karen Atkins (University of Birmingham) Homo sapiens EFO:chronic obstructive pulmonary disease; targeted metabolites; Skeletal muscle dysfunction; EFO:exercise; Endurance training; CHMO:nuclear magnetic resonance spectroscopy 2017-03
MTBLS259 MetaboLights Metabolomics reveals an involvement of pantothenate for male production responding to the short-day stimulus in the water flea, Daphnia pulex Alex Gavin (University of Birmingham) solvent::blank::Daphnia pulex D.pulex WTN6; Environmental sex determination (ESD); Direct Infusion Mass Spectrometry; untargeted metabolites 2017-04
MTBLS260 MetaboLights Investigating the Mechanisms of Silver Nanoparticle Toxicity in Daphnia magna: A Multi-Omics Approach Alex Gavin (University of Birmingham) Daphnia magna CHEBI:silver nanoparticle; CHEBI:silver(0); Direct Infusion Mass Spectrometry; MS:fourier transform ion cyclotron resonance mass spectrometer; untargeted metabolites 2017-05
MTBLS263 MetaboLights Individual variability in human blood metabolites identifies age-related differences - determination of coefficients of variation for each metabolite (3 injections of same sample, 3 independent sample preparations) Romanas Chaleckis (Nagoya City University) Homo sapiens NCIT:Variation; blood metabolome; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2016-03
MTBLS265 MetaboLights Individual variability in human blood metabolites identifies age-related differences (30 persons, whole blood data) Romanas Chaleckis (Nagoya City University) Homo sapiens blood metabolome; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2016-03
MTBLS261 MetaboLights Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse (NMR assay) Jules Griffin (Imperial College London) Mus musculus HP:Hepatic steatosis; CHMO:nuclear magnetic resonance spectroscopy; targeted metabolites; BMT:Functional genomics; EFO:obesity 2018-10
MTBLS266 MetaboLights Individual variability in human blood metabolites identifies age-related differences (30 persons, plasma data) Romanas Chaleckis (Nagoya City University) Homo sapiens blood metabolome; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2016-03
MTBLS264 MetaboLights Individual variability in human blood metabolites identifies age-related differences - constant blood metabolite levels during 24h in 4 individuals Romanas Chaleckis (Nagoya City University) Homo sapiens blood metabolome; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; NCIT:Variation; untargeted metabolites 2016-03
MTBLS267 MetaboLights Individual variability in human blood metabolites identifies age-related differences (30 persons, RBC data) Romanas Chaleckis (Nagoya City University) Homo sapiens blood metabolome; CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2016-03
MTBLS270 MetaboLights A new method for quantitative determination of bitter components of Belgian endive, with a focus on sesquiterpene oxalates Carlo Annaratone (Katholieke Universiteit Leuven) Cichorium intybus SWEET:Horticulture; CHEBI:sesquiterpene; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2016-01
MTBLS274 MetaboLights Traditional Aboriginal Preparation Alters the Chemical Profile of Carica papaya Leaves and Impacts on Cytotoxicity towards Human Squamous Cell Carcinoma Thao Nguyen (The University of Queensland) Carica papaya untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Botanical Therapy; EFO:cancer; SNOMEDCT:Australian aborigine 2017-05
MTBLS273 MetaboLights Metabolic phenotyping of ex-vivo breast samples by DESI mass spectrometry imaging JamesS McKenzie (Imperial College, London) Homo sapiens CHMO:desorption electrospray ionisation mass spectrometry; untargeted metabolites; DOID:breast cancer 2016-04
MTBLS275 MetaboLights Hepatotoxicity and nephrotoxicity induced by the chlorpyrifos and chlorpyrifos-methyl metabolite, 3,5,6-trichloro-2-pyridinol, in orally exposed mice Yan Zhang (Nanjing University) Mus musculus untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; CHEBI:3,5,6-trichloropyridine-2-one; CHEBI:organophosphorus insecticide; Subchronic effects 2017-05
MTBLS272 MetaboLights The Lipopolysaccharide-Induced Metabolome Signature in Arabidopsis thaliana Reveals Dynamic Reprogramming of Phytoalexin and Phytoanticipin Pathways Fidele Tugizimana (University of Johannesburg) Arabidopsis thaliana untargeted metabolites; EFO:metabolomic profiling; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:camalexin; CHEBI:glucosinolate; CHEBI:lipopolysaccharide; PLOSTHES:Multivariate data analysis; CHMO:tandem mass spectrometry 2017-05
MTBLS276 MetaboLights Diversity in DNA: Identification of methylated deoxyadenosines in higher eukaryotes AnaSofia HenriquesdaCosta (Cold Spring Harbor Laboratory) Escherichia coli::blank::Xenopus laevis::reference compound CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:DNA Analysis; CHMO:tandem mass spectrometry; targeted metabolites 2015-11
MTBLS278 MetaboLights Metabolomics dataset of PPAR-pan treated rat liver (eicosanoid assay) Zsuzsanna Ament (MRC HNR) Rattus norvegicus PPARs; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; CSEO:Lipidomics; CHEBI:icosanoid 2016-05
MTBLS279 MetaboLights Metabolic characterization of the natural progression of chronic hepatitis B (Lipid assays) Michael vanVliet (Leiden University) Homo sapiens targeted metabolites; CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:chronic hepatitis B infection 2016-06
MTBLS277 MetaboLights Multi-omics toxicity profiling of engineered nanomaterials Marc Rurik (University of Tuebingen) Homo sapiens ENM:nanomaterial; toxicity profiling; BTO:A-549 cell; BTO:THP-1 cell; BTO:lung; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2016-12
MTBLS281 MetaboLights Sponge exhalent seawater contains a unique chemical profile of dissolved organic matter Cara Fiore (Woods Hole Oceanographic Institution) sea water::Ircinia campana::Spheciospongia vesparium::Coral reef sea water::Pooled quality control ENVO:marine sponge reef; dissolved organic matter; ENVO:coral reef; CHMO:liquid chromatography-mass spectrometry; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; untargeted metabolites; targeted metabolites 2016-02
MTBLS282 MetaboLights 3D DESI mass spectrometry imaging of 51 serial sections from a human liver metastasis JamesS McKenzie (Imperial College, London) Homo sapiens/Mus musculus xenograft DOID:liver cancer; CHMO:desorption electrospray ionisation mass spectrometry; untargeted metabolites 2016-04
MTBLS283 MetaboLights Metabolomics profiling (GC-MS and LC-MS) for time-course differentiation of pre-B cells-like (B3 cell line) under the controlled induction of the transcription factor Ikaros (STATegra Project) RAFAEL HERNANDEZ (Príncipe Felipe Research Center (CIPF)) Mus musculus untargeted metabolites; STATegra; NCIT:DNA-Binding Protein Ikaros; time-course differentiation; pre-B cell line B3; CHMO:gas chromatography-mass spectrometry; CHMO:tandem mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry 2016-12
MTBLS286 MetaboLights Identification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (LC-MS pos assay) Chaoyang Hu (School of Life Sciences and Biotechnology, Shanghai Jiao Tong University) blank::Oryza sativa untargeted metabolites; GO:seed development; CHMO:ultra-performance liquid chromatography-mass spectrometry 2016-05
MTBLS287 MetaboLights Identification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (LC-MS neg assay) Chaoyang Hu (School of Life Sciences and Biotechnology, Shanghai Jiao Tong University) Oryza sativa::blank untargeted metabolites; GO:seed development; CHMO:ultra-performance liquid chromatography-mass spectrometry 2016-05
MTBLS288 MetaboLights Identification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (GC-MS assay) Chaoyang Hu (School of Life Sciences and Biotechnology, Shanghai Jiao Tong University) blank::Oryza sativa untargeted metabolites; GO:seed development; CHMO:gas chromatography-mass spectrometry 2016-05
MTBLS280 MetaboLights Metabolic characterization of the natural progression of chronic hepatitis B (Biogenic amine and Acyl-carnitine assays) Michael vanVliet (Leiden University) Homo sapiens targeted metabolites; CHEBI:amine; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:chronic hepatitis B infection; CHEBI:O-acylcarnitine 2016-06
MTBLS289 MetaboLights Analysis of colorectal adenocarcinoma tissue samples by DESI mass spectrometry imaging JamesS McKenzie (Imperial College, London) Homo sapiens/Mus musculus xenograft DOID:colorectal adenocarcinoma; untargeted metabolites; CHMO:desorption electrospray ionisation mass spectrometry 2016-04
MTBLS284 MetaboLights Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism Anna Kottgen (Medical Center - University of Freiburg) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Population Study; NCIT:Genetics; IOBC:metabolon; CHMO:tandem mass spectrometry 2021-03
MTBLS290 MetaboLights Normalization techniques for PARAFAC modeling of urine metabolomics data Radana Karlikova (IMTM, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 5, 775 15 Olomouc, Czech Republic) Homo sapiens::blank Parallel factor analysis; Compositional data; targeted metabolites; CHEBI:creatinine; NCIT:Area Under Curve; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2017-05
MTBLS291 MetaboLights LipidFrag: Improving reliability of in silico fragmentation of lipids and application to the Caenorhabditis elegans lipidome Christoph Ruttkies (IPB Halle) Caenorhabditis elegans::reference compound::Sus scrofa::Gallus gallus CHMO:ultra-performance liquid chromatography-mass spectrometry; CSEO:Lipidomics; Lipid identification benchmark; NCIT:Benchmark; untargeted metabolites 2017-03
MTBLS293 MetaboLights Metabolites from surface seawater collected in Narragansett Bay Krista Longnecker (Woods Hole Oceanographic Institution) sea water MESH:Carbon; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; CHMO:liquid chromatography-mass spectrometry; untargeted metabolites; targeted metabolites 2016-01
MTBLS292 MetaboLights Clock regulation of metabolites reveals coupling between transcription and metabolism Saikumari Krishnaiah (University of Pennsylvania) Homo sapiens::Mus musculus EFO:circadian rhythm; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:replicate; EFO:metabolomic profiling; targeted metabolites 2017-04
MTBLS297 MetaboLights Multiomics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites Steffen Neumann (Leibniz Institute of Plant Biochemistry) Solanum habrochaites::Solanum lycopersicum Plant Metabolomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; targeted metabolites; MTBLS:BioSamples 2017-04
MTBLS295 MetaboLights A Phosphate starvation response gene (psr1-like) is present in Micromonas pusilla and other marine algae and coordinates the metabolic response to phosphate deficiency Cara Fiore (Woods Hole Oceanographic Institution) Micromonas pusilla ADW:Phytoplankton; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; CHMO:liquid chromatography-mass spectrometry; untargeted metabolites; targeted metabolites 2016-02
MTBLS296 MetaboLights Deep functional analysis of synII, a 770 kb synthetic yeast chromosome Yanqun Fan (BGI) Saccharomyces cerevisiae ENVO:yeast product; GMO:Yeast extract; NCIT:Quality Control; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; MTBLS:Lipidomics 2016-10
MTBLS298 MetaboLights Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease Matej Oresic (University of Turku) Homo sapiens EFO:non-alcoholic fatty liver disease; NCIT:Catheterization; CHMO:two-dimensional chromatography; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2016-12
MTBLS304 MetaboLights Comparative label-free lipidomic analysis of Mycobacterium tuberculosis during dormancy and reactivation Sajith Raghunandanan (Rajiv Gandhi Centre For Biotechnology) Mycobacterium tuberculosis EFO:Tuberculosis; GO:dormancy process; GALEN:Hypoxia; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2018-10
MTBLS303 MetaboLights Metabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays) Zsuzsanna Ament (MRC HNR) Rattus norvegicus targeted metabolites; CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; PPARs; CHEBI:O-acylcarnitine 2016-05
MTBLS301 MetaboLights Dissection of two routes to naïve pluripotency using different kinase inhibitors Javier Munoz (Spanish National Cancer Research Center (CNIO)) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IMR:MEK1/2(MKK1/2); Gsk3b; CDK8; CDK19; IOBC:metabolon; CHMO:tandem mass spectrometry 2021-02
MTBLS306 MetaboLights Metabolomic Profiling of Submaximal Exercise at a Standardised Relative Intensity in Healthy Adults AliMuhsen Ali (University of strathclyde) Homo sapiens::reference compound untargeted metabolites; EFO:exercise; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; CMO:maximal oxygen consumption; CHEBI:purines; CHEBI:O-acylcarnitine 2017-05
MTBLS307 MetaboLights Molecular networking coupled to high-resolution mass spectrometry fragmentation reveals a multitude of urinary antihypertensive drug metabolites Justin vanderHooft (Bioinformatics Group - Wageningen University) Homo sapiens::blank::reference compound EFO:drug; CHMO:liquid chromatography-mass spectrometry; EFO:metabolic process; spectral similarity; EFO:biomolecular annotation design; untargeted metabolites; EFO:hypertension; MTBLS:Glasgow Polyomics 2016-05
MTBLS309 MetaboLights Metabolomic Responses of Guard Cells and Mesophyll Cells to Bicarbonate Biswapriya Misra (Texas Biomedical Research Institute) Brassica napus targeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; CHMO:gas chromatography-mass spectrometry; CHEBI:hydrogencarbonate; EFO:guard cell; EFO:mesophyll cell 2017-03
MTBLS313 MetaboLights FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry imaging MS (MALDI imaging assay) Andrew Palmer (EMBL) Mus musculus::Rattus rattus Spatial metabolomics; Metabolite-Signal Match (MSM) score; NCIT:False Discovery Rate; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; untargeted metabolites 2017-04
MTBLS310 MetaboLights A red wine intervention does not modify plasma trimethylamine N-oxide but is associated with broad shifts in the plasma metabolome and gut microbiota composition Elisa Haas (University of Sao Paulo - Heart Institure - InCor) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; EFO:coronary artery disease; FOODON:red wine 2024-05
MTBLS311 MetaboLights Metabolomic Responses of Arabidopsis Suspension Cells to Bicarbonate under Light and Dark Conditions Biswapriya Misra (Texas Biomedical Research Institute) Arabidopsis thaliana targeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; CHMO:gas chromatography-mass spectrometry; CHEBI:hydrogencarbonate 2017-04
MTBLS317 MetaboLights FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry - simulated Imaging MS (Imaging simulation assay) Andrew Palmer (EMBL) Simulation experiment Simulation experiment; Spatial metabolomics; Metabolite-Signal Match (MSM) score; NCIT:False Discovery Rate; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; targeted metabolites 2016-12
MTBLS300 MetaboLights Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives. Richard Robinson (Metabolon INC.) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolomics; CHMO:tandem mass spectrometry; IOBC:metabolon 2023-11
MTBLS316 MetaboLights Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast Takayuki Teruya (OIST) Schizosaccharomyces pombe untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; CHEBI:CDP-choline; CHEBI:ergothioneine; EFO:longevity; CHEBI:trehalose 2017-07
MTBLS315 MetaboLights Towards improving point-of-care diagnosis of non-malaria febrile illness: a metabolomics approach Saskia Decuypere (Telethon Kids Institute, Univeristy of Western Australia) Homo sapiens EFO:fever; EFO:sepsis; EFO:biomarker; NCIT:Diagnosis; EFO:malaria; CHMO:gas chromatography-mass spectrometry; CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; non-malarial febrile illness; untargeted metabolites 2016-03
MTBLS312 MetaboLights Jasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics Biswapriya Misra (Texas Biomedical Research Institute) Brassica napus targeted metabolites; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; CHMO:gas chromatography-mass spectrometry; EFO:guard cell; CHEBI:carbon dioxide; CHEBI:reactive oxygen species; jasmonate signalling; GO:stomatal movement 2017-04
MTBLS319 MetaboLights Metabolic analysis of the response of Pseudomonas putida DOT-T1E strains to toluene using Fourier transform infrared spectroscopy and gas chromatography mass spectrometry Drupad Trivedi (University of Manchester) Pseudomonas putida NCBITAXON:Bacteria; CHEBI:toluene; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2016-08
MTBLS321 MetaboLights eRah: A computational tool integrating spectral deconvolution and alignment with quantification and identification of metabolites in GCMS- based metabolomics Sara Samino (URV-CIBERDEM) Homo sapiens CHMO:gas chromatography-mass spectrometry; untargeted metabolites; eRah 2016-09
MTBLS320 MetaboLights Metabolomics analysis reveals the participation of efflux pumps and ornithine in the response of Pseudomonas putida DOT-T1E cells to challenge with propranolol Ali Sayqal (university of manchester) Pseudomonas putida NCBITAXON:Bacteria; CHEBI:propranolol; CHEBI:ornithine; GO:efflux pump complex; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2016-08
MTBLS322 MetaboLights Genomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep Martin Flck (University of Zurich) Ovis aries untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:rotator cuff tear; CSEO:Lipidomics; EFO:fat cell; NCIT:Gene Expression; MESH:Tenotomy; CPT:Anabolic steroids; NCIT:Androgen Receptor 2017-07
MTBLS326 MetaboLights 1H NMR Metabolomics Reveals Association of High Expression of Inositol 1, 4, 5 Trisphosphate Receptor and Metabolites in Breast Cancer Patients aru singh (Sanjay Gandhi Postgraduate Institute of Medical Sciences) Homo sapiens untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; Inositol 1,4,5 trisphosphate receptor; DOID:breast cancer 2017-07
MTBLS327 MetaboLights Mechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes (Mouse data) Jules Griffin (Imperial College London) Mus musculus MESH:Lipogenesis; EFO:diabetes mellitus; Direct Infusion Mass Spectrometry; MEDDRA:Dyslipidaemia; targeted metabolites 2017-03
MTBLS318 MetaboLights Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model Jason Rosch (SJCRH) Streptococcus pneumoniae CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; EFO:drug resistance; MCO:zinc stress; CHMO:tandem mass spectrometry 2022-02
MTBLS328 MetaboLights A microfluidics-based in vitro model of the gastrointestinal human-microbe interface Christian Jaeger (LUXEMBOURG CENTRE FOR SYSTEMS BIOMEDICINE) Homo sapiens::Lactobacillus rhamnosus EFO:metabolomic profiling; NCIT:Co-Culture; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2017-07
MTBLS331 MetaboLights Detection of adulteration in Iranian saffron samples by 1H NMR spectroscopy and multivariate data analysis techniques Farshad Farshidfar (University of Calgary) Crocus sativus MESH:Food Contamination; CHMO:nuclear magnetic resonance spectroscopy; targeted metabolites; NCIT:Saffron; NCIT:Intentionally Adulterated Product 2017-07
MTBLS330 MetaboLights The WEIZMASS spectral library for high-confidence metabolite identification NIR SHAHAF (The Aharoni Lab, Plant Sciences Dept., Weizmann Institute of Science) Spirodela polyrhiza::Arabidopsis thaliana::Wolffia::Lemna gibba::Solanum lycopersicum::Landoltia punctata untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; WEIZMASS; MatchWeiz 2018-03
MTBLS332 MetaboLights Two Poplar-Associated Bacterial Isolates Induce Additive Favorable Responses in a Constructed Plant-Microbiome System Collin Timm (Oak Ridge National Laboratory) Populus deltoides plant-microbe interactions; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; EFO:microbiome; NCIT:Burkholderia; NCIT:Pseudomonas 2017-07
MTBLS333 MetaboLights Discovery of A-type procyanidin dimers in yellow raspberries by untargeted metabolomics and correlation based data analysis Elisabete Carvalho (FEM) Rubus idaeus CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; MESH:procyanidin 2016-08
MTBLS334 MetaboLights Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics Elaine Cowan (Queens University Belfast) Mus musculus NCIT:Nutrition; CHEBI:Obestatin; EFO:obesity; EFO:diabetes mellitus; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2017-07
MTBLS337 MetaboLights The Poly (ADP-Ribose) Polymerase inhibitor Veliparib and Radiation Cause Significant Cell Line Dependent Metabolic Changes in Breast Cancer Cells Vijesh Bhute (University of Cambridge) Homo sapiens NCIT:Poly (ADP-Ribose) Polymerase Inhibitor; EFO:breast carcinoma; CHMO:nuclear magnetic resonance spectroscopy; EFO:cancer; NCIT:Radiation Therapy; EFO:cell line; untargeted metabolites 2016-11
MTBLS340 MetaboLights NMR-based metabonomics and correlative analysis reveals potential bomarkers associated with chronic atrophic gastritis Jiajia Cui (Modern Research Centre for Traditional Chinese Medicine of Shanxi University) Rattus norvegicus EFO:atrophic gastritis; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Correlative Study; EFO:biomarker; untargeted metabolites 2016-08
MTBLS335 MetaboLights Illuminating a plant’s tissue-specific metabolic diversity using computational metabolomics and information theory Dapeng Li (Max planck institute for chemical ecology) Nicotiana attenuata MESH:Secondary Metabolism; CHMO:tandem mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2016-12
MTBLS336 MetaboLights Biodiversity in marine invertebrate responses to acute warming revealed by a comparative multi-omics approach Ulf Sommer (University of Birmingham) Laternula elliptica::Yoldia eightsi::Marseniopsis mollis::Liothyrella uva::blank::Cucumaria georgiana::Paraceradocus miersii CHMO:nuclear magnetic resonance spectroscopy; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:heat tolerance; MESH:Global Warming; untargeted metabolites 2016-06
MTBLS342 MetaboLights Correspondence of coral holobiont metabolome with symbiotic bacteria, archaea and Symbiodinium communities Emilia Sogin (Hawaii Institute of Marine Biology ) Porites::Pocillopora meandrina::Acropora::Pocillopora acuta::Montipora::Montipora aequituberculata::Porites lobata::Porites rus BIOMODELS:Species; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites 2017-08
MTBLS343 MetaboLights Untargeted metabolomics approach using UPLC-ESI-QTOF-MS to explore the metabolome of fresh-cut iceberg lettuce Francisco TomasBarberan (CSIC) Lactuca sativa NCIT:Lettuce; NCIT:Storage; EDAM:Lipids; CHEBI:monoacylglycerol phosphate; CHEBI:phenols; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:sesquiterpene lactone; untargeted metabolites 2017-08
MTBLS341 MetaboLights Piriformospora indica stimulates root metabolism of Arabidopsis thaliana Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana EFO:genotype; EFO:hydroponic plant culture media; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2016-07
MTBLS338 MetaboLights Plant-to-plant variability in root metabolite profiles of 19 Arabidopsis thaliana accessions is substance-class dependent Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana EFO:genotype; EFO:hydroponic plant culture media; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2022-11
MTBLS349 MetaboLights Post-mortem changes in the metabolomic compositions of rabbit blood, aqueous and vitreous humors Vadim Yanshole (ITC SB RAS) Oryctolagus cuniculus untargeted metabolites; post-mortem interval; CHMO:nuclear magnetic resonance spectroscopy 2017-08
MTBLS346 MetaboLights Metabolic changes of genetically engineered grapes (Vitis vinifera L.) studied by 1H-NMR, metabolite heatmaps and iPLS Alessia Trimigno (University of Bologna) Vitis vinifera NCIT:Genetic Engineering; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; iPLS 2017-08
MTBLS345 MetaboLights Influence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome Tom Metz (Pacific Northwest National Laboratory) Animal feed::Mus musculus MESH:Systems Biology; EFO:microbiome; Collaborative Cross; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2016-10
MTBLS350 MetaboLights An Integrated Biochemical, Proteomics, and Metabolomics Approach for Supporting Medicinal Value of Panax ginseng Fruits (GC-MS assay) SunTae Kim (Pusan national university) Panax ginseng CHMO:gas chromatography-mass spectrometry; untargeted metabolites; EFO:antioxidant 2016-11
MTBLS353 MetaboLights Metabolite profile data of grapevine plants with brown wood streaking and grapevine leaf stripe (esca complex disease) symptoms Piebiep Goufo (Universidade de Trás-os-Montes e Alto Douro) Vitis vinifera CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; IOBC:metabolon; MTBLS:grapevine leaf stripe disease; MTBLS:grapevine trunk disease; MTBLS:esca complex disease; MTBLS:black-foot disease; MTBLS:Petri disease; MTBLS:phomopsis dieback; MTBLS:eutypa dieback; MTBLS:botryosphaeria dieback; MTBLS:white rot; MTBLS:brown wood streaking; NCIT:Lipidomics 2021-11
MTBLS356 MetaboLights A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome Angelica Palisi (University of Salerno - Pharmacy Department) Homo sapiens EFO:antiphospholipid syndrome; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites; MESH:Autoimmunity 2017-09
MTBLS354 MetaboLights Lipid metabolites as potential diagnostic and prognostic biomarkers for acute community acquired pneumonia Yan Bingpeng (The university of Hong Kong) Homo sapiens CHEBI:biomarker; CHEBI:glycolipid; CHEBI:phospholipid; EFO:pneumonia; CHEBI:sphingolipid; CHMO:ultra high performance liquid chromatography; untargeted metabolites 2016-08
MTBLS352 MetaboLights Lipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic and type 2 diabetic individuals Yanqun Fan (BGI) Homo sapiens CHMO:ultra high performance liquid chromatography; EFO:diabetes mellitus; EFO:lipid; MTBLS:untargeted metabolites 2017-04
MTBLS355 MetaboLights Nontargeted and targeted metabolomics measurements of abiotic stress responses in three-week-old Arabidopsis thaliana plants' rosette leaf tissue Elisabeth Georgii (Helmholtz Zentrum München) Arabidopsis thaliana EFO:genotype design; EFO:stimulus or stress design; CHMO:gas chromatography-mass spectrometry; MTBLS:targeted metabolites; MTBLS:untargeted metabolites 2017-07
MTBLS360 MetaboLights Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide Darren Creek (Monash University) blank::Trypanosoma brucei untargeted metabolites; EFO:human african trypanosomiasis; CSEO:Lipidomics; HINO:Sphingolipid metabolism; CHMO:ultra-performance liquid chromatography-mass spectrometry 2017-10
MTBLS359 MetaboLights Metabolomic analysis of the mechanism of action of yerba mate extract on Salmonella Typhimurium Caroline Rempe (University of Tennessee) Salmonella enterica BAO:antibacterial agent; SNOMEDCT:Plant extract; EFO:metabolomic profiling; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2017-02
MTBLS362 MetaboLights Molecular characterization of firefly nuptial gifts: a multi-omics approach sheds light on postcopulatory sexual selection TimothyR Fallon (UCSD/SIO) blank::Photinus pyralis targeted metabolites; CHMO:liquid chromatography-mass spectrometry; MESH:Fireflies 2016-12
MTBLS361 MetaboLights Kidney Tissue Targeted Metabolic Profiling of Unilateral Ureteral Obstruction Rats by NMR Zhenyu Li (Modern Research Center for Traditional Chinese Medicine of Shanxi University) Rattus norvegicus MP:renal interstitial fibrosis; EFO:metabolomic profiling; CHMO:nuclear magnetic resonance spectroscopy; targeted metabolites; unilateral ureteral obstruction 2017-10
MTBLS358 MetaboLights Chronic Obstructive Pulmonary Disease (COPD) Biomarker Identification Study: Serum Lipidomics Sam Ansari (PMI R&D) Homo sapiens CSEO:Lipidomics; NCIT:Tobacco Smoke; NCIT:Cigarette Smoking; NCIT:Prospective Cohort Study; NCIT:Chronic Obstructive Pulmonary Disease; MTBLS:Shotgun lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; targeted metabolites; Direct Infusion Mass Spectrometry; CHEBI:icosanoid 2017-02
MTBLS366 MetaboLights Using network analysis to discern compositional patterns in ultrahigh resolution mass spectrometry data of dissolved organic matter Krista Longnecker (Woods Hole Oceanographic Institution) sea water ENVO:sea water; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; Direct Infusion Mass Spectrometry; untargeted metabolites 2016-10
MTBLS363 MetaboLights Transcript, protein and metabolite temporal dynamics in the CAM plant Agave Nancy Engle (Oak Ridge National Laboratory) Agave americana::Arabidopsis thaliana untargeted metabolites; CHMO:gas chromatography-mass spectrometry; crassulacean acid metabolism 2017-10
MTBLS367 MetaboLights 13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys Alexander Hollis (University of Birmingham) Sus scrofa targeted metabolites; NCIT:Tracer; 13C-labelled glucose; Hypothermic machine perfusion; NCIT:Transplantation; CHMO:nuclear magnetic resonance spectroscopy; CHMO:two-dimensional nuclear magnetic resonance spectroscopy 2017-10
MTBLS372 MetaboLights Metabolomic profiling of Fraxinus excelsior genotypes tolerant or susceptible to ash dieback disease reveals changes in iridoid glycosides Christine Sambles (University of Exeter) Fraxinus excelsior NCBITAXON:Hymenoscyphus fraxineus; CHMO:liquid chromatography-mass spectrometry; MESH:Iridoid Glucosides; untargeted metabolites; Ash dieback; NCBITAXON:Agrilus planipennis; Danish Test Panel 2016-11
MTBLS364 MetaboLights Multiplatform serum metabolic phenotyping combined with pathway mapping to identify biochemical differences in smokers (UPLC-MS assay) Manuja Kaluarachchi (Metabometrix Ltd) Homo sapiens CHEBI:xenobiotic; CHEBI:biomarker; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2017-01
MTBLS370 MetaboLights A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms Stefan Weidt (University of Glasgow) Culture Media::Staphylococcus aureus; NCBITAXON:Candida albicans::Internal Standard::Staphylococcus aureus::Standard::Candida albicans::Bos taurus MESH:Metabolomics; BTO:biofilm; gas chromatography-mass spectrometry; targeted metabolites; untargeted metabolites; MTBLS:Glasgow Polyomics 2017-02
MTBLS374 MetaboLights Multiplatform serum metabolic phenotyping combined with pathway mapping to identify biochemical differences in smokers (NMR assay) Manuja Kaluarachchi (Metabometrix Ltd) Homo sapiens CHEBI:xenobiotic; CHEBI:biomarker; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2017-01
MTBLS375 MetaboLights Effects of MeJA on Arabidopsis metabolome under endogenous JA deficiency Jingjing Cao (China Agricultural University) Arabidopsis thaliana EFO:Arabidopsis thaliana; MMO:reverse transcription polymerase chain reaction; EFO:jasmonic acid; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2017-10
MTBLS378 MetaboLights FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry imaging MS (LC-MS assay) Andrew Palmer (EMBL) Mus musculus Spatial metabolomics; Metabolite-Signal Match score; NCIT:False Discovery Rate; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2016-12
MTBLS368 MetaboLights Nicotinamide Riboside is Uniquely Bioavailable in People and Mice Samuel Trammell (University of Iowa) blank::Mus musculus::Homo sapiens::reference compound CHMO:high-performance liquid chromatography-mass spectrometry; NDFRT:VITAMIN B3; CHEBI:nicotinic acid; MESH:nicotinamide-beta-riboside; CHEBI:nicotinic acid dinucleotide; targeted metabolites 2016-09
MTBLS379 MetaboLights Brain metabolomic profiling of eastern honey bee (Apis cerana) infested with the mite Varroa destructor mengnan huang (BGI) Apis cerana NATPRO:mite infestation; NCBITAXON:Varroa destructor; ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; CHMO:tandem mass spectrometry 2017-10
MTBLS376 MetaboLights Appropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach Hiroyuki Yamamoto (Human Metabolome Technologies) Mus musculus EFO:microbiome; CHMO:capillary electrophoresis-mass spectrometry; untargeted metabolites 2017-02
MTBLS381 MetaboLights Prediction, detection, and validation of isotope peaks in mass spectrometry data (Supplemental data for manuscript) Steffen Neumann (Leibniz Institute of Plant Biochemistry) reference compound CHMO:ultra-performance liquid chromatography-mass spectrometry; BAO:reference compound; untargeted metabolites 2016-10
MTBLS380 MetaboLights A metabolomic study of adipose tissue in mice with a disruption of the circadian system Cecilia Castro (University of Cambridge) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolomics; EFO:adipose tissue; EFO:circadian rhythm 2017-10
MTBLS382 MetaboLights A metabolomic study of adipose tissue in mice with a disruption of the circadian system Cecilia Castro (University of Cambridge) Mus musculus CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolomics; EFO:adipose tissue; EFO:circadian rhythm 2017-10
MTBLS383 MetaboLights Rapid Evaporative Ionisation Mass Spectrometry (REIMS) Provides Accurate Direct from Culture Species Identification within the Genus Candida Simon Cameron (Imperial College London) Candida inconspicua::Candida tropicalis::Pichia kudriavzevii::Meyerozyma guilliermondii::Candida albicans::Clavispora lusitaniae::Candida parapsilosis::Candida glabrata EFO:Fungi; CSEO:Lipidomics; CDAO:speciation; untargeted metabolites; Rapid Evaporative Ionisation Mass Spectrometry; CPT:Microbiology Procedures 2017-11
MTBLS386 MetaboLights Metabolomics of the human aqueous humor Vadim Yanshole (ITC SB RAS) Homo sapiens untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2017-11
MTBLS384 MetaboLights Serum-based metabolomics characterization of pigs treated with ractopamine tao peng (LaBoratoire d'Etude des Résidus et Contaminants dans les Aliments (LABERCA), Oniris, BP 50707, 44307 Nantes Cedex 3, France) Sus scrofa beta-agonist; growth promoter; MESH:Livestock; untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; EFO:biomarker; EDAM:Omics; CHEBI:ractopamine; ror:MetaboHUB 2017-06
MTBLS387 MetaboLights Snail reprograms glucose metabolism by repressing PFKP allowing cancer cell survival under metabolic stress Jueun Lee (Korea Basic Science Institute) Homo sapiens EFO:cancer; untargeted metabolites; CHMO:nuclear magnetic resonance spectrometer; CHMO:13C nuclear magnetic resonance spectroscopy; targeted metabolites; CHEBI:isotopic tracer; NCIT:Metastasis; NCIT:SNAI1 Gene 2017-11
MTBLS385 MetaboLights Desorption electrospray ionisation mass spectrometry imaging of esophageal lymph mode metastases JamesS McKenzie (Imperial College, London) Homo sapiens BTO:lymph node; EFO:neoplasm; NCIT:Metastasis; CHMO:desorption electrospray ionisation mass spectrometry; untargeted metabolites 2017-01
MTBLS373 MetaboLights Non-targeted in vitro metabolomics for proteome-scale identification of novel enzymes in Escherichia coli Nicola Zamboni (ETH Zurich) Escherichia coli EDAM:Functional genomics; non-targeted metabolites; enzyme discovery; MS:flow injection analysis 2016-01
MTBLS391 MetaboLights Lipid Data Analyzer: Discrimination of isobaric pairs of lipid standards from different lipid subclasses (Control experiment 2) Juergen Hartler (Institute of Pharmaceutical Sciences, University of Graz) reference compound untargeted metabolites; CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Software Engineering; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2017-10
MTBLS392 MetaboLights Core Microbiota and Metabolome of Vitis vinifera L. cv. Corvina Grapes and Musts Irene Stefanini (University of Warwick) Vitis vinifera NCIT:Wine; CHMO:fermentation; two-dimensional gas chromatography mass spectrometry; untargeted metabolites; RCD:Volatile compound; fungal population 2017-11
MTBLS390 MetaboLights A metabolomic study of adipose tissue in mice with a disruption of the circadian system Cecilia Castro (University of Cambridge) Mus musculus CHMO:gas chromatography-flame ionisation detection; targeted metabolomics; EFO:adipose tissue; EFO:circadian rhythm 2017-10
MTBLS389 MetaboLights Accumulation of the coumarin scopolin under abiotic stress conditions is mediated by the Arabidopsis thaliana THO/TREX complex Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana Plant metabolomics; secondary metabolites; EFO:genotype design; CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolites 2018-02
MTBLS393 MetaboLights Metabolomic analysis of riboswitch containing E. coli recombinant expression system Yun Xu (University of Manchester) Escherichia coli MESH:enhanced green fluorescent protein; untargeted metabolites; Inducer conditions; CHMO:gas chromatography-mass spectrometry; MESH:Riboswitch 2017-11
MTBLS399 MetaboLights Comparison of Chemical Compositions in Pseudostellariae Radix from Different Cultivated Fields and Germplasms by NMR-Based Metabolomics Yujiao Hua (Nanjing University of Chinese Medicine) Pseudostellaria heterophylla CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites; ENVO:cultivated environment; EFO:germplasm 2018-01
MTBLS397 MetaboLights Lipid Data Analyzer: The LDA algorithm against the in silico library LipidBlast (LipidBlast benchmarking experiment) Juergen Hartler (Institute of Pharmaceutical Sciences, University of Graz) Mus musculus::reference compound untargeted metabolites; CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Software Engineering 2017-11
MTBLS394 MetaboLights Lipid Data Analyzer: Decision rule set development by lipid standards of known constituent fatty acyl and/or alkyl/1-alkenyl chains and their respective sn-positions (Control experiment 1) Juergen Hartler (Institute of Pharmaceutical Sciences, University of Graz) reference compound untargeted metabolites; CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Software Engineering; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2017-10
MTBLS395 MetaboLights NMR-based metabolomics identifies patients at high risk of death within two years after acute myocardial infarction in the AMI-Florence II cohort Alessia Vignoli (CERM University of Florence) Homo sapiens NCIT:Acute Coronary Syndrome; Serum global phenotyping; CHMO:nuclear magnetic resonance spectroscopy; targeted metabolites 2018-10
MTBLS400 MetaboLights Metabolic profiling of ob/ob mouse fatty liver using HR-MAS 1H-NMR combined with gene expression analysis reveals alterations in betaine metabolism and the transsulfuration pathway Mikheil Gogiashvili (Leibniz Institut für Analytische Wissenschaften - ISAS - e.V.) Mus musculus untargeted metabolites; CHMO:magic angle spinning nuclear magnetic resonance spectroscopy; MESH:Fatty Liver; EFO:non-alcoholic fatty liver disease; NCIT:ob/ob Mouse; One-carbon metabolism; Lactate editing 2018-01
MTBLS396 MetaboLights Lipid Data Analyzer: Analysis of a complex biological system from murine liver samples (Murine liver lipidome experiment) Juergen Hartler (Institute of Pharmaceutical Sciences, University of Graz) Mus musculus untargeted metabolites; CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Software Engineering; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2017-11
MTBLS401 MetaboLights Mass spectrometry based metabolomics for in vitro systems pharmacology: Pitfalls, challenges, and computational solutions Stephanie Herman (Uppsala University) Homo sapiens untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; OBI:software pipeline; EFO:drug 2017-08
MTBLS403 MetaboLights Characterization of white tea metabolome: comparison against green and black tea by a nontargeted metabolomics approach Weidong Dai (Tea Research Institute, Chinese Academy of Agricultural Sciences) Camellia sinensis NDDF:white tea; withering; dynamic change; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2017-03
MTBLS398 MetaboLights Lipid Data Analyzer: Discrimination of structurally isomeric pairs of lipid standards (Control experiment 3) Juergen Hartler (Institute of Pharmaceutical Sciences, University of Graz) reference compound untargeted metabolites; CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Software Engineering; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2017-11
MTBLS404 MetaboLights Analysis of the human adult urinary metabolome variations with age, body mass index and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses. ('Sacurine' data set) EtienneA Thevenot (Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA)) Homo sapiens NCIT:Cohort Study; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; ror:MetaboHUB 2017-01
MTBLS409 MetaboLights RNA-Seq and UHPLC-Q-TOF/MS Based Lipidomics Study in Lysiphlebia japonica Xueke Gao (Chinese Academy of Agricultural Sciences) Aphis gossypii::Blank::Lysiphlebia japonica targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CSEO:Lipidomics; NCIT:Parasite 2021-10
MTBLS405 MetaboLights Proteomic and metabolic changes in cancer cells after alternation of SHMT2 expressions Jiefei Tong (Hospital for Sick Children) Homo sapiens targeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; DINTO:serine hydroxymethyltransferase 2 2020-08
MTBLS410 MetaboLights Lipidomics and RNA-Seq Study of Lipid Regulation in Aphis gossypii parasitized by Lysiphlebia japonica Xueke Gao (Chinese Academy of Agricultural Sciences) Blank::Aphis gossypii targeted metabolomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Parasite; MTBLS:Lipidomics 2018-03
MTBLS408 MetaboLights Lipidomics profiling reveals the role of glycerophospholipid metabolism in psoriasis Zeng Vera (BGI) Homo sapiens EDAM:Lipids; NCIT:Psoriasis; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolomics; MTBLS:Lipidomics 2017-08
MTBLS412 MetaboLights Stable isotope resolved analysis of HUVEC Cells under normaxia and hypoxia Philippe RoccaSerra (University of Oxford) Homo sapiens::reference compound isotopic abundance correction; targeted metabolites; CHMO:gas chromatography-mass spectrometry 2017-12
MTBLS411 MetaboLights Lactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids’ metabolomics relationships in dairy cows Huizeng Sun (Institute of Dairy Science, Zhejiang University) Bos taurus untargeted metabolites; CHMO:gas chromatography-mass spectrometry; Biofluids relationship; GO:lactation; Metabolic function 2018-03
MTBLS407 MetaboLights An online atlas of human plasma metabolite signatures of gut microbiome composition Tove Fall (Uppsala University, Department of Medical Sciences, Molecular Epidemiology) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; OHMI:human gut microbiome; CHEBI:biomarker 2022-05
MTBLS413 MetaboLights Metabolomics identifies multiple candidate biomarkers to diagnose and stage human African trypanosomiasis Stefan Weidt (University of Glasgow) blank::Homo sapiens::reference compound EFO:human african trypanosomiasis; NCBITAXON:Trypanosoma brucei; CHMO:liquid chromatography-mass spectrometry; EFO:infectious disease biomarker; untargeted metabolites; MTBLS:Glasgow Polyomics 2018-01
MTBLS406 MetaboLights Azithromycin promotes relapse by disrupting immune and metabolic networks after allogeneic stem cell transplantation David Michonneau (APHP) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; NCIT:Allogeneic Hematopoietic Stem Cell Transplantation; NCIT:Tumor Immunity; NCIT:Azithromycin; NCIT:Randomized Clinical Trial; CHMO:tandem mass spectrometry 2022-08
MTBLS414 MetaboLights Untargeted Metabolomics Reveals a Mild Impact of Remote Ischemic Conditioning on the Plasma Metabolome and α-Hydroxybutyrate as a Possible Cardioprotective Factor and Biomarker of Tissue Ischemia Mogens Johannsen (Aarhus University) Homo sapiens Remote ischemic conditioning; MESH:Ischemic Preconditioning; untargeted metabolites; CHEBI:2-hydroxybutyrate; cardioprotection; DOID:ischemia; NCIT:Biomarker; CHMO:ultra-performance liquid chromatography-mass spectrometry 2016-12
MTBLS415 MetaboLights 3D DESI mass spectrometry imaging of 52 serial sections from a human colorectal adenocarcinoma JamesS McKenzie (Imperial College, London) Homo sapiens CHMO:desorption electrospray ionisation mass spectrometry; untargeted metabolites 2017-03
MTBLS418 MetaboLights Serum Metabolic Profiling of Oocyst-Induced Toxoplasma gondii Acute and Chronic Infections in Mice Using Mass-Spectrometry mengnan huang (BGI) Mus musculus EFO:toxoplasmosis; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; CHMO:tandem mass spectrometry 2018-04
MTBLS417 MetaboLights Customized Consensus Spectral Library Building for Untargeted Quantitative Metabolomics Analysis with Data Independent Acquisition Mass Spectrometry and MetaboDIA Workflow Hyungwon Choi (National University of Singapore) Homo sapiens untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MetaboDIA; MS:combined ms-ms + spectral library search; EFO:age-related macular degeneration 2018-03
MTBLS420 MetaboLights Untargeted metabolomic profiling of seminal plasma in nonobstructive azoospermia men: A noninvasive detection of spermatogenesis Kambiz Gilany (Avicenna Research Institute) Homo sapiens untargeted metabolites; EFO:Male infertility with spermatogenesis disorder; chemometrics; CHMO:gas chromatography-mass spectrometry; nonobstructive azoospermia 2018-04
MTBLS419 MetaboLights Evidence of a DHA signature in the lipidome and metabolome of human hepatocytes veronica ghini (CERM) Homo sapiens CHEBI:docosahexaenoic acid; CHEBI:3,4-dihydroxybenzoic acid; CHEBI:propionic acid; NCIT:Metabolomics; CSEO:Lipidomics; CHMO:nuclear magnetic resonance spectrometer; targeted metabolites 2017-03
MTBLS422 MetaboLights Divergent relationships between faecal microbiota and metabolome following distinct antibiotic-induced disruptions Tokuwa Kanno (King's College London) Mus musculus EFO:antibiotic; CHMO:nuclear magnetic resonance spectrometer; untargeted metabolites 2017-03
MTBLS423 MetaboLights Untargeted metabolomics identifies a plasma sphingolipid-related signature associated with lifestyle intervention in prepubertal children with obesity Sara Samino (URV-CIBERDEM) Homo sapiens NCIT:Preventive Intervention; EFO:obesity; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2018-02
MTBLS425 MetaboLights Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes Vijesh Bhute (University of Cambridge) Homo sapiens EFO:stem cell; NCIT:Cardiomyocyte; NCIT:Cell Maturation; EFO:biomarker; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites; EFO:cardiovascular disease 2018-04
MTBLS426 MetaboLights Sexual dimorphism in the fetal cardiac response to maternal nutrient restriction Tom Metz (Pacific Northwest National Laboratory) Papio anubis CSEO:Lipidomics; maternal undernutrition; MP:cardiac fibrosis; EFO:sexual dimorphism; NCIT:Autophagy; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:MicroRNA 2018-04
MTBLS428 MetaboLights Dissolved organic carbon compounds in deep-sea hydrothermal vent fluids from the East Pacific Rise at 9°50′N Krista Longnecker (Woods Hole Oceanographic Institution) blank::sea water MESH:Carbon; targeted metabolites; CHMO:liquid chromatography-mass spectrometry 2017-05
MTBLS431 MetaboLights Transcriptomic and Metabolomics Profiling of Phage–Host Interactions between Phage PaP1 and Pseudomonas aeruginosa xia zhao (Third millitary medical school) Pseudomonas aeruginosa untargeted metabolites; NCIT:Bacteriophage; CHMO:nuclear magnetic resonance spectroscopy; phage–host interaction; EDAM:Transcriptomics 2018-05
MTBLS427 MetaboLights SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids Tom Metz (Pacific Northwest National Laboratory) Homo sapiens Ion Mobility Spectrometry; untargeted metabolites; Exposomics; EFO:diabetes mellitus; targeted metabolites; Solid-Phase Extraction Ion Mobility Spectrometry Mass Spectrometry 2017-02
MTBLS429 MetaboLights The correlation between leaf-surface and leaf-tissue secondary metabolites: a case study with pyrrolizidine alkaloids in Jacobaea hybrid plants Patrick Mulder (RIKILT Wageningen University & Research) Jacobaea CHEBI:pyrrolizidine alkaloid; insect-plant interactions; ultra-performance liquid chromatography-mass spectrometry; targeted metabolites 2018-05
MTBLS424 MetaboLights Serum metabolomic profiles identify ER-positive early breast cancer patients at increased risk of disease recurrence in a multicentre population veronica ghini (CERM) Homo sapiens Early breast cancer; MEDDRA:Metastatic breast cancer; NIFSTD:metabolic phenotyping; CHMO:nuclear magnetic resonance spectroscopy; targeted metabolites 2017-03
MTBLS430 MetaboLights Biological Effects of Amphiphilic Copolymer Nanoparticle-Encapsulated Multi-target Chemotherapeutic Drugs on MCF-7 Human Breast Cancer Cells Yili Hu (Wuhan Institute of Physics and Mathematics, CAS ) Homo sapiens CHMO:nuclear magnetic resonance spectroscopy; EFO:cancer; EFO:drug role; NCIT:Metabolic Response; untargeted metabolites 2018-05
MTBLS435 MetaboLights The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism Liu xiubin (Hunan Agricultural University) Macleaya cordata Plant Metabolomics; NCIT:Metabolic Pathway; CHMO:ultra-performance liquid chromatography-mass spectrometry; BAO:isotopic tracer; targeted metabolomics; CHEBI:benzylisoquinoline alkaloid; CHEBI:chelerythrine; CHEBI:sanguinarine; MESH:Secondary Metabolism 2017-04
MTBLS433 MetaboLights Olive Oil Authenticity Studies by Target and Non-target LC-QTOF-MS combined with Advanced Chemometric Techniques Steffen Neumann (Leibniz Institute of Plant Biochemistry) Olea europaea Foodomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; targeted metabolites 2017-05
MTBLS432 MetaboLights Stability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation Maria Glymenaki (University of Manchester ) Mus musculus EFO:inflammatory bowel disease; EFO:microbiome; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:gastrointestinal system; untargeted metabolites 2017-07
MTBLS437 MetaboLights Seed Metabolome Analysis of a Transgenic Rice Line Expressing Cholera Toxin B-subunit Takumi Ogawa (Osaka Prefecture University) Oryza sativa MESH:Plants, Genetically Modified; EFO:metabolomic profiling; CHMO:gas chromatography time-of-flight mass spectrometry; untargeted metabolites 2017-08
MTBLS436 MetaboLights Metabolomics analysis of liver reveals profile disruption in bovines upon steroid treatment Roberto Stella (Istituto Zooprofilattico Sperimentale delle Venezie) reference compound::Bos taurus untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MESH:Livestock; NCIT:Anabolic Steroid; EFO:biomarker 2018-05
MTBLS444 MetaboLights Quantitative metabolomic analysis of the human cornea and aqueous humor Vadim Yanshole (ITC SB RAS) Homo sapiens EFO:metabolomic profiling; untargeted metabolites; NCIT:Keratoconus; CHMO:nuclear magnetic resonance spectroscopy 2018-06
MTBLS440 MetaboLights Untargeted metabolomic analysis in cats with naturally occurring inflammatory bowel disease and alimentary small cell lymphoma Sina Marsilio (UC Davis School of Veterinary Medicine Dept. of Veterinary Medicine and Epidemiology) Felis catus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; CHEBI:biomarker; EFO:Cancer; MTBLS:feline chronic enteropathy; EFO:inflammatory bowel disease; MTBLS:small cell lymphoma 2021-07
MTBLS441 MetaboLights Stress-related mitogen-activated protein kinases stimulate the accumulation of small molecules and proteins in Arabidopsis thaliana root exudates Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; root exudate; plant defence 2017-08
MTBLS447 MetaboLights Metabolomic homeostasis shifts after callus formation and shoot regeneration in tomato Rameshwar Sharma (University of Hyderabad) Solanum lycopersicum EFO:metabolomic profiling; EFO:plant callus; GO:TOR signaling; CHMO:gas chromatography time-of-flight mass spectrometry; Shoot Regeneration; CHEBI:plant hormone; untargeted metabolites 2018-06
MTBLS442 MetaboLights Gut microbiota and fermentation-derived branched chain hydroxy acids mediate health benefits of yogurt consumption in obese mice Hana Koutnikova (Danone Nutricia Research) Mus musculus::Bos taurus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; EFO:insulin resistance; NCIT:Fermentation; ENVO:milk; ENVO:yogurt; IOBC:metabolon; CHMO:tandem mass spectrometry 2022-02
MTBLS449 MetaboLights Fetal Metabolic Stress Disrupts Immune Homeostasis and Induces Proinflammatory Responses in Human Immunodeficiency Virus Type 1- and Combination Antiretroviral Therapy-Exposed Infants Michael vanVliet (Leiden University) Homo sapiens MESH:HIV-1; NCIT:Antiretroviral Therapy; NCIT:In Utero Drug Exposure; MESH:Infant, Newborn; MESH:Fetal Blood; MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:icosanoid 2018-06
MTBLS445 MetaboLights Biogeography shaped the metabolome of the genus Espeletia: a phytochemical perspective on an Andean adaptive radiation Guillermo PadillaGonzalez (University of Sao Paulo) Espeletia untargeted metabolites; MESH:Phylogeography; CHMO:ultra-performance liquid chromatography-mass spectrometry; páramo ecosystem 2018-11
MTBLS451 MetaboLights Metabolite profiling of the fermentation process of yamahai-ginjo-shikomi Japanese sake Wataru Aoki (Kyoto University) Oryza sativa Japanese Sake; EFO:metabolomic profiling; CHMO:nanoflow liquid chromatography-electrospray ionisation mass spectrometry; untargeted metabolites 2018-06
MTBLS434 MetaboLights Functional Metabolomics Describes the Yeast Biosynthetic Regulome Michael Muelleder (The Francis Crick Institute) blank::reference compound::Saccharomyces cerevisiae targeted metabolites; EFO:amino acid; CHMO:hydrophilic interaction chromatography; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:haploid deletion library; EDAM:Functional genomics; PATO:prototrophic; EFO:metabolomic profiling; CHMO:tandem mass spectrometry 2017-03
MTBLS450 MetaboLights Functional metabolomics as a tool to analyze Mediator function and structure in plants Ilka Abreu (Dept. Plant Nutrition, Kiel University) Arabidopsis thaliana untargeted metabolites; NCIT:Mediator Complex; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-01
MTBLS454 MetaboLights Biosynthesis of Isonitrile Lipopeptides by Conserved Non-ribosomal Peptide Synthetase Gene Clusters in Actinobacteria Nick Harris (UC BERKELEY) Escherichia coli Isonitrile lipopeptides (INLPs); CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites; CHMO:tandem mass spectrometry 2017-07
MTBLS452 MetaboLights Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles Isabel Vincent (University of Glasgow) blank::Trypanosoma brucei CHEBI:benzoxaborole; MESH:Host-Pathogen Interactions; NCIT:Mechanism of Action; untargeted metabolites; pro-drug activation; NCIT:Drug Discovery; BRO:Therapeutics; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2018-02
MTBLS455 MetaboLights Using an NMR metabolomics approach to investigate the pathogenicity of amyloid-beta and alpha-synuclein MarieMargaret Phelan (University of Liverpool) Homo sapiens ADO:SHSY5Y; EFO:Parkinson's disease; EFO:Alzheimer's disease; CHMO:nuclear magnetic resonance spectroscopy; NIFSTD:Synuclein Protein; NIFSTD:Amyloid Protein; NIFSTD:Amyloid Fibril; NIFSTD:Amyloid Aggregate; untargeted metabolites 2018-06
MTBLS453 MetaboLights In Vitro 1H NMR Metabolic Profiles of Liver, Brain, and Serum in Rats After Chronic Consumption of Alcohol Mariya Krestina (ITC SB RAS) Rattus norvegicus NCIT:Toxicology; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Alcohol Consumption; untargeted metabolites 2023-02
MTBLS457 MetaboLights Survival, gene and metabolite responses of Litoria verreauxii alpina frogs to fungal disease chytridiomycosis Joel Gummer (Murdoch University) Litoria verreauxii Fungal biology; PLOSTHES:Conservation biology; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2018-01
MTBLS456 MetaboLights DIVA Metabolomics: Differentiating Vaccination Status Following Viral Challenge Using Metabolomic Profiles Darren Gray (Queen's University Belfast - Institute for Global Food Security) Bos taurus untargeted metabolites; viral infection-challenge; EFO:bovine respiratory disease complex; CHMO:ultra-performance liquid chromatography-mass spectrometry; VO:Bovine parainfluenza virus 3 2018-07
MTBLS460 MetaboLights Unraveling the metabolic response of Brassica oleracea exposed to Xanthomonas campestris pv. campestris Maria Tortosa (Mision Biologica de Galicia (MBG-CSIC)) Brassica oleracea PTO:biotic stress trait; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:Xanthomonas campestris pv. campestris; NIFSTD:Brassica oleracea var. italica; untargeted metabolites; CHMO:tandem mass spectrometry 2021-10
MTBLS459 MetaboLights Untargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei Isabel Vincent (University of Glasgow) Trypanosoma brucei NCIT:Drug Metabolism; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; CHMO:tandem mass spectrometry; CHEBI:nitrile; EFO:Oxidative Stress 2017-06
MTBLS461 MetaboLights Intracellular metabolites from an experimental manipulation of marine microorganisms Krista Longnecker (Woods Hole Oceanographic Institution) sea water targeted metabolites; MESH:Carbon; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; CHMO:liquid chromatography-mass spectrometry; untargeted metabolites 2017-05
MTBLS462 MetaboLights Lipid Data Analyzer: Novel lipid species and identification of regio-isomeric lipid species (HCD characterization and regioisomer detection) Juergen Hartler (Institute of Pharmaceutical Sciences, University of Graz) reference compound::Mus musculus untargeted metabolites; CSEO:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Software Engineering 2017-11
MTBLS465 MetaboLights A Metabonomic Comparison of Human Serum and Plasma Subtypes Using Untargeted NMR Spectroscopy and UPLC-MS (UPLC-MS assays) Manuja Kaluarachchi (Metabometrix Ltd) Homo sapiens ERO:metabolic phenotyping; CHEBI:biomarker; untargeted metabolomics; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-07
MTBLS464 MetaboLights Untargeted Metabolomics To Ascertain Antibiotic Modes of Action Isabel Vincent (University of Glasgow) Escherichia coli::blank::reference compound CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:antimicrobial agent; NCIT:Mechanism of Action; untargeted metabolites; CHMO:tandem mass spectrometry 2017-06
MTBLS470 MetaboLights A Metabonomic Comparison of Human Serum and Plasma Subtypes Using Untargeted NMR Spectroscopy and UPLC-MS (NMR assays) Manuja Kaluarachchi (Metabometrix Ltd) Homo sapiens CHEBI:biomarker; untargeted metabolomics; CHMO:nuclear magnetic resonance spectroscopy; ERO:metabolic phenotyping 2018-07
MTBLS467 MetaboLights Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells Jrgen Wess (NIH, NIDDK, Bethesda, MD, USA ) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHEBI:clenbuterol; EFO:diabetes mellitus; NCIT:Skeletal Muscle Tissue; CHMO:tandem mass spectrometry 2022-08
MTBLS471 MetaboLights Imaging with Mass Spectrometry of Bacteria on the Exoskeleton of Fungus-Growing Ants Kellen DeLaney (University of Wisconsin-Madison) Acromyrmex octospinosus CHMO:ultra-performance liquid chromatography-mass spectrometry; NCBITAXON:Pseudonocardia; untargeted metabolites; NCBITAXON:Escovopsis 2018-07
MTBLS472 MetaboLights ER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis Lynn Teesch (University of Iowa ) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; CSEO:Lipidomics; EFO:Endoplasmic Reticulum Stress; MESH:Fatty Liver; fatty kidney; MESH:Lipolysis; GO:fatty acid oxidation; NCIT:Unfolded Protein Response; MTBLS:untargeted metabolites 2017-06
MTBLS478 MetaboLights A multi-omics approach reveals functions of Secretory Carrier-Associated Membrane Proteins in wood formation of Populus trees Ilka Abreu (Dept. Plant Nutrition, Kiel University) Populus tremula x Populus tremuloides untargeted metabolites; PR:secretory carrier-associated membrane protein 1; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2018-01
MTBLS469 MetaboLights Two apples a day modulate human:microbiome co-metabolic processing of polyphenols, tyrosine and tryptophan Maria Ulaszewska (Fondazione Edmund Mach, Metabolomics Unit) Homo sapiens untargeted metabolites; EFO:Malus x domestica; NCIT:Cardiovascular Disorder; CHMO:high-performance liquid chromatography-mass spectrometry; CHEBI:Biomarker; CHEBI:Polyphenol 2020-04
MTBLS473 MetaboLights Host: Microbiome co-metabolic processing of dietary polyphenols – An acute, single blinded, cross-over study with different doses of apple polyphenols in healthy subjects Maria Ulaszewska (Fondazione Edmund Mach, Metabolomics Unit) Homo sapiens EFO:Malus x domestica; untargeted metabolites; BRO:Pharmacokinetics Pharmacodynamics; NCIT:Nutrition; CHMO:high-performance liquid chromatography-mass spectrometry 2018-10
MTBLS476 MetaboLights LC-HRMS Metabolomics for Untargeted Diagnostic Screening in Clinical Laboratories: A Feasibility Study bertrand rochat (CHUV UNIL) Homo sapiens untargeted metabolites; SIO:medical screening; NCIT:Diagnostic Procedure; NCIT:Toxicology; CHMO:ultra high performance liquid chromatography 2019-06
MTBLS479 MetaboLights A Combined LC-MS Metabolomics- and 16S rRNA Sequencing Platform to Assess Interactions between Herbal Medicinal Products and Human Gut Bacteria in Vitro: a Pilot Study on Willow Bark Extract EvaMaria PferschyWenzig (Institute of Pharmaceutical Sciences, Pharmacognosy, Universitaetsplatz 4/1, 8010 Graz, Austria) Homo sapiens::blank::PBS buffer CHMO:ultra-performance liquid chromatography-mass spectrometry; MESH:Gastrointestinal Microbiome; MESH:Herbal Medicine; untargeted metabolites; CHMO:tandem mass spectrometry; CHEBI:willow bark extract 2017-12
MTBLS481 MetaboLights Metabolomic analysis of alfalfa (Medicago sativa L.) root-symbiotic rhizobia responses under alkali stress Hua Cai (Northeast Agricultural University) Medicago sativa untargeted metabolites; alkali stress; symbiotic rhizobium; CHMO:gas chromatography time-of-flight mass spectrometry 2018-07
MTBLS483 MetaboLights LipidHunter Identifies Phospholipids by High-Throughput Processing of LC-MS and Shotgun Lipidomics Datasets (Rat cardiomyocyte assay) Zhixu Ni (University of Leipzig, Institute of Bioanalytical Chemistry, Fedorova Research Group) Rattus GO:regulation of cellular response to oxidative stress; BIOMODELS:lipid oxidation; EFO:Oxidative Stress; EFO:phospholipid; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; untargeted metabolites; MTBLS:Shotgun lipidomics 2018-07
MTBLS482 MetaboLights Effects of a Compound from the Group of Substituted Thiadiazines with Hypothermia Inducing Properties on Brain Metabolism in Rats, a Study In Vivo and In Vitro Oleg Shevelev (Institute of Cytology and Genetics The Siberian Branch of the Russian Academy of Sciences) Rattus norvegicus untargeted metabolites; NCIT:Magnetic Resonance Imaging; ERO:magnetic resonance spectroscopy; NCIT:Hypothermia; 2-morpholino-5-phenyl-6H-1,3,4-thiadiazine hydrobromide 2018-07
MTBLS484 MetaboLights Mass spectrometry data of metabolomics analysis of Nepenthes pitchers HOEHAN GOH (UNIVERSITI KEBANGSAAN MALAYSIA) Nepenthes ampullaria::blank::Nepenthes x hookeriana::Nepenthes rafflesiana untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; PLOSTHES:Carnivorous plants; MEO:pitcher plant 2018-07
MTBLS487 MetaboLights massPix: An R package for annotation and interpretation of mass spectrometry imaging data for lipidomics Zoe Hall (University of Cambridge) Mus musculus CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; Spatial metabolomics; CHEBI:lipid; EFO:software; NCIT:Lipidomics 2017-08
MTBLS494 MetaboLights Nontargeted Metabolomic Analysis of Four Different Parts of Platycodon grandiflorum Grown in Northeast China Jinping Liu (school of pharmaceutical sciences, Jilin University) Platycodon grandiflorus untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; MESH:Herbal Medicine; CHMO:tandem mass spectrometry 2017-08
MTBLS492 MetaboLights Linking soil biology and chemistry in biological soil crust using isolate exometabolomics Tami Swenson (Lawrence Berkeley National Lab) soil biocrust ENVO:soil; BOF:Environment; ENVO:environmental system; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-07
MTBLS495 MetaboLights Absolute quantitative lipidomics reveals lipidome-wide alterations in aging brain (Mouse brain NEG UPLC-MS assay) jia tu (Chinese Academy of Sciences) Mus musculus EFO:aging; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Lipidomics; EFO:lipid homeostasis 2018-08
MTBLS493 MetaboLights An LC–MS-based lipidomics pre-processing framework underpins rapid hypothesis generation towards CHO systems biotechnology HockChuan Yeo (Bioprocessing Technology Institute) Cricetulus griseus CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:lipid; Chinese Hamster Ovary cells; CSEO:Lipidomics; untargeted metabolites 2018-07
MTBLS488 MetaboLights Pharmacokinetic and urinary profiling reveals prednisolone/cortisol ratio as a valid biomarker for prednisolone administration Beata Pomian (UGhent) Bos taurus CHEBI:prednisolone; CHEBI:cortisol; MS:ms level; CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolites 2018-01
MTBLS496 MetaboLights Metabolomic profiling of Campylobacter jejuni with resistance gene ermB by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry and tandem quadrupole mass spectrometry qin fu (China Agricultural University) Campylobacter jejuni ermB; BAO:antibiotic resistance; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; CHMO:tandem mass spectrometry 2018-08
MTBLS516 MetaboLights Local and systemic metabolic alterations in brain, plasma, and liver of rats in response to aging and ischemic stroke, as detected by nuclear magnetic resonance (NMR) spectroscopy Vijesh Bhute (University of Cambridge) Rattus rattus EFO:Ischemic stroke; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; EFO:aging; EFO:biomarker 2019-02
MTBLS497 MetaboLights Headspace volatile organic compounds from bacteria implicated in ventilator-associated pneumonia analysed by TD-GC/MS Oluwasola Lawal (University of Manchester) Escherichia coli::Pseudomonas aeruginosa::Artificial sputum medium::Nutrient broth::blank::Klebsiella pneumoniae::Staphylococcus aureus untargeted metabolites; CHMO:thermal desorption-gas chromatography mass spectrometry; CHEBI:volatile organic compound; EFO:Bacteria; NCIT:Expired Air; NCIT:Infection; EFO:ventilator-associated pneumonia 2018-08
MTBLS519 MetaboLights The Kalanchoe genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism Nancy Engle (Oak Ridge National Laboratory) Kalanchoe fedtschenkoi untargeted metabolites; AURA:Crassulacean-Acid-Metabolism; PLOSTHES:Convergent evolution; CHMO:gas chromatography-mass spectrometry; NCIT:Photosynthesis 2018-01
MTBLS522 MetaboLights Effects of Centella asiatica extract on antioxidant status and liver metabolome of rotenone-treated rats using GC-MS Rossarin Tansawat (Chulalongkorn University) Rattus norvegicus CHMO:gas chromatography-mass spectrometry; untargeted metabolites; MESH:Centella asiatica extract; liver metabolome 2018-10
MTBLS517 MetaboLights MaHPIC Experiment 04: Metabolomics from Macaca mulatta infected with Plasmodium cynomolgi B strain to produce and integrate clinical, hematological, parasitological, and omics measures of acute primary infection and relapses Jessica Kissinger (Institute of Bioinformatics, University of Georgia) Homo sapiens::Macaca mulatta;NCBITAXON:Plasmodium cynomolgi NCIT:Malaria; Anti-malarial treatment; CHEBI:artemether; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2017-12
MTBLS523 MetaboLights Epithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic James MacRae (The Francis Crick Institute) Heligmosomoides polygyrus CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites; PLOSTHES:Helminth infections; PLOSTHES:Larvae; PR:Pla2g1b (mouse); CHMO:tandem mass spectrometry 2018-08
MTBLS518 MetaboLights MaHPIC Experiment 03: Metabolomics from Macaca mulatta infected with Plasmodium coatneyi Hackeri strain to produce and integrate clinical, hematological, parasitological, and omics measures of acute, recrudescent, and chronic infections Jessica Kissinger (Institute of Bioinformatics, University of Georgia) Homo sapiens::Macaca mulatta;NCBITAXON:Plasmodium coatneyi NCIT:Malaria; Anti-malarial treatment; CHEBI:artemether; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2017-09
MTBLS524 MetaboLights Identification of a discriminative metabolomic fingerprint of potential clinical relevance in saliva of patients with periodontitis using 1H nuclear magnetic resonance (NMR) spectroscopy MohamedNawfal Triba (Université Paris 13) Homo sapiens untargeted metabolites; EFO:periodontitis; EFO:biomarker; CHMO:nuclear magnetic resonance spectroscopy 2018-08
MTBLS520 MetaboLights Computational workflow to study the seasonal variation of secondary metabolites in nine different bryophytes Kristian Peters (IPB Halle) Calliergonella cuspidata::Polytrichum strictum::Rhytidiadelphus squarrosus::Hypnum cupressiforme::Plagiomnium undulatum::Brachythecium rutabulum::blank value::Grimmia pulvinata::Marchantia polymorpha::Fissidens taxifolius Ecological characteristics; Metabolite features; Secondary metabolites; ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2018-06
MTBLS526 MetaboLights Effects of coronatine elicitation on growth and metabolic profiles of Lemna paucicostata culture HyungKyoon Choi (Chung-Ang University) Lemna paucicostata untargeted metabolites; CHEBI:Coronatine; CHMO:gas chromatography-mass spectrometry 2018-09
MTBLS525 MetaboLights A synthetic community system for probing microbial interactions driven by exometabolites John Chodkowski (Michigan State University) Burkholderia thailandensis;NCBITAXON:Chromobacterium violaceum;NCBITAXON:Pseudomonas syringae untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2017-10
MTBLS527 MetaboLights The Green Tea Modulates Large Intestinal Microbiome and Exo/Endogenous Metabolome altered through Chronic UVB-exposure (Endogenous assays) EunSung Jung (Konkuk University) Mus musculus untargeted metabolites; DERMO:dermatoheliosis; NCIT:Ultraviolet B Radiation; NCIT:Green Tea; CHMO:gas chromatography time-of-flight mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-09
MTBLS528 MetaboLights The natural variance of the Arabidopsis floral secondary metabolites Takayuki Tohge (NAIST) Arabidopsis thaliana untargeted metabolites; MESH:Secondary Metabolism; BAO:plant; CHMO:high-performance liquid chromatography-mass spectrometry 2018-04
MTBLS531 MetaboLights A Multi-Omics Analysis of Glycine max Leaves Reveals Alteration in Flavonoid and Isoflavonoid Metabolism Upon Ethylene and Abscisic Acid Treatment SunTae Kim (Pusan national university) Glycine max CHEBI:ethylene group; CHEBI:(+)-abscisic acid; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; CHEBI:isoflavonoid; CHEBI:flavonoid; targeted metabolites 2018-09
MTBLS535 MetaboLights Comparative metabolomics of Mycoplasma bovis and Mycoplasma gallisepticum reveals fundamental differences in active metabolic pathways and suggests novel gene annotations Yumiko Masukagami (The University of Melbourne) Mycoplasma gallisepticum::Mycoplasma bovis EFO:Bacteria; untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:gas chromatography-mass spectrometry; targeted metabolites 2017-10
MTBLS530 MetaboLights Neuronal Hyperactivity due to Loss of Inhibitory Tone in APOE4 Mice Lacking Alzheimer’s Disease-like Pathology Tal Nuriel (Columbia University Medical Center) Mus musculus ADO:APOE; ADO:Late Onset Alzheimer's Disease; untargeted metabolites 2017-09
MTBLS532 MetaboLights Metabolomics reveals increased toxicity in earthworms (Eisenia fetida) of the transformation product methyl-triclosan Joseph Gillis (McGill University - Faculty of Agriculture and Environmental Science) Eisenia fetida MESH:Ecotoxicology; MTBLS:untargeted metabolites; CHMO:gas chromatography-mass spectrometry; CHEBI:triclosan; MESH:methyl triclosan 2018-09
MTBLS536 MetaboLights MaHPIC Experiment 30: Metabolomics from the pilot experiment for Macaca mulatta infected with Plasmodium knowlesi Malayan strain sporozoites to produce and integrate clinical, hematological, parasitological, omics, telemetric and histopathological measures of acute primary infection Jessica Kissinger (Institute of Bioinformatics, University of Georgia) Homo sapiens::Macaca mulatta;NCBITAXON:Plasmodium knowlesi NCIT:Malaria; Anti-malarial treatment; Artemether; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2017-10
MTBLS538 MetaboLights 13C metabolomics reveals widespread change in carbon fate during coral bleaching Katie Hillyer (Victoria University of Wellington ) Symbiodinium sp. ex Acropora aspera::Acropora aspera CHEBI:isotopic tracer; ENVO:coral bleaching process; PLOSTHES:Thermal stresses; MESH:Cnidaria; MESH:Symbiosis; CHMO:gas chromatography-mass spectrometry; GO:photoinhibition; untargeted metabolites 2018-12
MTBLS533 MetaboLights PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis Fabao Liu (UW-Madison) Homo sapiens::Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; EFO:cancer; NCIT:Energy Balance; CHMO:tandem mass spectrometry 2021-07
MTBLS529 MetaboLights A large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (HPLC-MS Hypercarb reverse phase NEG assay) Arvind Subbaraj (AgResearch Ltd.) blank::Lolium perenne CHEBI:fructan; CHMO:High-Performance Liquid Chromatography-Mass Spectrometry; untargeted metabolites 2019-03
MTBLS541 MetaboLights Effects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model MarieMargaret Phelan (University of Liverpool) Homo sapiens NCIT:Hypoxia; NIFSTD:cellular response to hypoxia; NCIT:Tumor Mass; EFO:cell culture; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2018-08
MTBLS543 MetaboLights Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies MarieMargaret Phelan (University of Liverpool) Equus caballus EFO:sepsis; EFO:Osteochondrosis; EFO:osteoarthritis; NCIT:Synovial Fluid; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2018-07
MTBLS540 MetaboLights J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis Andrea Rodriguez (Imperial College London) Homo sapiens untargeted metabolites; FGENTCARD; CHMO:nuclear magnetic resonance spectroscopy 2018-07
MTBLS545 MetaboLights Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay) Xiaojiao Zheng (Shanghai Sixth People's Hospital) Mus musculus EFO:high fat diet; EFO:gut microbiome measurement; EFO:obesity; CHMO:gas chromatography time-of-flight mass spectrometry; EFO:metabolomic profiling; untargeted metabolites 2017-11
MTBLS546 MetaboLights Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (targeted short chain fatty acid analysis assay) Xiaojiao Zheng (Shanghai Sixth People's Hospital) Mus musculus EFO:high fat diet; EFO:gut microbiome measurement; EFO:obesity; CHMO:gas chromatography time-of-flight mass spectrometry; targeted metabolites; CHEBI:short-chain fatty acid 2017-11
MTBLS548 MetaboLights Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (targeted free fatty acid analysis assay) Xiaojiao Zheng (Shanghai Sixth People's Hospital) Mus musculus EFO:high fat diet; EFO:gut microbiome measurement; EFO:obesity; CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolites; CHEBI:fatty acid 2017-11
MTBLS544 MetaboLights Plant species richness elicits changes in the metabolome of grassland species via soil biotic legacy Steffen Neumann (Leibniz Institute of Plant Biochemistry) Leucanthemum vulgare::Plantago lanceolata::Centaurea jacea::Knautia arvensis CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Ecology; The Jena Experiment; OMIT:Herbivory; MTBLS:chemical diversity; MTBLS:untargeted metabolites 2019-05
MTBLS547 MetaboLights Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (targeted bile acid analysis assay) Xiaojiao Zheng (Shanghai Sixth People's Hospital) Mus musculus EFO:high fat diet; EFO:gut microbiome measurement; EFO:obesity; CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolites; CHEBI:bile acid 2017-11
MTBLS542 MetaboLights MaHPIC Experiment 23: Metabolomics from Macaca mulatta infected with Plasmodium cynomolgi B strain to produce and integrate clinical, hematological, parasitological, and omics measures of acute primary infection and relapses Jessica Kissinger (Institute of Bioinformatics, University of Georgia) Homo sapiens::Macaca mulatta;NCBITAXON:Plasmodium cynomolgi NCIT:Malaria; Anti-malarial treatment; Artemether; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2017-12
MTBLS549 MetaboLights Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood Takayuki Teruya (OIST) Homo sapiens EFO:fasting; untargeted metabolites; human blood; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2019-09
MTBLS555 MetaboLights Exometabolomic profiling of bacterial strains cultivated using Arabidopsis root extract as the sole carbon source Richard Jacoby (University of Cologne) Arabidopsis thaliana rhizospheric; Exometabolomic profiling; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites 2018-10
MTBLS554 MetaboLights Discovery of urinary biomarkers to discriminate between exogenous and semi-endogenous thiouracil in cattle (Calf samples) Beata Pomian (UGhent) Bos taurus targeted metabolites; CHEBI:thiouracil; EFO:biomarker; MESH:Cattle; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-02
MTBLS552 MetaboLights Metabolomic alterations in invasive ductal carcinoma of breast: A comprehensive metabolomic study using tissue and serum samples TUSHAR MORE (National centre for cell science) Homo sapiens EFO:invasive ductal carcinoma; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; targeted metabolites 2018-10
MTBLS559 MetaboLights Similar, but different: structurally related azelaic acid and hexanoic acid trigger differential metabolomic and transcriptomic responses in tobacco cells Fidele Tugizimana (University of Johannesburg) Nicotiana tabacum plant priming; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; augmented defence; CHEBI:azelaic acid; CHEBI:hexanoic acid; CHEBI:hydroxycinnamic acid; NCIT:Transcriptomics; NCIT:Tobacco 2018-10
MTBLS553 MetaboLights Nonspecific activities of the major herbicide-resistance gene BAR Bastien Christ (Whitehead Institute for Biomedical Research) Triticum aestivum::Brassica napus::Glycine max::Brassica juncea::reference compound::Streptomyces viridochromogenes::Arabidopsis thaliana untargeted metabolites; targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; bialaphos resistance gene; phosphinothricin acetyltransferase gene; MESH:Herbicide Resistance; PLOSTHES:Genetically modified crops 2017-12
MTBLS558 MetaboLights Integration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis Stephanie Herman (Uppsala University) blank::Homo sapiens EFO:multiple sclerosis; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites; CHEBI:biomarker 2018-08
MTBLS562 MetaboLights Absolute quantitative lipidomics reveals lipidome-wide alterations in aging brain (Mouse brain POS UPLC-MS assay) jia tu (Chinese Academy of Sciences) Mus musculus EFO:aging; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Lipidomics; EFO:lipid homeostasis 2018-08
MTBLS560 MetaboLights Relationships between digestive efficiency and metabolomic profiles of serum and intestinal contents in chickens Stéphane Beauclercq (Université du Québec à Montréal) Gallus gallus EFO:digestive system; Digestive efficiency; EFO:ileum; EFO:caecum; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolomics 2018-05
MTBLS561 MetaboLights Discovery of urinary biomarkers to discriminate between exogenous and semi-endogenous thiouracil in cattle (Cow samples) Beata Pomian (UGhent) Bos taurus targeted metabolites; CHEBI:thiouracil; EFO:biomarker; MESH:Cattle; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-02
MTBLS564 MetaboLights 1H NMR Metabolomics Identifies Underlying Inflammatory Pathology in Osteoarthritis and Rheumatoid Arthritis Synovial Joints MarieMargaret Phelan (University of Liverpool) Homo sapiens untargeted metabolites; NCIT:Rheumatoid Arthritis; NCIT:Synovial Fluid; NCIT:Pathogenesis; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Osteoarthritis 2018-10
MTBLS566 MetaboLights Complete pathway elucidation and heterologous reconstitution of Rhodiola salidroside biosynthesis Tomas Pluskal (Whitehead Institute for Biomedical Research) Rhodiola rosea biosynthetic pathway elucidation; CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolites 2018-01
MTBLS563 MetaboLights NMR-based metabolic profiling provides diagnostic and prognostic information in critically ill children with suspected infection MarieMargaret Phelan (University of Liverpool) Homo sapiens OAE:bacterial sepsis AE; OAE:viral infection AE; OAE:sepsis AE; MESH:Intensive Care Units, Pediatric; DOID:viral infectious disease; IDO:systemic infection; IDO:local infection; IDO:focal infection; IDO:acute infection; hospital-acquired/nosocomial infection; IDO:community-acquired infection; NCIT:Clinical Diagnosis; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2020-11
MTBLS567 MetaboLights Intracellular and extracellular metabolites from three strains of Prochlorococcus Krista Longnecker (Woods Hole Oceanographic Institution) Prochlorococcus CHMO:liquid chromatography-mass spectrometry; targeted metabolites 2018-10
MTBLS571 MetaboLights Grazer-induced transcriptomic and metabolomic response of the chain-forming diatom Skeletonema marinoi Gran Nylund (Department of Marine Sciences, University of Gothenburg) Skeletonema marinoi Grazer cues; NCBITAXON:Calanus finmarchicus; CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites; ENVO:marine algal bloom 2018-10
MTBLS570 MetaboLights Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli Kevin Rattigan (University of Glasgow) blank::Mus musculus::reference compound EFO:inflammation; untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; ONL-DP:non-targeted object 2018-03
MTBLS572 MetaboLights Data processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online Tao Huan (The Scripps Research Institute) Escherichia coli untargeted metabolomics; MESH:Systems Biology; CHMO:high-performance liquid chromatography-mass spectrometry; SWO:xcms 2017-11
MTBLS577 MetaboLights The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast (Metabolome assay) Takayuki Teruya (OIST) Schizosaccharomyces pombe GEXO:Cwh43; BNO:Nutrition Roles; EFO:ceramide; Low glucose; Nitrogen starvation; untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2018-08
MTBLS578 MetaboLights The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast (Lipidome assay) Takayuki Teruya (OIST) Schizosaccharomyces pombe NCIT:Lipidomics; GEXO:Cwh43; BNO:Nutrition Roles; untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2018-08
MTBLS576 MetaboLights Creation and Characterization of a Genomically Hybrid Strain in the Nitrogen-Fixing Symbiotic Bacterium Sinorhizobium meliloti veronica ghini (CERM) Sinorhizobium meliloti CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites; replicon independence; genome coadaptation; experimental transplantation; accessory genome 2021-03
MTBLS575 MetaboLights Maize Stem Response to Long-Term Attack by Sesamia nonagrioides Victor Rodriguez (Mision Biologica de Galicia (MBG-CSIC)) Zea mays NCBITAXON:Sesamia nonagrioides; CHMO:ultra-performance liquid chromatography-mass spectrometry; NIGO:response to biotic stimulus; untargeted metabolites; plant defence 2018-05
MTBLS574 MetaboLights Chemocoding as an identification tool where morphological- and DNA-based methods fall short: Inga as a case study Thomas Kursar (University of Utah) Inga alata::Inga alba::Inga marginata::Inga coruscans::Inga umbellifera::Inga chartacea::Inga leiocalycina::Inga brachystachys::Inga pezizifera::Inga microcoma::Inga auristellae::Inga obidensis::Inga laurina::Inga acreana CRISP:chemical fingerprinting; untargeted metabolites; PLOSTHES:Chemical ecology; NCIT:Botany; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-01
MTBLS579 MetaboLights Diagnostic metabolite biomarkers of chronic typhoid carriage Elin Nsstrm (Department of Chemistry, Umeå University) Homo sapiens NCIT:Biomarker; EFO:typhoid fever; MEDDRA:Typhoid carrier; MESH:Salmonella typhi; MESH:Salmonella paratyphi A; untargeted metabolites; CHMO:two-dimensional chromatography-mass spectrometry; MESH:Multivariate Analysis; NCIT:Diagnosis 2018-01
MTBLS580 MetaboLights Explaining combinatorial effects of mycotoxins Deoxynivalenol and Zearalenone in mice with urinary metabolomic profiling Jian Ji (Jiangnan University) Mus musculus CHEBI:mycotoxin; MTBLS:gas chromatography-mass spectrometry; APAONTO:Mice; ACGT-MO:Toxicity; MTBLS:untargeted metabolites 2021-02
MTBLS581 MetaboLights Comparative metabolomic responses to gibberellic acid and 6-benzylaminopurine in Cunila menthoides Benth. (Lamiaceae): a contribution to understand the metabolic pathways JoanaPaula Oliveira (UNIRIO) Cunila MESH:Lamiaceae; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; MESH:Plant Growth Regulators; CHEBI:gibberellin; CHEBI:N-benzyladenine; MESH:In Vitro Techniques; MESH:Tissue Culture Techniques; ENVO:hydrophilic; NPO:lipophilic 2018-05
MTBLS582 MetaboLights Global Analyses of Selective Insulin Resistance in Hepatocytes due to Palmitate Lipotoxicity ZonWeng Lai (Harvard School of Public Health) Homo sapiens EFO:insulin resistance; CSEO:Lipidomics; EFO:Hepatic steatosis; GO:regulation of lipid biosynthetic process; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2018-04
MTBLS583 MetaboLights Identification of Metabolites and Transcripts Involved in Salt Stress and Recovery in Peanut Feng Cui (Biotechnology Research Center, Shandong Academy Of Agricultural Sciences) Arachis hypogaea untargeted metabolites; GO:response to salt stress; NCIT:Recovery; CHMO:gas chromatography-mass spectrometry; correlation analysis 2019-03
MTBLS584 MetaboLights Based on the Metabolomic Approach the Energy Metabolism Responses of Oriental River Prawn Macrobrachium nipponense Hepatopancreas to Acute Hypoxia and Reoxygenation Shengming Sun (Ferashwater Fisheries Research Center, Chinaese Academy of Fiaheries) Macrobrachium nipponense EFO:Oxidative Stress; transcriptomics; EFO:hypoxia; MTBLS:targeted metabolites; CHMO:gas chromatography time-of-flight mass spectrometry 2021-05
MTBLS587 MetaboLights Novel automated workflow for spectral alignment and mass calibration in MS imaging using a sputtered Ag nanolayer Pere RafolsSoler (Department of Electronic Engineering, Rovira i Virgili University, IISPV, Tarragona (Spain)) Mus musculus CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; MTBLS:Proof of Concept Study; BAO:method development and validation 2022-01
MTBLS588 MetaboLights Assessing the potential of sputtered gold nanolayers in mass spectrometry imaging for metabolomics applications (Brain MALDI-MSI assay) Pere RafolsSoler (Department of Electronic Engineering, Rovira i Virgili University, IISPV, Tarragona (Spain)) Mus musculus BAO:method development and validation; CHMO:magnetron sputter deposition; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry 2022-01
MTBLS586 MetaboLights Hepatic Metabolomics Investigation in Acute and Chronic Murine Toxoplasmosis Xiaoqing Chen (Lanzhou Veterinary Research Institute) Mus musculus EFO:toxoplasmosis; HINO:host-pathogen interaction; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; PW:metabolic disease pathway 2019-08
MTBLS589 MetaboLights Assessing the potentiality of sputtered gold nanolayers in mass spectrometry imaging for metabolomics applications (Liver MALDI-MSI assay) Pere RafolsSoler (Department of Electronic Engineering, Rovira i Virgili University, IISPV, Tarragona (Spain)) Mus musculus CHMO:magnetron sputter deposition; BAO:method development and validation; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; MTBLS:untargeted metabolites 2022-01
MTBLS596 MetaboLights Metabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine UPLC-MS assay) Emilien Jamin (Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRA, ENVT, INP Purpan, UPS, Toulouse, France) Mus musculus CHEBI:pesticide; EFO:diabetes mellitus; EFO:sexual dimorphism; MESH:constitutive androstane receptor; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; untargeted metabolites 2019-05
MTBLS591 MetaboLights A Prototypic Small Molecule Database for Bronchoalveolar Lavage-Based Metabolomics Scott Walmsley (UC Denver Anschutz Medical Campus) Homo sapiens BRO:Metabolomics Facility; NCIT:Chronic Obstructive Pulmonary Disease; NCIT:Bronchoalveolar Lavage Fluid; Sample Specific Databases; high-performance liquid chromatography-mass spectrometry; CHEBI:lipid; untargeted metabolites 2018-02
MTBLS593 MetaboLights Reactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis Ludgero Tavares (Center for Neurosciences and Cell Biology) Mus musculus EFO:adenocarcinoma; MESH:Respiratory Burst; EFO:colitis; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Lipidomics 2019-05
MTBLS599 MetaboLights Marine toxins spectral database for dereplication purpose Olivier Thomas (University of Galway) Alexandrium ostenfeldii::Azadinium spinosum::Gambierdiscus belizeanus OMIT:Marine toxins; MTBLS:ultra-performance liquid chromatography-mass spectrometry; PORO:Fragmentation; MTBLS:targeted metabolites; MTBLS:untargeted metabolites 2020-01
MTBLS600 MetaboLights Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease Mariona Jove (University of Lleida) Mus musculus EFO:Liver Disease; EFO:Non-Alcoholic Fatty Liver Disease; MTBLS:Mitofusin 2 (Mfn2); EFO:Non-Alcoholic Steatohepatitis; GAZ:Nash; MTBLS:high-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2018-01
MTBLS601 MetaboLights Metabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging mouse liver positive mode) Xiaotao Shen (Chinese Academy of Sciences) Mus musculus NCIT:Metabolomics; MetDNA; method development; metabolite annotation; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-03
MTBLS597 MetaboLights Automated, Parallel Mass Spectrometry Imaging and Structural Identification of Lipids Shane Ellis (Maastricht University) Rattus norvegicus::reference compound::Sus scrofa domesticus MS:matrix-assisted laser desorption ionization; EFO:brain; BTO:intestine; CHMO:imaging mass spectrometry; CHMO:tandem mass spectrometry; targeted metabolites; untargeted metabolites; NCIT:Lipidomics 2018-05
MTBLS606 MetaboLights Metabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging mouse liver negative mode) Xiaotao Shen (Chinese Academy of Sciences) Mus musculus SWO:Metabolomics; MetDNA; method development; metabolite annotation; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-03
MTBLS602 MetaboLights Metabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine, plasma and liver NMR assay) Sandrine ElleroSimatos (INRA) Mus musculus NCIT:Pesticide; EFO:diabetes mellitus; EFO:sexual dimorphism; MESH:constitutive androstane receptor; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2018-05
MTBLS598 MetaboLights Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty Nicholas Rattray (Yale University) Homo sapiens ONTOAD:Frailty; Carnitine transporters; tocotrienol; liquid chromatography-mass spectrometry; untargeted metabolites; targeted metabolites 2019-09
MTBLS612 MetaboLights Metabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging fruit fly positive mode) Xiaotao Shen (Chinese Academy of Sciences) Drosophila melanogaster NCIT:Metabolomics; MetDNA; method development; metabolite annotation; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-03
MTBLS607 MetaboLights Hypusination Orchestrates the Antimicrobial Response of Macrophages MWade Calcutt (Vanderbilt University / Mass Spectrometry Research Center) solvent blank::Mus musculus::Reference compound CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCBITAXON:Helicobacter pylori; CHEBI:polyamine; PW:innate immune response pathway; NCIT:Deoxyhypusine Synthase; UPaUPA:eIF5A hypusination; NCBITAXON:Citrobacter rodentium 2021-04
MTBLS608 MetaboLights Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs) Manuel Schlimpert (CF Metabolomics Centre for Bilogical Systems Analysis) blank::Reference compound::Mus musculus Direct cell reprogramming; Cellular identity; EFO:nephrotoxicity; MTBLS:untargeted metabolites; MTBLS:targeted metabolites; CHMO:gas chromatography-mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry 2021-08
MTBLS614 MetaboLights A lipidomic human population and translational feeding study of hepatic steatosis and de novo lipogenesis (Murine liver assay) Jules Griffin (Imperial College London) blank::Mus musculus CHMO:liquid chromatography-mass spectrometry; NCIT:Intervention or Procedure; untargeted metabolites; CSEO:Lipidomics 2018-03
MTBLS613 MetaboLights A metabolomic study of Gomphrena agrestis in Brazilian Cerrado suggests drought-adaptive strategies on metabolism Ilka Abreu (Dept. Plant Nutrition, Kiel University) Gomphrena MTBLS:untargeted metabolites; CCON:cerrado; CHMO:ultra-performance liquid chromatography-mass spectrometry; ENVO:drought; OMIT:Osmoregulation; MTBLS:oxidative damage; MTBLS:seasonality 2021-10
MTBLS615 MetaboLights Metabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging fruit fly negative mode) Xiaotao Shen (Chinese Academy of Sciences) Drosophila melanogaster NCIT:Metabolomics; MetDNA; method development; metabolite annotation; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-03
MTBLS618 MetaboLights Metabolomics of Solanum lycopersicum infected by Phytophthora infestans leads to Late blight detection and reveals metabolic differences in infection times PaulaLiliana Galeano (Universidad de los Andes) Solanum lycopersicum EFO:Phytophthora infestans; MESH:Phytophthora infestans; MESH:Multivariate Analysis; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; MESH:Host-Pathogen Interactions 2019-01
MTBLS616 MetaboLights A lipidomic human population and translational feeding study of hepatic steatosis and de novo lipogenesis (Human plasma assay) Jules Griffin (Imperial College London) Homo sapiens Direct Infusion Mass Spectrometry; NCIT:Intervention or Procedure; untargeted metabolites; CSEO:Lipidomics 2018-03
MTBLS619 MetaboLights Response to dietary carbohydrates in European seabass (Dicentrarchus labrax) muscle tissue as revealed by NMR-based metabolomics Ludgero Tavares (Center for Neurosciences and Cell Biology) Dicentrarchus labrax ENVO:aquaculture process; EFO:diet; EFO:carbohydrate; MESH:Muscle Development; untargeted metabolites; CHMO:magic angle spinning nuclear magnetic resonance spectroscopy 2019-01
MTBLS622 MetaboLights Elevated CO2 and virus infection impacts wheat and aphid metabolism Simone Vassiliadis (Department of Economic Development, Jobs, Transport and Resources (DEDJTR)) Rhopalosiphum padi::Triticum aestivum PEAO:virus plant treatment; CRISP:plant disease; NCBITAXON:Barley yellow dwarf virus-PAV; CHEBI:carbon dioxide; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; ENVO:climate change 2019-01
MTBLS628 MetaboLights Overexpression of vesicle-associated membrane protein PttVAP27-17 as a tool to improve biomass production and the overall saccharification yields in Populus trees Ilka Abreu (Dept. Plant Nutrition, Kiel University) Populus tremula x Populus tremuloides MTBLS:untargeted metabolites; MTBLS:vesicle-associated membrane protein; MTBLS:vap27; NCIT:Growth; MTBLS:bioprocessing; NCIT:Transcriptomics; NCIT:Proteomics; NCIT:Microtubule; CHMO:Ultra-performance liquid chromatography-mass spectrometry 2021-10
MTBLS627 MetaboLights Metabolic Changes of Maternal Uterine Fluid, Uterus, and Plasma during the Peri-implantation Period of Early Pregnancy in Mice TingLi Han (Chonginq Medical Universtiy) Mus musculus MTBLS:untargeted metabolites; CHMO:Gas chromatography mass spectrometry; ERO:Implantation; EFO:Pregnancy; GO:Decidualization 2020-05
MTBLS620 MetaboLights Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes: Type 1 Diabetes Prediction and Prevention Study (DIPP) Santosh Lamichhane (University of Turku) Homo sapiens EFO:diabetes mellitus; targeted metabolites; CSEO:Lipidomics; CHEBI:lipid; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-07
MTBLS623 MetaboLights Evaluation of sample preparation methods for NMR-based metabolomics of cow milk Bndict Yanibada (INRA) Bos taurus untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Nutrition; MESH:Food Analysis 2019-06
MTBLS624 MetaboLights Mapping the metabolism of five amino acids in bloodstream form Trypanosoma brucei using U-13C-labelled substrates and LC–MS Fiona Achcar (University of Glasgow) Medium::Trypanosoma brucei::Blank untargeted metabolites; targeted metabolites; NCIT:Amino Acid Metabolism Pathway; PLOSTHES:Parasitic protozoans; MESH:Trypanosoma; CHEBI:isotopic tracer; CHMO:liquid chromatography-mass spectrometry 2019-06
MTBLS626 MetaboLights Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the Myc-dependent metabolic reprogramming of stromal cells wei yan (ucsd) Homo sapiens::Mus musculus ACGT-MO:Metabolism; untargeted metabolites; MESH:Cancer-Associated Fibroblasts; CHMO:nuclear magnetic resonance spectroscopy; NCIT:MicroRNA; EFO:cancer; NCIT:Tracer 2018-07
MTBLS629 MetaboLights Flow cytometry has a significant impact on the cellular metabolome (General LC-MS assay) Aleksandra Binek (Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain) Mus musculus CHMO:fluorescence-activated cell sorting; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-11
MTBLS630 MetaboLights Genome-scale metabolic modelling of responses to polymyxins in Pseudomonas aeruginosa Yan Zhu (Monash University) Pseudomonas aeruginosa CHEBI:polymyxin; untargeted metabolites; CSEO:Lipidomics; genome-scale metabolic model; CHMO:high-performance liquid chromatography-mass spectrometry 2018-02
MTBLS631 MetaboLights Flow cytometry has a significant impact on the cellular metabolome (Lipidomic LC-MS assay) Aleksandra Binek (Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain) Mus musculus CHMO:fluorescence-activated cell sorting; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Lipidomics 2018-11
MTBLS633 MetaboLights Flow cytometry has a significant impact on the cellular metabolome (CE-MS assay) Aleksandra Binek (Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain) Mus musculus CHMO:fluorescence-activated cell sorting; CHMO:capillary electrophoresis-mass spectrometry; untargeted metabolites 2018-11
MTBLS634 MetaboLights Flow cytometry has a significant impact on the cellular metabolome (GC-MS assay) Aleksandra Binek (Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain) Mus musculus CHMO:fluorescence-activated cell sorting; untargeted metabolites; CHMO:gas chromatography-mass spectrometry 2018-11
MTBLS639 MetaboLights Alterations in the metabolic footprint induced by Mayaro virus infection in cell culture FabioRogerio deMoraes (Physcis Departament from the Institute for Biosciences, Language and Exact Sciences - State University of São Paulo) Chlorocebus aethiops NCIT:Viral Infection; SNOMED:Mayaro fever (disorder); MTBLS:untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; NCBITAXON:Mayaro virus 2021-10
MTBLS640 MetaboLights Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay) Ali Yilmaz (Research Fellow/ William Beaumont Research) Mus musculus targeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; EFO:biomarker; EFO:Parkinson's disease 2019-02
MTBLS641 MetaboLights Comprehensive High-Resolution Multiple-Reaction Monitoring Mass Spectrometry for Targeted Eicosanoid Assays Lucia Faccioli (Universidade de São Paulo - Faculdade de Ciências Farmacêuticas de Ribeirão Preto) reference compound CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:icosanoid; High-Resolution Multiple-Reaction Monitoring Mass Spectrometry; CSEO:Lipidomics; targeted metabolites; CHMO:tandem mass spectrometry 2018-06
MTBLS636 MetaboLights Molecular structural diversity of mitochondrial cardiolipins Gregor mer (Medical University Innsbruck) Escherichia coli::Saccharomyces cerevisiae::Dictyostelium discoideum::Drosophila melanogaster::Micrococcus luteus::Cricetulus griseus::Homo sapiens::Pseudomonas putida::Mus musculus::Bacillus drentensis::Oryza sativa::Sus scrofa::Danio rerio::Arabidopsis thaliana::Aspergillus fumigatus NCIT:Lipidomics; CHEBI:cardiolipin; EFO:Disorder of phospholipids, sphingolipids and fatty acids biosynthesis; MTBLS:Membrane lipid; CHMO:high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry; MTBLS:targeted metabolites 2021-01
MTBLS638 MetaboLights Metabolome variability for two Mediterranean sponge species of the genus Haliclona: specificity, time, and space Miriam Reverter (National University of Ireland Galway) Haliclona fulva::Haliclona mucosa::Haliclona mucosa;Haliclona fulva NCBITAXON:Haliclona; PORO:sponge; Interspecific variability; roleAFRL:spatio-temporal role; MTBLS:untargeted metabolites; NCIT:Natural Product; CHMO:ultra-performance liquid chromatography-mass spectrometry 2021-10
MTBLS642 MetaboLights Metabolomics analysis of the toxic effects of the production of lycopene and its precursors April Miguez (Georgia Institute of Technology) Escherichia coli CCONT:Escherichia coli; MESH:Metabolic Engineering; EDAM:Metabolomics; Lycopene; CHMO:two-dimensional gas chromatography; MTBLS:untargeted metabolites 2021-02
MTBLS650 MetaboLights Global untargeted serum metabolomic analyses nominate metabolic pathways responsive to loss of expression of the orphan metallo beta-lactamase, MBLAC1 SIMONA CODREANU (1966) Mus musculus CHMO:Ultra-Performance Liquid Chromatography-Mass Spectrometry; CHMO:tandem mass spectrometry; untargeted metabolites; NCIT:Beta-Lactamase; CHEBI:ceftriaxone; MESH:SWIP-10 protein, C elegans 2019-03
MTBLS644 MetaboLights Metabolic Phenotyping and Strain Characterisation of Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients Using Rapid Evaporative Ionisation Mass Spectrometry Simon Cameron (Imperial College London) Pseudomonas aeruginosa MTBLS:untargeted metabolites; NCIT:Lipidomics; GO:quorum sensing; MTBLS:Rapid Evaporative Ionisation Mass Spectrometry; EFO:cystic fibrosis 2022-01
MTBLS652 MetaboLights Infection-Induced Peroxisome Biogenesis Is a Metabolic Strategy for Herpesvirus Replication Pierre JeanBeltran (Princeton University) Homo sapiens Plasmalogen; Cytomegalovirus; CHMO:high-performance liquid chromatography; targeted metabolomics 2018-10
MTBLS648 MetaboLights Effect of Pro-longevity drugs on Lipid profile, link between lipid signalling and longevity TesfahunDessale Admasu (National University of Singapore) Caenorhabditis elegans CSEO:Lipidomics; BAO:drug; EFO:aging; CHMO:tandem mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry 2018-06
MTBLS653 MetaboLights A data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity Vronique PELLOUX (INSERM) Homo sapiens NCIT:Lifestyle Factors, Unspecified; NCIT:Insulin Sensitivity Measurement; ERO:OMICs data analysis objective; MESH:Microbiota 2021-02
MTBLS654 MetaboLights Role of jeotgal, a Korean traditional fermented fish sauce, in microbial dynamics and metabolite profiles during kimchi fermentation SeHee Lee (World Institute of Kimchi) Brassica rapa MEO:kimchi; MEO:jeotgal; NCIT:Fermentation; targeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; PLOSTHES:Lactic acid bacteria; Bacterial succession; Metabolite changes 2019-02
MTBLS662 MetaboLights Regulatory actors and alternative routes for Arabidopsis seed germination are revealed using a pathway‐based analysis of transcriptomic datasets Cantonny Valerie (IPS2) Arabidopsis thaliana untargeted metabolites; BIOMODELS:seed dormancy; CHMO:gas chromatography-mass spectrometry; BIOMODELS:seed germination 2019-05
MTBLS658 MetaboLights A robust intracellular metabolite extraction protocol for human neutrophil metabolic profiling MarieMargaret Phelan (University of Liverpool) Homo sapiens untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; EFO:rheumatoid arthritis 2018-12
MTBLS656 MetaboLights A Pilot Characterization of the Human Chronobiome Seth Rhoades (Vanderbilt University Medical Center) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; targeted metabolites; EFO:metabolomic profiling; EFO:replicate; EFO:circadian rhythm 2018-05
MTBLS661 MetaboLights Generation and characterization of thiol-deficient Mycobacterium tuberculosis mutants CARINE SAO (Stellenbosch Uiniversity) Mycobacterium tuberculosis::Mycobacterium bovis CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:thiol; NCIT:Gene Deletion; biosynthetic enzymes; CHMO:tandem mass spectrometry; EFO:Tuberculosis; targeted metabolites 2018-07
MTBLS666 MetaboLights Identification of amniotic fluid metabolomic and placental transcriptomic changes associated with abnormal development of cloned pig fetuses zheng Ao (National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China) Sus scrofa IOBC:somatic cell nuclear transplantation; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Artificial Insemination; CHMO:tandem mass spectrometry 2020-01
MTBLS667 MetaboLights Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice Jeremy Everett (University of Greenwich) Mus musculus EFO:aging; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2018-06
MTBLS669 MetaboLights Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations Suehelay Acevedo (University of Wisconsin-Madison) Homo sapiens NCIT:Ductal Breast Carcinoma In Situ; untargeted metabolites; CRISP:microfluidics; EFO:hypoxia; CHMO:nuclear magnetic resonance spectroscopy; DOID:breast cancer 2019-02
MTBLS665 MetaboLights MaHPIC Experiment HuC - Metabolomics of plasma samples from human volunteers infected with Plasmodium vivax Jessica Kissinger (Institute of Bioinformatics, University of Georgia) Homo sapiens::Homo sapiens;NCBITAXON:Plasmodium vivax NCIT:Malaria; Anti-malarial treatment; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2018-06
MTBLS664 MetaboLights MaHPIC Experiment HuB - Metabolomics analysis of human plasma from patients infected with Plasmodium falciparum and P.vivax for discovery of diagnostic markers of malaria Jessica Kissinger (Institute of Bioinformatics, University of Georgia) Homo sapiens;Plasmodium falciparum::Homo sapiens::blank::reference compound::Homo sapiens;Plasmodium vivax;Plasmodium falciparum::Homo sapiens;Plasmodium vivax NCIT:Malaria; Biocrates Absolute IDQp180 kit; CHMO:ultra-performance liquid chromatography-mass spectrometry; MS:flow injection analysis; untargeted metabolites; targeted metabolites 2018-09
MTBLS670 MetaboLights New plasma preparation approach to enrich metabolome coverage in untargeted metabolomics: plasma protein bound hydrophobic metabolite release with proteinase K Szymon Macioszek (Medical University of Gdansk, Department of Biopharmacy and Pharmacodynamics) Homo sapiens MTBLS:Proof of Concept Study; untargeted metabolomics; MS:sample preparation; CHMO:high-performance liquid chromatography-mass spectrometry; SNOMED:Proteinase K (substance) 2022-03
MTBLS673 MetaboLights Metabolomics Investigation of Dietary Effects on Flesh Quality in Grass Carp (Ctenopharyngodon idellus) Dapeng Li (College of Fisheries, Huazhong Agricultural University) Ctenopharyngodon idella SNOMEDCT:Sudan grass; Fish flesh quality; RADLEX:fat deposition; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2018-08
MTBLS675 MetaboLights Characterization of trotter horses urine metabolome by means of proton nuclear magnetic resonance spectroscopy Luca Laghi (Bologna University) Equus caballus untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2019-02
MTBLS674 MetaboLights Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays) Ali Yilmaz (Research Fellow/ William Beaumont Research) Mus musculus targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:biomarker; EFO:Parkinson's disease; MTBLS:flow injection analysis-mass spectrometry; CHMO:tandem mass spectrometry; MTBLS:Biocrates Absolute IDQp180 kit 2019-02
MTBLS678 MetaboLights Common Metabolic Pathways Implicated in Resistance to Chemotherapy Point to a Key Mitochondrial Role in Breast Cancer Sara Samino (URV-CIBERDEM) Homo sapiens::Culture Media NCIT:Cancer Biology; Chemoresistance; CHMO:nuclear magnetic resonance spectrometer; untargeted metabolites; EFO:breast cancer; NCIT:Mitochondrion; EFO:stem cell; NCIT:Autophagy; NCIT:Proteomics; NCIT:Antibiotic; NCIT:Cancer Stem Cell; NCIT:Cell Line 2019-08
MTBLS671 MetaboLights Semi‐polar root exudates in natural grassland communities Steffen Neumann (Leibniz Institute of Plant Biochemistry) Lolium perenne::Galium mollugo::Arrhenatherum elatius::Plantago lanceolata::Reference compound mix::Ranunculus acris::Alopecurus pratensis::Pooled sample::Dactylis glomerata::Poa pratensis::Sample preparation blank::Achillea millefolium::Galium verum SWO:Metabolomics; ENVO:grassland; BOF:Vegetation; plant functional traits; BOF:Environment; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2018-08
MTBLS677 MetaboLights Dissection of metabolic reprogramming in polycystic kidney disease reveals coordinated rewiring of bioenergetic pathways AnaSofia HenriquesdaCosta (Cold Spring Harbor Laboratory) Culture Media, Conditioned::Mus musculus::Culture Media CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:Polycystic Kidney Disease; CHEBI:isotopic tracer; CHEBI:carbon-13 atom; CHEBI:nitrogen-15 atom; targeted metabolites 2019-06
MTBLS676 MetaboLights Serum protein N-glycosylation changes in multiple myeloma Stephanie Holst (Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands) Homo sapiens EFO:multiple myeloma; MOP:N-glycosylation; CHMO:mass spectrometry; NCIT:Glycomics; GO:sialylation; MTBLS:untargeted metabolites; CHMO:matrix-assisted laser desorption-ionisation time-of-flight mass spectrometry; MOP:galactosylation; GO:fucosylation 2022-04
MTBLS680 MetaboLights Cyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine kidney and plasma UPLC-MS/MS assay) Cecilia Castro (University of Cambridge) Mus musculus untargeted meyabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:endothelium; NCIT:Pharmacology; nitric oxide; Prostaglandins 2019-08
MTBLS682 MetaboLights Molecular changes in cancer cells exposed to an HDAC inhibitor: A metabolomics approach Giovanny RodriguezBlanco (University of Edinburgh) Homo sapiens NCIT:Epigenomics; EFO:colorectal cancer; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:histone deacetylase inhibitor; CHMO:tandem mass spectrometry; MTBLS:untargeted metabolites 2022-05
MTBLS679 MetaboLights LC-MS based plant metabolic profiles of thirteen grassland species grown in diverse neighbourhoods Steffen Neumann (Leibniz Institute of Plant Biochemistry) blank::Anthoxanthum odoratum::Plantago lanceolata::Festuca rubra::Geranium pratense::QC_pool::Dactylis glomerata::Centaurea jacea::Holcus lanatus::Poa pratensis::Avenula pubescens::Leucanthemum vulgare::Phleum pratense::Knautia arvensis::Ranunculus acris MTBLS:untargeted metabolites; MTBLS:ultra-performance liquid chromatography-mass spectrometry; MTBLS:species diversity; MTBLS:community dynamics; CHEBI:Plant metabolite 2020-12
MTBLS685 MetaboLights Cyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay) Cecilia Castro (University of Cambridge) Mus musculus::Homo sapiens targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:endothelium; NCIT:Pharmacology; nitric oxide; Prostaglandins 2019-08
MTBLS683 MetaboLights Vegetable Signatures Derived from Human Urinary Metabolomic Data in Controlled Feeding Studies KeShiuan Lynn (Department of Mathematics, Fu Jen Catholic University, Taiwan) Homo sapiens untargeted metabolites; vegetable metabolome; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2019-05
MTBLS686 MetaboLights Croquemort elicits activation of the immune deficiency pathway in ticks Joao Pedra (University of Maryland School of Medicine) Ixodes scapularis CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; NCIT:CD36 Gene; PR:protein croquemort (fruit fly); NCIT:Lipidomics; EFO:Lyme disease; OMIT:Ticks; CHMO:tandem mass spectrometry 2023-04
MTBLS689 MetaboLights Non-invasive urinary metabolomic profiles discriminate biliary atresia from infantile hepatitis syndrome weiwei li (Affiliated Hospital of Nanjing University of Chinese Medicine) Homo sapiens untargeted metabolites; CHMO:gas chromatography-mass spectrometry; EFO:Biliary atresia; infantile hepatitis syndrome; EFO:biomarker 2019-06
MTBLS691 MetaboLights MaHPIC Experiment E03 - Quantitative Metabolomics of Macaca mulatta infected with Plasmodium coatneyi Hackeri strain to produce and integrate clinical, hematological, parasitological, and omics measures of acute, recrudescent, and chronic infections Jessica Kissinger (Institute of Bioinformatics, University of Georgia) Homo sapiens::Macaca mulatta;NCBITAXON:Plasmodium coatneyi::blank::reference compound NCIT:Malaria; MTBLS:Biocrates Absolute IDQp180 kit; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:flow injection analysis-mass spectrometry; MTBLS:targeted metabolites; CHMO:tandem mass spectrometry 2018-09
MTBLS687 MetaboLights Linking root exudates to functional plant traits Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arrhenatherum elatius::Achillea millefolium::Alopecurus pratensis::Galium verum::Poa pratensis::Galium mollugo::Plantago lanceolata::study reference pool::blank::Dactylis glomerata::Ranunculus acris::Lolium perenne SWO:Metabolomics; ENVO:grassland; ENVO:climate; ENVO:soil; plant functional traits; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2022-02
MTBLS692 MetaboLights COSY catalyzes trans-cis isomerization and lactonization in the biosynthesis of coumarins Ruben Vanholme (VIB-UGent Center for Plant Systems Biology) Arabidopsis thaliana untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; coumarin synthase; CHEBI:coumarins 2019-08
MTBLS690 MetaboLights Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type-2 diabetes Klev Diamanti (Department of Immunology, Genetics and Pathology, Uppsala University, Sweden) Homo sapiens Type 2 Diabetes Mellitus; MEDDRA:Pre-diabetes; MTBLS:targeted metabolites; MTBLS:untargeted metabolomics; MTBLS:CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:CHMO:gas chromatography-mass spectrometry 2018-10
MTBLS696 MetaboLights Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway Emilio Rivera (Vanderbilt University) Mus musculus LOINC:Macrophages; NCBITAXON:Helicobacter pylori; Innate immunity; SNMI:Cystathionine gamma-lyase; CHEBI:polyamine; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2020-05
MTBLS688 MetaboLights Employing fingerprinting of medicinal plants by means of LC-MS and machine learning for species identification task Dmitry Nazarenko (Lomonosov Moscow State University) Aronia melanocarpa::Ouret lanata::Arctium lappa::Eleutherococcus sessiliflorus::Betula pendula::Dioscorea caucasica::Salvia officinalis::Glycyrrhiza glabra::Acorus calamus::Cichorium intybus::Eleutherococcus senticosus::Calendula officinalis::Matricaria chamomilla::Panax ginseng::Ginkgo biloba::Anethum foeniculum::Oplopanax elatus::Mentha x piperita::Aralia elata::Valeriana officinalis::Frangula alnus::Sambucus nigra::Viburnum opulus::Tilia cordata::Taraxacum officinale::Pimpinella anisum::Tussilago farfara::Artemisia absinthium::Hypericum perforatum::Origanum vulgare::Linum usitatissimum::Heracleum sphondylium::Daucus carota::Prunus padus::Silybum marianum::Pinus sylvestris::Fragaria vesca::Echinacea purpurea::Angelica archangelica::Levisticum officinale::Equisetum arvense::Helichrysum arenarium::Melilotus officinalis::Helianthus tuberosus::Pimpinella saxifraga::Bupleurum aureum::Viola tricolor::Rosa majalis::Tanacetum vulgare::Populus balsamifera::Bergenia crassifolia::Potentilla erecta::Juniperus communis::Senna alexandrina::Humulus lupulus::Vaccinium myrtillus::Convallaria keiskei::Urtica dioica::Hedysarum neglectum::Rhamnus cathartica::Inula helenium::Thymus serpyllum::Bidens tripartita::Aegopodium podagraria::Plantago major::Astragalus propinquus::Coriandrum sativum::Rhodiola rosea::Althaea officinalis::Leonurus quinquelobatus::Asarum europaeum::Polemonium caeruleum::Anethum graveolens::Petroselinum crispum CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; plant species; NCIT:Machine Learning; MTBLS:Proof of Concept Study 2022-04
MTBLS698 MetaboLights Firefly genomes illuminate parallel origins of bioluminescence in beetles TimothyR Fallon (UCSD/SIO) Aquatica lateralis::Photinus pyralis::Ignelater luminosus untargeted metabolites; CHMO:liquid chromatography-mass spectrometry; NCIT:Bioluminescence 2018-09
MTBLS694 MetaboLights Investigation of cross-platform analytical precision in NMR and UPLC-MS based metabolic-phenotyping Jake Pearce (Imperial College London) Synthetic::Homo sapiens MATR:Source; cross-platform; CHMO:nuclear magnetic resonance spectroscopy; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolomics 2018-08
MTBLS697 MetaboLights Proteome allocations change linearly with the specific growth rate of Saccharomyces cerevisiae under glucose limitation Jianye XIA (Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences) Saccharomyces cerevisiae CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; MTBLS:Crabtree effect; OMIT:Allosteric Regulation; CHMO:tandem mass spectrometry 2022-08
MTBLS701 MetaboLights Identification of chemotypes in bitter melon by metabolomics: a plant with potential benefit for management of diabetes in traditional Chinese medicine Shuaizhen Zhou (University of Geneva, and Shanghai Institute of Materia Medica) Momordica charantia::reference compound CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Principal Component Analysis; Molecular Networking; CHMO:tandem mass spectrometry; CHEBI:triterpenoid; untargeted metabolites 2019-10
MTBLS699 MetaboLights A systems analysis with “simplified source-sink model” reveals metabolic reprogramming in a pair of source-to-sink organs during early fruit development in tomato by LED light treatments Mikiko Takahashi (RIKEN-csrs) Solanum lycopersicum::reference compound MTBLS:untargeted metabolites; light stress; CHMO:gas chromatography time-of-flight mass spectrometry 2018-09
MTBLS693 MetaboLights Quantitative trait loci analysis identifies a prominent gene involved in the production of fatty-acid-derived flavor volatiles in tomato Karolina Garbowicz (Max Planck Institute For Molecular Plant Physiology) Solanum lycopersicum x Solanum pennellii CSEO:Lipidomics; CHEBI:volatile organic compound; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Lipase; CHEBI:4-Decenal; NCIT:RNA Interference 2018-07
MTBLS703 MetaboLights Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Thalassiosira pseudonana study) Katherine Heal (University of Washington) Thalassiosira pseudonana EFO:cobalamin metabolic process; MESH:Diatoms; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-06
MTBLS704 MetaboLights Changes in Amino Acid and Acylcarnitine Plasma Profiles for Distinguishing Patients with Multiple Sclerosis from Healthy Controls Marat Kasakin (Institute of Chemical Biology and Fundamental Medicine) Homo sapiens DOID:multiple sclerosis; CHEBI:amino acid; CHEBI:O-acylcarnitine; CHMO:tandem mass spectrometry; OMIT:Dried Blood Spot Testing; MESH:Multivariate Analysis; MTBLS:Direct Infusion Mass Spectrometry 2022-05
MTBLS700 MetaboLights Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents Fazheng Ren (China Agricultural University) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; Untargeted metabolites; NCBITAXON:human gut metagenome; DOID:end stage renal disease; CHMO:solid-phase micro-extraction; CHMO:gas chromatography-mass spectrometry; targeted metabolites 2020-10
MTBLS706 MetaboLights Gluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei Julie Kovarova (University of Dundee) blank::Trypanosoma brucei::standard NCIT:Glycolysis/Gluconeogenesis Pathway; NCIT:Trypanosoma; BTO:kinetoplastid; NCIT:Fructose-1,6-Bisphosphatase 1; GO:glycosome; MESH:glucose transporter, Leishmania; RH-MESH:Parasitic Diseases; EFO:human african trypanosomiasis; CHMO:high-performance liquid chromatography-mass spectrometry; targeted metabolites; MTBLS:Glasgow Polyomics 2018-12
MTBLS702 MetaboLights Preterm birth is associated with xenobiotics and predicted by the vaginal metabolome Tal Korem (Columbia University) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; NCIT:Spontaneous Preterm Birth; NCIT:Ethnic Group; CHMO:tandem mass spectrometry 2022-11
MTBLS705 MetaboLights Inferring metabolic mechanisms of interaction within a defined gut microbiota Gregory Medlock (University of Virginia) Clostridium sp. asf356;Lactobacillus murinus asf361::Lactobacillus sp. asf360::Lactobacillus sp. asf360;Clostridium sp. asf502::Eubacterium plexicaudatum asf492;Clostridium sp. asf502::Blank sample::Lactobacillus sp. asf360;Eubacterium plexicaudatum asf492::Clostridium sp. asf356;Firmicutes bacterium asf500::Lactobacillus murinus asf361;Clostridium sp. asf502::Clostridium sp. asf356;Eubacterium plexicaudatum asf492::Lactobacillus murinus asf361;Eubacterium plexicaudatum asf492::Lactobacillus murinus asf361::Eubacterium plexicaudatum asf492;Firmicutes bacterium asf500::Firmicutes bacterium asf500;Lactobacillus murinus asf361::Lactobacillus sp. Asf360::Clostridium sp. asf356::Clostridium sp. asf356;Lactobacillus sp. asf360::Lactobacillus sp. asf360;Lactobacillus murinus asf361::Parabacteroides sp. Asf519::Clostridium sp. asf356;Lactobacillus murinus asf361;Parabacteroides sp. asf519::Eubacterium plexicaudatum asf492;Parabacteroides sp. asf519::Clostridium sp. asf502;Parabacteroides sp. asf519::Firmicutes bacterium asf500;Parabacteroides sp. asf519::Clostridium sp. asf356;Parabacteroides sp. asf519::Clostridium sp. asf356;Clostridium sp. asf502::Clostridium sp. asf502::Eubacterium plexicaudatum asf492::Lactobacillus murinus asf361;Firmicutes bacterium asf500::Firmicutes bacterium asf500;Clostridium sp. asf502::Firmicutes bacterium asf500::Lactobacillus sp. asf360;Parabacteroides sp. asf519::Lactobacillus murinus asf361;Parabacteroides sp. asf519::Lactobacillus sp. asf360;Firmicutes bacterium asf500::Parabacteroides sp. asf519 CCONT:microbiome; MESH:Gastrointestinal Microbiome; NCIT:Intestinal Flora; SWO:Microbial ecology; MESH:Microbial Interactions; ENVO:anaerobic; GMO:Anaerobic medium; MESH:Bacteria, Anaerobic 2019-10
MTBLS708 MetaboLights Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Navicula pelliculosa study) Katherine Heal (University of Washington) Fistulifera pelliculosa EFO:cobalamin metabolic process; MESH:Diatoms; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-06
MTBLS710 MetaboLights Software tool for internal standard based normalization of lipids, and effect of data-processing strategies on resulting values Jeremy Koelmel (Southeast Center for Integrated Metabolomics (SECIM)) blank::Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MS:lipidomics analysis software; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; MTBLS:SRM 1950; NCIT:Lipidomics; MTBLS:Proof of Concept Study 2022-05
MTBLS707 MetaboLights High metabolic variation for seaweeds in response to environmental changes: a case study of the brown algae Lobophora in coral reefs Julie GAUBERT (IRD) Lobophora monticola::Lobophora obscura::Lobophora sonderi::Lobophora rosacea CHMO:ultra-performance liquid chromatography-mass spectrometry; MS:6540 Q-TOF LC/MS; ADW:Macroalgae; ENVO:coral reef; GAZ:New Caledonia Barrier Reef 2019-09
MTBLS709 MetaboLights Chemical Diversity and Classification of Secondary Metabolites in Nine Bryophyte Species Kristian Peters (IPB Halle) Marchantia polymorpha s. l.::Plagiomnium undulatum::Calliergonella cuspidata::Quality control::Rhytidiadelphus squarrosus::Fissidens taxifolius::Polytrichum strictum::Grimmia pulvinata::Brachythecium rutabulum::Hypnum cupressiforme s. l. ECSO:Species; ECSO:season; PECO:metabolite 2019-12
MTBLS716 MetaboLights Evidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure MRCNIHR NationalPhenomeCentre (Imperial College) Canis lupus familiaris MTBLS:canine dog; MTBLS:untargeted metabolites; CHMO:Ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Lipidomics; EFO:heart disease; EFO:heart failure; MTBLS:mitral 2022-03
MTBLS711 MetaboLights Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial MRCNIHR NationalPhenomeCentre (Imperial College) Homo sapiens MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:nuclear magnetic resonance spectroscopy; CHMO:tandem mass spectrometry 2025-02
MTBLS720 MetaboLights Skeletal muscle metabolomics and blood biochemistry analysis reveal metabolic changes associated with dietary amino acid supplementation in dairy calves Kuai Yu (Universitat Autonoma de Barcelona) Bos taurus RCD:Amino acid supplementation; calf growth; ATC:Milk substitutes; LOINC:Skeletal muscle; blood biochemistry; CHMO:nuclear magnetic resonance spectroscopy; untargeted metabolites 2018-10
MTBLS721 MetaboLights Multi-hierarchical profiling the structure-activity relationships of engineered nanomaterials at nano-bio interfaces Xiaoming Cai (Soochow University) blank::Homo sapiens HINO:The NLRP3 inflammasome; BAO:structure activity relationship analysis; untargeted metabolites; EFO:immortal cell line cell; CHEBI:maghemite nanoparticle; ultra-fast liquid chromatography-mass spectrometry 2020-01
MTBLS722 MetaboLights Untargeted LC-MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase Lucas Chibli (University of São Paulo (USP)) Anteremanthus hatschbachii::Tridax procumbens::Sphagneticola trilobata::Arctium lappa::Artemisia annua::Dasyphyllum::Chresta pycnocephala::Lychnophora salicifolia::Calea::Tanacetum parthenium::Acmella oleracea::Chresta exsucca::Chresta::Achyrocline satureioides::Pluchea::Emilia sonchifolia::Matricaria chamomilla::Lychnophora mello-barretoi::Eremanthus goyazensis::Lychnophora santosii::Achillea millefolium::Chronopappus bifrons::Chuquiraga spinosa::Chresta plantaginifolia::Lactuca sativa::Paralychnophora atkinsiae::Vernonanthura::Sonchus oleraceus::Gymnanthemum amygdalinum::Baccharis::Artemisia absinthium::Aldama::Piptolepis monticola::Stevia rebaudiana::Cichorium intybus::Mikania cordifolia::Eremanthus polycephalus::Ageratum conyzoides::Eremanthus capitatus::Cynara::Blanchetia heterotricha::Solidago::Eremanthus argenteus::Echinacea purpurea::Mikania::Smallanthus sonchifolius::Heterocoma gracilis::Arnica montana::Taraxacum officinale::Soaresia velutina::Bidens pilosa::Schlechtendalia luzulifolia PR:dihydroorotate dehydrogenase (quinone); untargeted metabolites; EFO:Leishmania major; CHMO:ultra-performance liquid chromatography-mass spectrometry; MESH:Neglected Diseases 2019-10
MTBLS723 MetaboLights CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury Justine Leenders (University of Liège) Mus musculus GO:CXCL12-activated CXCR4 signaling pathway; CHMO:nuclear magnetic resonance spectroscopy; EFO:Danio rerio; NCIT:Knock-Out Mouse; EFO:ischemia reperfusion injury; EDAM:Gene expression profile; untargeted metabolites 2018-10
MTBLS724 MetaboLights Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness Russell Pickford (University of New South Wales) Drosophila melanogaster CHMO:gas chromatography-mass spectrometry; untargeted metabolites; NCIT:Diet; EFO:third instar larva stage 2018-11
MTBLS718 MetaboLights Antiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19 MRCNIHR NationalPhenomeCentre (Imperial College) Homo sapiens MTBLS:untargeted metabolites; DOID:COVID-19; OGG:CMPK2; OGG:SPATS2L; OGG:IFI27; OGG:RSAD2; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; CHEBI:biomarker; NCIT:Lipidomics 2022-02
MTBLS717 MetaboLights Direct on-swab metabolic profiling of vaginal microbiome:host interactions during pregnancy and preterm birth MRCNIHR NationalPhenomeCentre (Imperial College) blank::Homo sapiens::reference compound MTBLS:untargeted metabolites; MTBLS:desorption electrospray ionisation mass spectrometry; NCIT:Cervicovaginal Secretion; NCIT:Swab; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Preterm Birth; NCIT:Microbiome; GO:immune response; MTBLS:BioSamples 2021-09
MTBLS733 MetaboLights Comprehensive evaluation of untargeted metabolomics data processing software in feature detection, quantification and discriminating marker selection yan lu (shanghaitech university) Piper nigrum CHMO:high-performance liquid chromatography-mass spectrometry; MS:data processing software; NCIT:Comparative Marker Selection; untargeted metabolites; MS:MZmine; MS-Dial; MS:XCMS; MS:MarkerView Software; MS:Compound Discoverer 2019-11
MTBLS719 MetaboLights Metabolic phenotyping of urine from a dementia research cohort MRCNIHR NationalPhenomeCentre (Imperial College) blank::Homo sapiens MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:nuclear magnetic resonance spectroscopy; MTBLS:Urine global profiling; NCIT:Alzheimer's Disease; CHMO:tandem mass spectrometry 2022-03
MTBLS726 MetaboLights Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice Tom Metz (Pacific Northwest National Laboratory) Mus Musculus EFO:Microbiome; CHMO:Gas Chromatography Mass Spectrometry; CHMO:nuclear magnetic resonance spectroscopy; EFO:Autism Spectrum Disorder; untargeted metabolites 2019-07
MTBLS727 MetaboLights Rabbit plasma metabolomic analysis of Nitroproston: a multi target natural prostaglandin based-drug (Untargeted study) Ksenia Shestakova (Sechenov University) Oryctolagus cuniculus OBCS:soft independent modeling of class analogy analysis; MESH:Multivariate Analysis; untargeted metabolites; SNOMEDCT:Prostaglandin receptor; SNOMEDCT:Prostaglandin measurement; EFO:asthma; CHMO:ultra-performance liquid chromatography-mass spectrometry; Nitroproston 2019-08
MTBLS736 MetaboLights Comprehensive evaluation of untargeted metabolomics data processing software in feature detection, quantification and discriminating marker selection (AB SCIEX TripleTOF 6600 assay) yan lu (shanghaitech university) Piper nigrum MS:Data processing software; NCIT:Comparative marker selection; CHMO:Ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MS:Mzmine; MTBLS:MS-Dial; MS:Xcms; MS:Markerview software; MS:Compound discoverer 2019-11
MTBLS730 MetaboLights Aberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma (Xenograft assays) Rossella Galli (San Raffaele Scientific Institute) Homo sapiens::Mus musculus NCIT:Glioblastoma; GO:fucosylation; NCIT:Mesenchymal Glioblastoma; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MTBLS:Metabolon; NCIT:Proteomics; CHMO:tandem mass spectrometry 2022-11
MTBLS729 MetaboLights Persistent Alterations in Plasma Lipid Profiles Before Introduction of Gluten in the Diet Associated With Progression to Celiac Disease Partho Sen (Turku Center for Biotechnology, University of Turku) Homo sapiens EFO:celiac disease; MS:lipidomics analysis software; NCIT:Lipidomics; Metabolomics; lipid metabolism disorder; lipid metabolism disease pathway; abnormal lipid metabolism; Triglycerides; ultra-performance liquid chromatography-mass spectrometry; tTGA; gluten; Endoscopy; breast milk; genotype; Gluten free diet; Gender; MTBLS:untargeted metabolites 2020-01
MTBLS735 MetaboLights Time-resolved decoding of metabolic signatures of in vitro growth of the hemibiotrophic pathogen Colletotrichum sublineolum Fidele Tugizimana (University of Johannesburg) Colletotrichum sublineola CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; ENVO:Fungi; KISAO:partial least squares regression method; CHMO:principal components analysis dimensionality reduction; CCONT:time series design; BAO:gene expression 2022-05
MTBLS737 MetaboLights Metabolic Footprinting of a Clear Cell Renal Cell Carcinoma in vitro Model for Human Kidney Cancer Detection Malena Manzi (CIBION-CONICET) Homo sapiens::Culture Media::solvent::reference compound HP:Clear cell renal cell carcinoma; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2018-11
MTBLS738 MetaboLights Glycoalkaloid composition explains variation in slug resistance in Solanum dulcamara OnnoW Calf (Radboud University) Solanum dulcamara EFO:metabolomic profiling; CHMO:quadrupole time-of-flight mass spectrometry; MTBLS:Chemical diversity; BOF:Plant; MTBLS:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2019-06
MTBLS739 MetaboLights Integrated Proteomics and Metabolomics Analysis Reveals Differential Lipid Metabolism in HUVEC under high and low shear stress Gabriela Venturini (University of Sao Paulo) Homo sapiens EFO:shear stressing; ORDO:low density lipoprotein receptor; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2019-07
MTBLS744 MetaboLights Spatial metabolomics of in situ, host-microbe interactions (MALDI imaging MS assay) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Bathymodiolus puteoserpentis untargeted metabolites; SNOMEDCT:Marine mollusk; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; MESH:Symbiosis; NCIT:In Situ Hybridization; Fluorescence In Situ Hybridization 2019-11
MTBLS740 MetaboLights Quantitative metabolomic analysis of changes in the lens and aqueous humor under development of age-related nuclear cataract Vadim Yanshole (ITC SB RAS) Homo sapiens MTBLS:untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Nuclear Cataract 2022-11
MTBLS745 MetaboLights Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction Yue Qi (City of Hope) Homo sapiens Untargeted metabolites; EFO:breast cancer; arginine starvation; NCIT:Citrate Cycle (TCA Cycle) Pathway; NCIT:Cell Line; CHMO:liquid chromatography-mass spectrometry 2019-11
MTBLS746 MetaboLights Spatial metabolomics of in situ, host-microbe interactions (UPLC-MS/MS assay) Manuel Liebeke (Max Planck Institute of Marine Microbiology) control::Bathymodiolus sp. NZ3::Bathymodiolus thermophilus::Bathymodiolus heckerae::Bathymodiolus azoricus::Bathymodiolus antarcticus::Bathymodiolus manusensis::Bathymodiolus childressi::blank::Bathymodiolus mauritanicus::Gigantidas gladius::Bathymodiolus puteoserpentis::Bathymodiolus brooksi SNOMEDCT:Marine mollusk; untargeted metabolites; MESH:Symbiosis; NCIT:In Situ Hybridization; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2019-11
MTBLS742 MetaboLights Metabolome-based prediction of yield heterosis contributes to the breeding of elite rice Zhiwu Dan (Wuhan University) Oryza sativa FOODON:hybrid rice plant; OMIT:Seedlings; CHMO:liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2019-12
MTBLS750 MetaboLights Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy Ivan Nemazanyy (SFR Necker Inserm US 24 - CNRS UMS 3633) Mus musculus EFO:myopathy; targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; BTO:skeletal muscle; EFO:Endoplasmic Reticulum Stress 2019-01
MTBLS748 MetaboLights Untargeted gas chromatography–mass spectrometry-based metabolomics analysis of kidney and liver tissue from the Lewis Polycystic Kidney rat Hayley Abbiss (Murdoch University) Rattus norvegicus MTBLS:untargeted metabolites; CHMO:gas chromatography-mass spectrometry; EFO:Polycystic Kidney Disease; DOID:nephronophthisis 2023-01
MTBLS743 MetaboLights Postprandial Metabolism is Impaired in Overweight Normoglycemic Young Adults without Family History of Diabetes Aneesh Kumar (RGCB) Homo sapiens Type 2 Diabetes Mellitus; Asian Indian; lipid profiling; bile acid; ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-03
MTBLS751 MetaboLights Comparative metabolomics and transcriptomics revealed multiple pathways associated with polymyxin killing in Pseudomonas aeruginosa MeiLing Han (Monash University) Pseudomonas aeruginosa::standard CHEBI:polymyxin; MTBLS:Cross-omics; EDAM:Transcriptomics; CHMO:high-performance liquid chromatography-mass spectrometry; CHEBI:antibiotic; OMIT:Drug Resistance; MTBLS:untargeted metabolites 2018-11
MTBLS753 MetaboLights Gut Microbial and Metabolic Responses to Salmonella enterica Serovar Typhimurium and Candida albicans Caitlin Keller (University of Wisconsin-Madison) Mus musculus EFO:microbiome; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCBITAXON:Salmonella; NCBITAXON:Candida albicans; MTBLS:untargeted metabolites 2019-09
MTBLS752 MetaboLights Untargeted food contaminant detection using UHPLC-HRMS combined with multivariate analysis: Feasibility study on tea (Dataset 1 - Development) Mathieu Cladiere (AgroParisTech) Camellia sinensis::blank CHMO:spiking; CHEBI:environmental food contaminant; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; NCIT:Food Safety; MS:XCMS 2018-10
MTBLS755 MetaboLights Organic and Peptidyl Constituents of Snake Venoms: The Picture Is Vastly More Complex Than We Imagined Alejandro VillarBriones (Okinawa Institute of Science and Technology) Bothrops moojeni::Daboia siamensis::Cerastes cerastes::Bungarus multicinctus::Protobothrops elegans::Protobothrops flavoviridis::Crotalus viridis::Micrurus surinamensis::Micrurus spixii::Ophiophagus hannah::Agkistrodon piscivorus::Ovophis okinavensis::Dendroaspis polylepis::Naja kaouthia::Crotalus durissus CHMO:ultra-performance liquid chromatography-mass spectrometry; UBERON:snake venom; MTBLS:untargeted metabolites; CHEBI:peptide; CHEBI:purine nucleoside; XLMOD:purine base; CHEBI:neurotransmitter; MTBLS:neuromodulator; MTBLS:guanidinium compounds; CHEBI:carboxylic acid; CHEBI:amine; CHEBI:disaccharide; CHEBI:monosaccharide; CHEBI:amino acid 2023-01
MTBLS749 MetaboLights Alterations in the tyrosine and phenylalanine pathways revealed by biochemical profiling in cerebrospinal fluid of Huntington’s disease subjects Stephanie Herman (Uppsala University) Homo sapiens HRDO:Huntingtin (Huntington disease); MTBLS:untargeted metabolites; CHMO:Liquid Chromatography Mass Spectrometry 2019-06
MTBLS754 MetaboLights Untargeted food contaminant detection using UHPLC-HRMS combined with multivariate analysis: Feasibility study on tea (Dataset 2 - Validation) Mathieu Cladiere (AgroParisTech) blank::Camellia sinensis CHMO:spiking; CHEBI:environmental food contaminant; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; NCIT:Food Safety; MS:XCMS 2018-10
MTBLS756 MetaboLights Differentiation of Ficus deltoidea varieties and chemical marker determination by UHPLC-HRMS metabolomics for establishing quality control criteria of this medicinal herb Adlin Afzan (Researcher/Institute for Medical Research) Ficus deltoidea untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; MESH:Solid Phase Extraction 2019-01
MTBLS757 MetaboLights LION-web validation lipidomics experiments (FA-incorporation, membrane fluidty) Martijn Molenaar (Utrecht University) Cricetulus griseus NCIT:Lipidomics; MS:lipidomics analysis software; untargeted metabolites; EFO:immortal cell line cell 2019-04
MTBLS758 MetaboLights Metabolomics-derived marker metabolites to characterize Phaeocystis pouchetii in natural plankton communities Constanze Kuhlisch (Friedrich-Schiller University Jena) Phaeocystis pouchetii CHMO:gas chromatography-mass spectrometry; EFO:biomarker; meta memetabolomics; MTBLS:endometabolome; MTBLS:exometabolome; MTBLS:Arctic food web; ENVO:algal bloom 2020-06
MTBLS762 MetaboLights Targeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention Yan Bingpeng (The university of Hong Kong) Homo sapiens CHEBI:lipid; BAO:antiviral drug; PR:sterol regulatory element-binding protein; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2018-11
MTBLS760 MetaboLights Volatilomic insight of head and neck cancer via the effects observed on saliva metabolites Ravindra Taware (National Centre for Cell Science) Homo sapiens EFO:head and neck carcinoma; CHEBI:volatile organic compound; CHMO:gas chromatography-mass spectrometry; CHMO:headspace solid-phase micro-extraction; Non-invasive monitoring; untargeted metabolites 2019-06
MTBLS767 MetaboLights In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (GC- and LC-MS assays) Guy Schleyer (Weizmann Institute of Science) Emiliania huxleyi ADW:Phytoplankton; GO-EXT:virus-host interaction; CHMO:tandem mass spectrometry; CHMO:gas chromatography-mass spectrometry; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CRISP:plaque assay 2018-11
MTBLS761 MetaboLights Selective galactose culture condition reveals distinct metabolic signatures in pyruvate dehydrogenase and complex I deficient human skin fibroblasts Damian Hertig (Institute of Clinical Chemistry, University Hospital Bern, Bern, Switzerland) Homo sapiens CHEBI:galactose; CHMO:magic angle spinning nuclear magnetic resonance spectroscopy; untargeted metabolites 2021-10
MTBLS769 MetaboLights In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (Imaging MS assays) Guy Schleyer (Weizmann Institute of Science) Emiliania huxleyi untargeted metabolites; ADW:Phytoplankton; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; GO-EXT:virus-host interaction; CRISP:plaque assay; Liquid Microjunction-Surface Sampling Probe/Electrospray Ionization imaging mass spectrometry 2018-11
MTBLS768 MetaboLights Resolving coral photoacclimation dynamics through coupled photophysiological and metabolomic profiling unnikrishnan Kuzhiumparambil (UTS) Acropora muricata CHMO:high-performance liquid chromatography-mass spectrometry; untargeted metabolites; ENVO:coral reef; Light acclimation; GAZ:Great Barrier Reef; NCIT:Photosynthesis 2019-04
MTBLS763 MetaboLights A multiplatform metabolomic approach to characterize fecal signatures of stressful postnatal events in chicks: a pilot study Stéphane Beauclercq (Université du Québec à Montréal) Gallus gallus NCIT:Broiler Chicken; Chick; Postnatal stressful events; NCIT:Stress; NCIT:Metabolomics; CHMO:gas chromatography-mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-04
MTBLS770 MetaboLights Metabolomic signature of mouse cerebral cortex following Toxoplasma gondii infection Junjun He (CAAS) Mus musculus untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; SYMP:behavioral symptom; EFO:parasitic infection; NCBITAXON:Toxoplasma gondii 2020-04
MTBLS771 MetaboLights Untargeted food chemical safety assessment: A proof-of-concept on two analytical platforms and contamination scenarios of tea (Green tea study) Mathieu Cladiere (AgroParisTech) acetonitrile::Camellia sinensis CHMO:spiking; CHEBI:environmental food contaminant; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; NCIT:Food Safety 2019-02
MTBLS772 MetaboLights Untargeted food chemical safety assessment: A proof-of-concept on two analytical platforms and contamination scenarios of tea (Black tea study) Mathieu Cladiere (AgroParisTech) Camellia sinensis::acetonitrile CHMO:spiking; CHEBI:environmental food contaminant; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; NCIT:Food Safety 2019-02
MTBLS777 MetaboLights Comparative Analyses of Metabolomic Fingerprints and Cytotoxic Activities of Soft Corals from the Colombian Caribbean liliana santacruz (univesrity of sabana) Eunicea tayrona::Plexaurella nutans::Plexaurella::Eunicea fusca::Eunicea knightii::Pseudoplexaura flagellosa::Plexaura homomalla::Plexaura kukenthali::Plexaurella fusifera::Eunicea clavigera::Pseudopterogorgia albatrossae::Eunicea flexuosa::Eunicea::Eunicea asperula::Plexaura::Eunicea succinea untargeted metabolites; CHEBI:coral metabolite; NCIT:Cytotoxic Chemotherapy; CHEBI:diterpene; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2018-11
MTBLS779 MetaboLights Comparative analysis of proteomic and metabolomic profiles of different species of Paris feng liu (NCBA) Paris fargesii::Paris polyphylla CHMO:Gas chromatography time-of-flight mass spectrometry; EFO:Traditional chinese medicine type; EFO:Rheumatoid arthritis; untargeted metabolites 2020-01
MTBLS775 MetaboLights Metabolic profiling with UPLC-MS orbitrap of diatoms Coscinodiscus granii infected with parasitic oomycete Lagenisma coscinodisci Marine Vallet (Max Planck Institute for Chemical Ecology) Coscinodiscus granii;Lagenisma coscinodisci::Coscinodiscus granii::reference compound::Culture Media Parasitoid oomycetes; Diatoms; Lagenisma Coscinodisci; Beta-Carbolines; Ultra-Performance Liquid Chromatography-Mass Spectrometry; untargeted metabolites 2019-09
MTBLS781 MetaboLights RANCM: a new ranking scheme for assigning confidence levels to metabolite assignments in NMR-based metabolomics studies William Joesten (Miami University) Mus Musculus untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; PLOSTHES:Ranking algorithms 2019-09
MTBLS773 MetaboLights Application of HPLC-PDA-MS metabolite profiling to investigate the effect of growth temperature and day length on blackcurrant fruit JamesWilliam Allwood (James Hutton Institute) blank::Ribes nigrum untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; CHEBI:flavonoids; CHEBI:anthocyanin; CHEBI:flavonols; ENVO:climate; EFO:temperature; EFO:short day length regimen; EFO:long day length regimen; CHMO:tandem mass spectrometry 2019-02
MTBLS774 MetaboLights Imidazole ketone erastin induces ferroptosis and slows tumor growth in a mouse lymphoma model Fereshteh Zandkarimi (Columbia University) Matrix::Solvent Blank::Homo sapiens/Mus Musculus Xenograft::Homo sapiens GO:ferroptosis; BAO:lymphoma; NCIT:Lipidomics; MTBLS:untargeted metabolites 2019-04
MTBLS784 MetaboLights LC-MS untargeted approach showed that methyl jasmonate application on Vitis labrusca L. grapes increases phenolics at subtropical Brazilian regions Las Moro (USP) Vitis Labrusca::experimental blank Vitis Labrusca L.; PECO:methyl jasmonate exposure 2020-05
MTBLS787 MetaboLights Correlation-based Deconvolution (CorrDec) to generate high quality MS2 spectra from data independent acquisition in multi-sample studies (Chemical standards assay) Romanas Chaleckis (Nagoya City University) Homo sapiens CHMO:liquid chromatography-mass spectrometry; untargeted metabolites; Chemical standards characterisation; CHMO:tandem mass spectrometry 2020-07
MTBLS780 MetaboLights Linking genetic, metabolic and phenotypic diversity 1 among S. cerevisiae strains using multi-omics associations Kang Kang (Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute) Saccharomyces cerevisiae MCCV:Strain; multi-omic; Platform strain; FYPO:resistance to stress; Geno-to-phenotype association 2019-01
MTBLS789 MetaboLights Metabolic effects of an aspartate aminotransferase-inhibitor on two T-cell lines Magnus Sellstedt (Umeå University) Homo sapiens BAO:mode of action; SNOMEDCT:Aminotransferase inhibitor; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2018-12
MTBLS794 MetaboLights Multi‐omics identify xanthine as a pro‐survival metabolite for nematodes with mitochondrial dysfunction Antonia Piazzesi (DZNE) Caenorhabditis elegans EFO:Mitochondrial disease; targeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; insulin/IGF‐1 signaling; CHEBI:xanthine 2019-02
MTBLS788 MetaboLights Small Polar Hits against S. aureus: Screening, Initial Hit Optimization, and Metabolomic Studies Isabel Vincent (University of Glasgow) Staphylococcus aureus NCIT:Drug Discovery; untargeted metabolites; CHMO:liquid chromatography-mass spectrometry; MTBLS:Glasgow Polyomics 2021-11
MTBLS797 MetaboLights Bluebell saponins: Application of metabolomics and molecular networking RuAngelie EdradaEbel (Strathclyde University) blank::Hyacinthoides non-scripta untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; EFO:trypanosomiasis 2019-03
MTBLS790 MetaboLights Prolonged fasting times reap greater geroprotective effects when combined with caloric restriction in adult female mice Michel Bernier (National Institute on Aging, National Institutes of Health) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; EFO:response to low calorie diet; XCO:restricted feeding; OMP:lifespan phenotype; OBI:agglomerative hierarchical clustering; CHMO:tandem mass spectrometry 2024-05
MTBLS795 MetaboLights Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency CatherineR Dufour (McGill University - Goodman Cancer Institute) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; EFO:dilated cardiomyopathy; EDAM:Systems biology; NCIT:Phosphoproteome; EFO:transcriptome; TXPO:mitochondrial dysfunction; CHMO:tandem mass spectrometry 2022-09
MTBLS806 MetaboLights Ovothiol A is the Main Antioxidant in Fish Lens Vadim Yanshole (ITC SB RAS) Rutilus rutilus::Sander lucioperca targeted metabolites; CHEBI:ovothiol A; PLOSTHES:Freshwater fish; CHMO:nuclear magnetic resonance spectroscopy; EFO:antioxidant 2019-07
MTBLS805 MetaboLights Spatial metabolomics of in situ, host-microbe interactions (On-tissue MALDI imaging MS/MS assay) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Bathymodiolus puteoserpentis SNOMEDCT:Marine mollusk; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; MESH:Symbiosis; NCIT:In Situ Hybridization; CHMO:tandem mass spectrometry; targeted metabolites 2019-11
MTBLS803 MetaboLights The unique composition of Indian gut microbiome, gene catalogue and associated faecal metabolome deciphered using multi-omics approaches Darshan Dhakan (PhD) Homo sapiens EFO:gut microbiome measurement; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2019-01
MTBLS807 MetaboLights Drying Enhances Signal Intensities for Global GC–MS Metabolomics Manuel Liebeke (Max Planck Institute of Marine Microbiology) Saccharomyces cerevisiae::Lumbricus terrestris L2::Homo sapiens::reference compound::Posidonia oceanica CRISP:method development; untargeted metabolites; CHMO:gas chromatography-mass spectrometry 2019-04
MTBLS802 MetaboLights Circulating Metabolites in Progression to Islet Autoimmunity and Type 1 Diabetes Santosh Lamichhane (University of Turku) Homo sapiens NCIT:Type 1 Diabetes Mellitus; MTBLS:untargeted metabolites; CHMO:two-dimensional chromatography-mass spectrometry; EFO:autoimmune disease; OBI:longitudinal data analysis; MS:time-of-flight; NCIT:Newborn 2022-01
MTBLS804 MetaboLights Rapid UHPLC-MS metabolite profiling and phenotypic assays reveal genotypic impacts of nitrogen supplementation in oats JamesWilliam Allwood (James Hutton Institute) Avena sativa::blank CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:nitrogen molecular entity; TAXRANK:bio-variety; PTO:grain quality trait; CHEBI:beta-D-glucan; CHEBI:amino acid; NCIT:Lipidomics; Avenanthramides 2020-06
MTBLS808 MetaboLights Omics analysis in truffle (Tuber magnatum Pico): comparison of samples from different regions of Italy and from different seasons Federico Vita (University of Florence) Tuber magnatum CHMO:gas chromatography-mass spectrometry; CHMO:two-dimensional gas chromatography; CHMO:headspace solid-phase micro-extraction; MTBLS:liquid chromatography-tandem mass spectrometry; MTBLS:untargeted metabolites; CHMO:proton transfer reaction mass spectrometry; NCIT:Proteomics; MTBLS:food authenticity; CHEBI:volatile organic compound 2020-12
MTBLS798 MetaboLights A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease Wolfram Gronwald (University of Regensburg) Homo sapiens untargeted metabolomics; EFO:chronic kidney disease; CHMO:nuclear magnetic resonance spectroscopy 2019-07
MTBLS809 MetaboLights Plasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics zhengzhong luo (Sichuan Agricultural University/Veterinary Medicine College) Bos taurus untargeted metabolites; NCIT:Labor and Delivery Process; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Metabolic Response 2019-08
MTBLS811 MetaboLights Spatial metabolomics of in situ, host-microbe interactions (MRMS assay) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Bathymodiolus brooksi SNOMEDCT:Marine mollusk; untargeted metabolites; CHMO:Fourier transform ion cyclotron resonance mass spectrometry; CHMO:tandem mass spectrometry; MESH:Symbiosis; NCIT:In Situ Hybridization 2019-11
MTBLS801 MetaboLights Metabolic responses of rice cultivars with different tolerance to combined heat and drought stress under field conditions LovelyMae Lawas (Max Planck Institute of Molecular Plant Physiology) Oryza sativa::Chemical::non-sample-control PTO:drought tolerance; EFO:heat tolerance; GRO-CPGA:flower; GRO-CPD:06-flag leaf visible; EFO:developing seed stage; CHMO:gas chromatography-mass spectrometry; untargeted metabolites 2019-04
MTBLS812 MetaboLights Unravelling altered RNA metabolism in pancreatic cancer cells by liquid-chromatography coupling to ion mobility mass spectrometry Simon Lagies (Center for biological systems analysis, University of Freiburg) Homo sapiens::blank CHMO:ion mobility spectrometry-mass spectrometry; DOID:pancreatic cancer; GRO:RNA metabolism; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2019-05
MTBLS814 MetaboLights A multi-omic profiles of fruits regarding the maturation of Olive (Olea europaea L.) (Polyphenols UPLC-MS assay) Guodong Rao (Research Institute of Forestry, Chinese Academy of Forestry) Olea europaea targeted metabolites; CHEBI:flavonoid; CHMO:ultra high performance liquid chromatography 2019-05
MTBLS821 MetaboLights MaHPIC Experiment 30: Quantitative Metabolomics from the pilot experiment for Macaca mulatta infected with Plasmodium knowlesi Malayan strain sporozoites to produce and integrate clinical, hematological, parasitological, omics, telemetric and histopathological measures of acute primary infection Jessica Kissinger (Institute of Bioinformatics, University of Georgia) blank::reference compound::Macaca mulatta;NCBITAXON:Plasmodium knowlesi::Homo sapiens NCIT:Malaria; Biocrates Absolute IDQp180 kit; CHMO:ultra-performance liquid chromatography-mass spectrometry; MS:flow injection analysis; targeted metabolites 2019-01
MTBLS815 MetaboLights Nutritional quality and genetic differences of five amaranth cultivars revealed by metabolome profiling and whole-genome sequencing (Seed assays) KhalidE Sedeek (postdoc/King Abdullah University of Science and Technology) Amaranthus hypochondriacus::Amaranthus caudatus::Amaranthus cruentus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; NCIT:Nutrition; FOODON:sustainable agriculture food product 2025-02
MTBLS826 MetaboLights Marine metabolomics: measurement of metabolites in seawater by gas chromatography mass spectrometry (Method development) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Artifical sea water CRISP:method development; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; MESH:Seawater 2019-11
MTBLS825 MetaboLights Sphingolipid-dependent Dscam sorting regulates axon segregation Kristaps Klavins (CeMM - Research Center for Molecular Medicine) Drosophila melanogaster MMO:mass spectrometry; Neuronal differentiation; NCIT:Lipidomics; NIFSTD:sphingolipid; EFO:Drosophila melanogaster 2019-03
MTBLS816 MetaboLights Correlation-based Deconvolution (CorrDec) to generate high-quality MS2 spectra from data-independent acquisition in multi-sample studies (Urine assay) Romanas Chaleckis (Nagoya City University) Homo sapiens::blank CHMO:liquid chromatography-mass spectrometry; untargeted metabolites; CHMO:tandem mass spectrometry 2020-07
MTBLS824 MetaboLights MaHPIC Experiment 06: Quantitative Metabolomics from Macaca mulatta infected with Plasmodium knowlesi sporozoites to produce and integrate clinical, hematological, parasitological, omics, telemetric and histopathological measures of acute primary infection Jessica Kissinger (Institute of Bioinformatics, University of Georgia) Homo sapiens::blank::reference compound::Macaca mulatta;NCBITAXON:Plasmodium knowlesi NCIT:Malaria; MTBLS:Biocrates Absolute IDQp180 kit; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:flow injection analysis-mass spectrometry; targeted metabolites; CHMO:tandem mass spectrometry 2019-01
MTBLS822 MetaboLights MaHPIC Experiment 07A and 07B: Quantitative Metabolomics from Macaca fascicularis infected with Plasmodium knowlesi sporozoites to produce and integrate clinical, hematological, parasitological, omics, telemetric and histopathological measures of acute primary infection Jessica Kissinger (Institute of Bioinformatics, University of Georgia) Homo sapiens::blank::reference compound::Macaca fascicularis;NCBITAXON:Plasmodium knowlesi NCIT:Malaria; MTBLS:Biocrates Absolute IDQp180 kit; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:flow injection analysis-mass spectrometry; MTBLS:targeted metabolites; CHMO:tandem mass spectrometry 2019-01
MTBLS832 MetaboLights Metabolic effects of dietary glycerol supplementation in muscle and liver of European seabass and rainbow trout by 1H NMR metabolomics Mariana Palma (Universidade de Coimbra) Oncorhynchus mykiss::Dicentrarchus labrax IOBC:aquaculture; aquafeed; MTBLS:untargeted metabolites; CHEBI:glycerol; IOBC:dietary supplementation; CHMO:nuclear magnetic resonance spectroscopy; diet optimization 2020-02
MTBLS833 MetaboLights Rare and common genetic determinants of metabolic individuality and their effects on human health (EPIC-Norfolk study assays) Adam Butterworth (University of Cambridge) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; EDAM:GWAS study; NCIT:Genetics; EFO:disease; CHMO:tandem mass spectrometry 2022-09
MTBLS834 MetaboLights Rare and common genetic determinants of metabolic individuality and their effects on human health (INTERVAL study assays) Adam Butterworth (University of Cambridge) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; EDAM:GWAS study; NCIT:Genetics; EFO:disease; CHMO:tandem mass spectrometry 2022-09
MTBLS839 MetaboLights Marine metabolomics: measurement of metabolites in seawater by gas chromatography mass spectrometry (The effect of salt and water on metabolite detection) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Artifical sea water::Artifical water sample CRISP:method development; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; MESH:Seawater 2019-11
MTBLS841 MetaboLights Characterization of Yak Common Biofluids Metabolome by Means of Proton Nuclear Magnetic Resonance Spectroscopy Luca Laghi (Bologna University) Bos grunniens untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2019-03
MTBLS836 MetaboLights Antidiabetic and cardiovascular beneficial effects of a liver-localized mitochondrial uncoupler Yuya Hidoh (Otsuka Pharmaceutical Co, Ltd) buffer::Rattus norvegicus GO:oxidative phosphorylation uncoupler activity; EFO:diabetes mellitus; OVAE:cardiovascular AE; EFO:non-alcoholic fatty liver disease; NCIT:Lipidomics; flow injection analysis mass spectrometry; MTBLS:targeted metabolites; MTBLS:Biocrates Absolute IDQp400 kit 2019-05
MTBLS840 MetaboLights Metabolomic and gene expression approaches reveal the developmental and environmental regulation of the secondary metabolism of yacón (Smallanthus sonchifolius, Asteraceae) Guillermo PadillaGonzalez (University of Sao Paulo) Smallanthus sonchifolius untargeted metabolites; ENVO:whole plant development stage; BOF:Environment; CHMO:ultra-performance liquid chromatography-mass spectrometry; AURA:Biogeography; GAZ:Andean Region 2020-03
MTBLS843 MetaboLights Marine metabolomics: measurement of metabolites in seawater by gas chromatography mass spectrometry (Cell culture sampling) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Marinobacter adhaerens CRISP:method development; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; MESH:Seawater 2019-11
MTBLS842 MetaboLights Standardization procedures for real-time breath analysis by secondary electrospray ionization high-resolution mass spectrometry Georgi Tancev (University Children's Hospital) Homo sapiens CHMO:secondary electrospray ionisation mass spectrometry; untargeted metabolites; CHEBI:volatile organic compound; NCIT:Breath Test; CHEBI:fatty aldehyde; NCIT:Oxidative Stress; NCIT:Variability 2020-01
MTBLS844 MetaboLights Marine metabolomics: measurement of metabolites in seawater by gas chromatography mass spectrometry Manuel Liebeke (Max Planck Institute of Marine Microbiology) sea water CRISP:method development; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; MESH:Seawater 2019-11
MTBLS846 MetaboLights A metabolic dependency for host isoprenoids in the obligate intracellular pathogen Rickettsia parkeri underlies a sensitivity for the statin class of host-targeted therapeutics Charles Berdan (UC Berkeley) Chlorocebus sabaeus;NCBITAXON:Rickettsia parkeri::Chlorocebus sabaeus MTBLS:targeted metabolites; MESH:Host-Pathogen Interactions; CHEBI:isoprenoid; CHMO:liquid chromatography-mass spectrometry 2019-10
MTBLS847 MetaboLights Evaluation of sample preparation protocols for quantitative NMR-based metabolomics Olga Snytnikova (International Tomography Center) Homo sapiens CHMO:1H nuclear magnetic resonance spectroscopy; MTBLS:targeted metabolites; NCIT:Method Development; NCIT:Lipidomics; CHMO:quantitative determination method 2024-07
MTBLS849 MetaboLights Marine metabolomics: measurement of metabolites in seawater by gas chromatography mass spectrometry Manuel Liebeke (Max Planck Institute of Marine Microbiology) Artifical sea water CRISP:method development; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; MESH:Seawater 2019-11
MTBLS848 MetaboLights Marine metabolomics: measurement of metabolites in seawater by gas chromatography mass spectrometry (Method quantification) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Artifical sea water CRISP:method development; untargeted metabolites; CHMO:gas chromatography-mass spectrometry; MESH:Seawater 2019-11
MTBLS855 MetaboLights A multi-omic profiles of fruits regarding the maturation of Olive (Olea europaea L.) (GC-MS assay) Guodong Rao (Research Institute of Forestry, Chinese Academy of Forestry) Olea europaea targeted metabolites; CHEBI:fatty acid; CHMO:gas chromatography-mass spectrometry 2019-05
MTBLS856 MetaboLights Serine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity Charandeep Singh (Cole eye institute, Cleveland Clinic) Mus musculus MP:Hyperoxia; CHEBI:roxadustat; CHMO:high performance liquid chromatography-tandem mass spectrometry; HINO:HIF; MTBLS:untargeted metabolites 2019-07
MTBLS852 MetaboLights Sulfadiazine Sodium Improves Dysfunctional Metabolomics in Toxoplasma gondii-infected Mice ChunXue Zhou (Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences) Mus musculus untargeted metabolites; NCIT:Sulfadiazine Sodium; EFO:biomarker; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:Toxoplasma gondii; NCIT:Parasite 2019-06
MTBLS859 MetaboLights Metabolomics revealed the influence of breast cancer on lymphatic endothelial cell metabolism, metabolic crosstalk, and lymphangiogenic signaling in co-culture Suehelay Acevedo (University of Wisconsin-Madison) Homo sapiens MTBLS:untargeted metabolites; DOID:breast cancer; CHEBI:tracer; NCIT:Lactic Acid; CHMO:1H nuclear magnetic resonance spectroscopy; NCIT:Tumor Microenvironment 2024-06
MTBLS851 MetaboLights Untargeted In Silico Compound Classification - A Novel Metabolomics Method to Assess the Chemodiversity in Bryophytes Steffen Neumann (Leibniz Institute of Plant Biochemistry) Calliergonella cuspidata::Barbula unguiculata::Tortula muralis::Polytrichum strictum::Brachythecium rutabulum::Hypnum cupressiforme::Plagiomnium undulatum::Rhytidiadelphus squarrosus::Grimmia pulvinata::Marchantia polymorpha NCIT:Non-Vascular Plant; MTBLS:species diversity; NCIT:Data-Independent Acquisition; SWATH MS; Bryophytes; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Classification 2026-01
MTBLS858 MetaboLights Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells Isabel Vincent (University of Glasgow) Homo sapiens CHEBI:deoxyglucose; CHEBI:Metformin; CHEBI:iobenguane (131I); CHEBI:sensitiser; DOID:cancer; MTBLS:untargeted metabolites; MTBLS:Glasgow Polyomics; CHMO:liquid chromatography-mass spectrometry 2022-11
MTBLS862 MetaboLights Evaluation of Sample Preparation Methods for the Analysis of Reef-Building Corals Using 1H-NMR-based Metabolomics Erik Andersson (National Institute of Standards and Technology) Acropora cervicornis::Porites compressa::Orbicella faveolata CRISP:method development; untargeted metabolites; ENVO:coral reef; CHMO:nuclear magnetic resonance spectroscopy 2019-03
MTBLS861 MetaboLights Environmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice Ming Lei (Tufts University) Mus musculus MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:diethylhexyl phthalate; EFO:microbiome; NCIT:Neurodevelopmental Disorder; CHMO:tandem mass spectrometry 2022-01
MTBLS850 MetaboLights Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study JoannDiray Arce (Boston Childrens Hospital, Harvard Medical School) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; DOID:COVID-19 2024-01
MTBLS863 MetaboLights Metabolic Profiling of CSF from People Suffering from Sporadic and LRRK2 Parkinson's Disease: A Pilot Study Ali Yilmaz (Research Fellow/ William Beaumont Research) Homo sapiens MTBLS:targeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Metabolic Pathway; EFO:Parkinson's disease; NCIT:Machine Learning 2022-09
MTBLS864 MetaboLights Multitrait engineering of Hassawi red rice for sustainable cultivation KhalidE Sedeek (postdoc/King Abdullah University of Science and Technology) Oryza sativa CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; MTBLS:Hassawi rice; BAO:CRISPR/Cas9 method; AGRO:sustainable agriculture process; MTBLS:Trait engineering; NCIT:Whole Genome Sequencing 2023-12
MTBLS868 MetaboLights Mining for natural product antileishmanials in a fungal extract library Clement Regnault (Glasgow Polyomics) Leishmania mexicana::Sample preparation blank DERMO:cutaneous leishmaniasis; EFO:Leishmania mexicana; natural product; screening; fractionation; BRO:Metabolomics; CHMO:Liquid chromatography mass spectrometry; MTBLS:untargeted metabolites; MTBLS:Glasgow Polyomics 2021-02
MTBLS869 MetaboLights An integrated genomic and metabolomic approach for defining survival time in adult oligodendrogliomas patients Caroline Bund (Strasbourg Hospital) Homo sapiens CHMO:magic angle spinning nuclear magnetic resonance spectroscopy; NCIT:Survival; NCIT:IDH Gene Family; untargeted metabolites; GEXO:PTEN 2021-10
MTBLS867 MetaboLights Untargeted metabolomics reveals alterations in metabolites of lipid metabolism and immune pathways in serum of rats after long term oral administration of Amalaki rasayana Aneesh Kumar (RGCB) Rattus norvegicus MESH:Amalakirasayana; EFO:inflammation; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2019-05
MTBLS870 MetaboLights Effect of glycerol feed-supplementation on seabass metabolism and gut microbiota Mariana Palma (Universidade de Coimbra) Dicentrarchus labrax IOBC:aquaculture; aquafeed; MTBLS:untargeted metabolites; CHEBI:glycerol; IOBC:dietary supplementation; CHMO:nuclear magnetic resonance spectroscopy; diet optimization 2020-07
MTBLS871 MetaboLights A metabolomics-based approach for the evaluation of off-tree ripening conditions and different postharvest treatments in mangosteen (Garcinia mangostana) (Peel parts assay) AnjarithaAuliaRizky Parijadi (Osaka University) Garcinia mangostana MTBLS:untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:fruit ripening; NCIT:Fruit 2021-02
MTBLS866 MetaboLights Untargeted Metabolite Profiling (GC-MS) of Root Exudates of Grassland Species Steffen Neumann (Leibniz Institute of Plant Biochemistry) Blank sample::Arrhenatherum elatius::Alopecurus pratensis::G.mollugo::Achillea millefolium::Galium verum::quality control::Poa pratensis::Galium mollugo::Plantago lanceolata::Dactylis glomerata::Ranunculus acris::Lolium perenne MMO:gas chromatography-mass spectrometry; SWO:Metabolomics; untargeted profiling; ENVO:grassland; ENVO:climate; ENVO:soil; plant functional traits 2020-06
MTBLS872 MetaboLights A metabolomics-based approach for the evaluation of off-tree ripening conditions and different postharvest treatments in mangosteen (Garcinia mangostana) (Flesh parts assay) AnjarithaAuliaRizky Parijadi (Osaka University) Garcinia mangostana MTBLS:untargeted metabolites; CHMO:gas chromatography-mass spectrometry; GO:fruit ripening; NCIT:Fruit 2021-02
MTBLS865 MetaboLights Untargeted Metabolite Profiling (LC-MS) of Root Exudates of Grassland Species Steffen Neumann (Leibniz Institute of Plant Biochemistry) Blank sample::Quality control::Arrhenatherum elatius::Alopecurus pratensis::Achillea millefolium::Galium verum::Poa pratensis::Reference compound mix::Galium mollugo::Plantago lanceolata::Dactylis glomerata::Ranunculus acris::Lolium perenne Metabolomics; ENVO:grassland; BOF:Vegetation; plant functional traits; Environment; ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites 2020-06
MTBLS873 MetaboLights Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells Rodrigo LopezMunoz (Universidad Austral de Chile) Homo sapiens EFO:non-small cell lung carcinoma; CHEBI:indomethacin; MTBLS:spermidine/spermine-N1-acetyltransferase; CHMO:gas chromatography-mass spectrometry; MTBLS:untargeted metabolites; CHEBI:polyamine 2021-02
MTBLS876 MetaboLights Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders Yi Yang (Imperial College London) Homo sapiens SNOMEDCT:Small bowel bacterial overgrowth syndrome; SNOMEDCT:Functional disorder of gastrointestinal tract; CHMO:nuclear magnetic resonance spectroscopy; NCIT:Aspirate; untatgeted metabolites; NCIT:Low Fat, High Fiber Diet; RCD:Low fibre diet 2019-04
MTBLS882 MetaboLights Novel Minor Groove Binders cure animal African trypanosomiasis in an in vivo mouse model Federica Giordani (University of Glasgow) blank::Trypanosoma brucei NCIT:DNA Minor Groove Binding; MTBLS:Strathclyde-minor groove binders; EFO:drug resistance; NCIT:Mode of Action; NCIT:Antiprotozoal Agent; CHMO:tandem mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:Glasgow Polyomics 2022-01
MTBLS874 MetaboLights Marine Biodiscovery Ireland 2017 Samples Olivier Thomas (University of Galway) Haliclona cinerea::Dysidea fragilis::Suberites ficus::Eupolymnia nebulosa::Hymeniacidon perlevis::Stylostichon plumosum::Halichondria panicea::Corella eumyota::Haliclona fistulosa::Alcyonium digitatum::Morchellium argus::Amphilectus fucorum::Archidoris pseudoargus::Ophlitaspongia papilla::Psammechinus miliaris::Aplidium pallidum::Stelligera rigida::Halidrys siliquosa::Aslia lefevrei::Spongosorites calcicola::Tethya citrina::Ciona intestinalis::Paracentrotus lividus::Cliona celata::Leucosolenia botryoides::Alentia gelatinosa::Mycale contarenii::Grantia compressa::Dendrodoa grossularia marine; Ireland; Ultra-Performance Liquid Chromatography-Mass Spectrometry; nuclear magnetic resonance spectroscopy; untargeted metabolites; NCIT:Marine-based natural product 2020-02
MTBLS889 MetaboLights Transcriptome and metabolite profiling reveals that prolonged drought modulates the phenylpropanoid and terpenoid pathway in white grapes (Vitis vinifera L.) (Carotenoids; UPLC-DAD assay) Stefania Savoi (fondazione mach) Vitis vinifera IOBC:water deficit; IOBC:abiotic stress; PLOSTHES:Grapevine; MTBLS:Fruit Ripening; MTBLS:Carotenoids; CHMO:liquid chromatography-photodiode array detection; FOODON:white grape (whole) 2021-08
MTBLS890 MetaboLights An ancient residue metabolomics-based method to distinguish use of closely related plant species in ancient pipes Korey Brownstein (Washington State University) Nicotiana rustica::Rhus glabra::Nicotiana attenuata::Pre-Contact Pipe::Nicotiana quadrivalvis::Taxus brevifolia::Cornus sericea::Arctostaphylos uva-ursi::experimental blank::reference compound::Nicotiana tabacum MTBLS:Ancient residue metabolomics; MTBLS:Archaeology; MTBLS:Caffeine; CHEBI:Nicotine; MTBLS:Pre-contact pipe; MTBLS:Psychoactive Compound; MTBLS:Smooth Sumac; MTBLS:Tobacco 2020-07
MTBLS883 MetaboLights Changing environments and genetic variation: natural variation in inbreeding does not compromise short-term physiological responses Ronan Daly (University of Glasgow) Arabidopsis lyrata untargeted metabolites; MESH:Inbreeding; NCIT:Mating; MESH:Self-Fertilization; EFO:genetic variation; CHMO:high-performance liquid chromatography-mass spectrometry; NCIT:Physiology; MESH:Cell Plasticity; MTBLS:Glasgow Polyomics 2019-10
MTBLS892 MetaboLights Transcriptome and metabolite profiling reveals that prolonged drought modulates the phenylpropanoid and terpenoid pathway in white grapes (Vitis vinifera L.) (Volatile organic compounds; SPME-GC-MS assay) Stefania Savoi (fondazione mach) Vitis vinifera IOBC:water deficit; untargeted metabolites; IOBC:abiotic stress; PLOSTHES:Grapevine; FOODON:white grape (whole); CHEBI:volatile organic compound; CHMO:headspace solid-phase micro-extraction; CHMO:gas chromatography-mass spectrometry 2021-08
MTBLS881 MetaboLights Metabotyping Patients' Journeys Reveals Early Predisposition to Lung Injury after Cardiac Surgery Raluca Maltesen (Westmead Institute for Medical Research) Homo sapiens MESH:Interrupted Time Series Analysis; ONTODM-CORE:dataset sampling; CHMO:Nuclear magnetic resonance spectroscopy; MTBLS:untargeted metabolites; EFO:Cardiovascular disease; MTBLS:lung injury 2020-05
MTBLS884 MetaboLights Evaluation of extraction solvents for untargeted metabolomics analysis of enrichment reactor cultures performing enhanced biological phosphorus removal (EBPR) NayMinMinThaw Saw (Singapore Center for Environmental Life Science Engineering) blank::microbial community untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; polyphosphate accumulating organisms; EDAM:Microbial ecology; ENVO:activated sludge; enhanced biological phosphate removal 2019-08
MTBLS893 MetaboLights Metabolic alterations in pea leaves during arbuscular mycorrhiza development Roman Puzanskiy (St. Petersburg Universisity) Pisum sativum MTBLS:untargeted metabolites; CHMO:gas chromatography-mass spectrometry; IOBC:Arbuscular mycorrhiza; IOBC:plant growth; PATO:physiological state 2020-02
MTBLS891 MetaboLights Harnessing microbial-derived metabolites in the urinary tract to prevent infection induced catheter encrustation Chelsie Armbruster (University at Buffalo) Enterococcus faecalis::Morganella morganii::Klebsiella aerogenes::Staphylococcus aureus::Providencia stuartii::blank::Proteus mirabilis CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; OOSTT:catheter related urinary tract infection; NCIT:In Vitro Model; NCIT:Bladder 2025-08
MTBLS897 MetaboLights Transcriptome and metabolite profiling reveals that prolonged drought modulates the phenylpropanoid and terpenoid pathway in white grapes (Vitis vinifera L.) (Phenolics; UPLC-MS/MS assay) Stefania Savoi (fondazione mach) Vitis vinifera IOBC:water deficit; untargeted metabolites; IOBC:abiotic stress; CHEBI:polyphenol; PLOSTHES:Grapevine; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; FOODON:white grape (whole) 2019-04
MTBLS898 MetaboLights Multi-Omics and Integrated Network Analyses Reveal New Insights into the Systems Relationships between Metabolites, Structural Genes, and Transcriptional Regulators in Developing Grape Berries (Vitis vinifera L.) Exposed to Water Deficit (Phenolics; UPLC-MS/MS assay) Stefania Savoi (fondazione mach) Vitis vinifera IOBC:water deficit; IOBC:abiotic stress; MTBLS:untargeted metabolites; CHEBI:polyphenol; PLOSTHES:Grapevine; GO:fruit ripening; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; FOODON:red grape (whole) 2019-04
MTBLS916 MetaboLights Fecal Metabolomics and Potential Biomarkers for Systemic Lupus Erythematosus Qiong Zhang (Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangdong, P.R. China) Homo sapiens MTBLS:untargeted metabolites; EFO:biomarker; EFO:Systemic lupus erythematosus; CHMO:Ultra-performance liquid chromatography-mass spectrometry; CHMO:Tandem mass spectrometry 2020-01
MTBLS899 MetaboLights A profile of the joint Toxoplasma-host infection metabolome finds broad changes to metabolism and discovers a novel parasite metabolic capability William Olson (University of Wisconsin Madison) Homo sapiens untargeted metabolites; EFO:Toxoplasma gondii; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:transcriptomic data; CHEBI:sedoheptulose 1,7-bisphosphate; CHEBI:sedoheptulose 7-phosphate; BIOMODELS:sedoheptulose-bisphosphatase activity; BIOMODELS:pentose-phosphate shunt, non-oxidative branch; BIOMODELS:pentose-phosphate shunt, oxidative branch 2019-05
MTBLS914 MetaboLights Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males ZHENQI ZHOU (UCLA) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; CHEBI:estrogen; MTBLS:insulin sensitivity; MTBLS:mitochondrial function; PW:mitochondrial DNA replication pathway; GO:mitochondrial crista; GO:cellular respiration; MTBLS:exercise adaptation 2025-04
MTBLS943 MetaboLights Metabolomic evidence for biogeographic segregation in Espeletiinae (Asteraceae): A new perspective on an Andean adaptive radiation in sky islands (Intraspecific chemical variability assay) Guillermo PadillaGonzalez (University of Sao Paulo) Espeletia argentea::Espeletia grandiflora::Espeletia boyacensis untargeted metabolites; AURA:Biogeography; BOF:Environment; GAZ:Andean Region; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-03
MTBLS906 MetaboLights Monitoring of system conditioning after blank injections in untargeted UPLC-MS metabolomic analysis Guillermo Quintas (LEITAT Technological Center) Homo sapiens::blank MTBLS:untargeted metabolites; NCIT:Conditioning; MTBLS:Instrument performance; OBI:longitudinal data analysis; CHMO:ultra-performance liquid chromatography-mass spectrometry 2022-01
MTBLS923 MetaboLights Functional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling floriant Bellvert (Metabohub-MetaToul) reference compound::Saccharomyces cerevisiae EDAM:Fluxomics; MTBLS:absolute quantification; CHMO:isotope dilution mass spectrometry; MTBLS:targeted metabolites; PW:Isoprenoid biosynthetic pathway; CHMO:Ultra-performance liquid chromatography-mass spectrometry 2021-04
MTBLS946 MetaboLights Urinary metabolomics reveals kynurenine pathway perturbation in newborns with transposition of great arteries after surgical repair Manuela Simonato (Fondazione Istituto di Ricerca Pediatrica "Città della Speranza") Homo sapiens::Solvent Blank MTBLS:untargeted metabolites; CHMO:Ultra-performance liquid chromatography-mass spectrometry; EFO:Congenital heart disease; NCIT:Newborn; PW:Kynurenine metabolic pathway; MONDO:Transposition of the great arteries 2020-04
MTBLS944 MetaboLights Metabolomic evidence for biogeographic segregation in Espeletiinae (Asteraceae): A new perspective on an Andean adaptive radiation in sky islands (Interspecific chemical variability assay) Guillermo PadillaGonzalez (University of Sao Paulo) Espeletia dugandii::Espeletia killipii::Espeletiopsis rabanalensis::Espeletia brassicoidea::Espeletia aristeguietana::Espeletia frontinoensis::Espeletia praefrontina::Espeletiopsis corymbosa::Espeletia boyacensis::Espeletia tunjana::Espeletia argentea::Espeletia nemekenei::Espeletia oswaldiana::Ruilopezia::Espeletia azucarina::Espeletia lopezii::Espeletiopsis pleiochasia::Espeletia cuniculorum::Espeletia uribei::Espeletia summapacis::Espeletia discoidea::Espeletia paipana::Espeletia rositae::Espeletia jajoensis::Espeletia ulotricha::Espeletia schultesiana::Espeletia nana::Libanothamnus neriifolius::Espeletia barclayana::Espeletia estanislana::Espeletia jaramilloi::Espeletia brachyaxiantha::Paramiflos glandulosus::Espeletia pisbana::Espeletia annemariana::Espeletia congestiflora::Espeletia formosa::Espeletia roberti::Espeletia arbelaezii::Espeletia conglomerata::Espeletia episcopalis::Espeletia occidentalis::Espeletia pescana::Espeletia semiglobulata::Espeletia weddellii::Espeletia curialensis::Espeletia::Espeletia grandiflora::Espeletia schultzii::Espeletia cleefii::Espeletia murilloi::Libanothamnus::Espeletia ariana::Espeletia incana::Espeletiopsis garciae::Espeletia cayetana untargeted metabolites; BOF:Environment; AURA:Biogeography; GAZ:Andean Region; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-03
MTBLS896 MetaboLights Mapping human microbiome drug metabolism by gut bacteria and their genes Michael Zimmermann (Yale University) Blautia Luti::Bacteroides Uniformis::Hungatella Hathewayi::[Bacteroides] Pectinophilus::Collinsella Aerofaciens::Enterococcus Faecalis::Bryantia formatexigens::Control pH 5::Roseburia Intestinalis::Eggerthella Lenta::Clostridium Bolteae::[Eubacterium] Hallii::Bacteroides Coprophilus::Bacteroides Xylanisolvens::Salmonella Typhimurium::Proteus Penneri::Clostridium Ramosum::Bacteroides Ovatus::Bacteroides Fragilis::Clostridium Spiroforme::Akkermansia Muciniphila::Collinsella Intestinalis::[Ruminococcus] Torques::[Clostridium] Asparagiforme::Bacteroides Caccae::Anaerotruncus Colihominis::Subdoligranulum Variabile::Eubacterium Ventriosum::Prevotella Copri::Ruminococcus Gnavus::Edwardsiella Tarda::Coprococcus Comes::Alistipes Indistinctus::[Clostridium] Scindens::Ruminococcus Lactaris::Escherichia Coli::Parabacteroides Distasonis::Odoribacter Splanchnicus::Bacteroides Intestinalis::Bifidobacterium Ruminantium::Bifidobacterium Breve::Parabacteroides Merdae::Marvinbryantia Formatexigens::Holdemanella Biformis::Parabacteroides Johnsonii::Control pH 6::Bacteroides Vulgatus::Bacteroides Eggerthii::Providencia Alcalifaciens::Bifidobacterium Longum Subsp. Infantis::S039::Erysipelatoclostridium Ramosum::S015::Clostridium Symbiosum::S018::Clostridium Sporogenes::Blautia Hansenii::Bifidobacterium Adolescentis::Dorea Formicigenerans::Control pH 7::Providencia Stuartii::Bacteroides Cellulosilyticus::Victivallis Vadensis::Eubacterium Rectale::Clostridium Difficile::Lactobacillus Reuteri::Control pH 4::Anaerococcus Hydrogenalis::Bacteroides Finegoldii::Anaerostipes Sp.::S027::Providencia Rettgeri::Bacteroides Stercoris::Bacteroides Dorei::Clostridium Sp.::Bacteroides Thetaiotaomicron::Bacteroides Sp. WH2::Enterobacter Cancerogenus CHEBI:Pharmaceutical; IDO:Commensal; OHMI:Human Gut Microbiome; NCIT:Drug metabolism; CHMO:Liquid Chromatography Mass Spectrometry; MTBLS:untargeted metabolites 2019-07
MTBLS951 MetaboLights IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function Slavica TudzarovaTrajkovska (University of California Los Angeles) Rattus norvegicus::blank MTBLS:untargeted metabolites; NCIT:Islet amyloid polypeptide; EFO:Type ii diabetes mellitus; CHMO:Liquid chromatography-mass spectrometry 2020-04
MTBLS952 MetaboLights Effects of Platycodins Folium on Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics Jinping Liu (school of pharmaceutical sciences, Jilin University) Mus musculus MTBLS:untargeted metabolites; EFO:Depression; CHMO:ultra-performance liquid chromatography-mass spectrometry; DRON:Platycodon grandiflorum leaf extract; DOID:major depressive disorder 2020-06
MTBLS954 MetaboLights Determination of Abundant Metabolite Matrix Adducts Illuminates the Dark Metabolome of MALDI-Mass Spectrometry Imaging Datasets Manuel Liebeke (Max Planck Institute of Marine Microbiology) Bathymodiolus Puteoserpentis::Rattus norvegicus::reference compound::Theobroma Cacao::Bathymodiolus Azoricus::Posidonia Oceanica::Mus Musculus::Bathymodiolus Childressi CHMO:Matrix-Assisted Laser Desorption-Ionisation Imaging Mass Spectrometry; NCIT:Matrix; MS:adduct ion; MTBLS:untargeted metabolites; NCIT:Annotation; CHMO:tandem mass spectrometry; MTBLS:Dark metabolome 2021-06
MTBLS959 MetaboLights Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages Mariana SilvadosSantos (The Francis Crick Institute) Homo sapiens::Reference Compound::experimental blank NCBITAXON:Mycobacterium Tuberculosis; MTBLS:untargeted metabolites; NCIT:Lipidomics; NCIT:Tuberculosis; CHMO:liquid chromatography-mass spectrometry; CHMO:microscopy; CHEBI:bedaquiline 2020-12
MTBLS957 MetaboLights Monitoring recombinant protein expression in bacteria by rapid evaporative ionisation mass spectrometry Joscelyn Sarsby (University of Liverpool) Escherichia coli MTBLS:untargeted metabolites; MTBLS:Rapid Evaporative Ionisation Mass Spectrometry; MTBLS:bacteria harvesting plasmid 2022-01
MTBLS962 MetaboLights Flavonoid Biosynthesis Is Likely More Susceptible to Elevation and Tree Age Than Other Branch Pathways Involved in Phenylpropanoid Biosynthesis in Ginkgo Leaves Kai Zou (Central South University) Ginkgo Biloba MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:flavonoid; CHEBI:polyphenol; OMIT:Medicine, Chinese Traditional 2020-12
MTBLS963 MetaboLights The Sphingolipidome of the model organism Caenorhabditis elegans Michael Witting (Helmholtz Zentrum München) Caenorhabditis elegans NCIT:Lipidomics; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2024-04
MTBLS948 MetaboLights Assessment of plasma metabolomic biomarkers in various pediatric diseases Carles HernandezFerrer (Boston Children's Hospital) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Biomarker; IOBC:metabolon; CHMO:tandem mass spectrometry; NCIT:Pediatrics 2024-05
MTBLS968 MetaboLights The accumulation profiles of terpene metabolites in three Muscat table grape cultivars through HS-SPME-GCMS LEI SUN (Beijing Academy of Forestry and Pomology Sciences) Vitis vinifera CHEBI:Terpene; CHMO:gas chromatography-mass spectrometry; untargeted metabolites; CHMO:headspace solid-phase micro-extraction; CHEBI:fragrance; CHEBI:volatile organic compound 2019-11
MTBLS981 MetaboLights Deciphering the metabolic perturbation in hepatic alveolar echinococcosis: a 1H NMR-based metabolomics study Jiyang Dong (Xiamen University) Homo sapiens DOID:alveolar echinococcosis; CHMO:nuclear magnetic resonance spectroscopy; MTBLS:untargeted metabolites; NCIT:Liver; CHEBI:biomarker 2021-08
MTBLS984 MetaboLights Multi-Omics and Integrated Network Analyses Reveal New Insights into the Systems Relationships between Metabolites, Structural Genes, and Transcriptional Regulators in Developing Grape Berries (Vitis vinifera L.) Exposed to Water Deficit (Carotenoids; UPLC-DAD assay) Stefania Savoi (fondazione mach) Vitis vinifera IOBC:water deficit; IOBC:abiotic stress; PLOSTHES:Grapevine; GO:fruit ripening; NCIT:Carotenoid; CHMO:liquid chromatography-photodiode array detection; FOODON:red grape (whole) 2021-08
MTBLS982 MetaboLights Multi-Omics and Integrated Network Analyses Reveal New Insights into the Systems Relationships between Metabolites, Structural Genes, and Transcriptional Regulators in Developing Grape Berries (Vitis vinifera L.) Exposed to Water Deficit (Volatile organic compounds; SPME-GC-MS assay) Stefania Savoi (fondazione mach) Vitis vinifera IOBC:water deficit; IOBC:abiotic stress; MTBLS:untargeted metabolites; CHEBI:polyphenol; PLOSTHES:Grapevine; GO:fruit ripening; CHMO:gas chromatography-mass spectrometry; FOODON:red grape (whole); CHEBI:volatile organic compound; CHMO:headspace solid-phase micro-extraction 2021-08
MTBLS975 MetaboLights Elevated brain manganese induces motor disease by upregulating the kynurenine pathway of tryptophan metabolism Somshuvra Mukhopadhyay (The University of Texas at Austin) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; CHEBI:manganese molecular entity; EFO:motor neuron disease; GO:kynurenine metabolic process; NCIT:Tryptophan Metabolism Pathway 2025-03
MTBLS1014 MetaboLights 1H HR-MAS NMR based metabolomics of cancer cells responding to two different doses of the diruthenium trithiolato complex [(p-MeC6H4iPr)2Ru2(SC6H4-p-But)3]+ (DiRu-1) Hedvika Primasov (University of Bern, Department of Chemistry and Biochemistry) Homo sapiens EFO:ovarian cancer; SNOMEDCT:Ruthenium and ruthenium compound; untargeted metabolites; NCIT:Cell Line; CHMO:magic angle spinning nuclear magnetic resonance spectroscopy 2019-07
MTBLS1024 MetaboLights Organic sulfur: a spatially variable, labile, and understudied component of marine organic matter Krista Longnecker (Woods Hole Oceanographic Institution) sea water untargeted metabolites; Direct Infusion Mass Spectrometry; CHEBI:sulfur molecular entity; GAZ:North Atlantic Ocean 2019-11
MTBLS980 MetaboLights Gut-derived metabolites drive Th17 cell pathogenicity in multiple sclerosis Jessica Rebeaud (University of Lausanne) Homo sapiens::Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; DOID:multiple sclerosis; EFO:neuroinflammatory disorder; EFO:experimental autoimmune encephalomyelitis; mesh:Brain-Gut Axis; EFO:microbiome; CHEBI:indoles 2025-08
MTBLS1015 MetaboLights Metabolic alterations in immune cells associate with progression to type 1 diabetes Partho Sen (Turku Center for Biotechnology, University of Turku) Homo sapiens MTBLS:Lipidomics; NCIT:Metabolomics; operation:Metabolic Network Modelling; MTBLS:targeted metabolites; MTBLS:untargeted metabolites; MTBLS:ultra-performance liquid chromatography-mass spectrometry; MTBLS:blood metabolome; MTBLS:gas chromatography time-of-flight mass spectrometry; EFO:autoimmune type 1 diabetes 2020-08
MTBLS999 MetaboLights A database of high-resolution MS/MS spectra for lichen metabolites Damien Olivier (ISCR, CORINT) reference compound NCIT:Database; CHMO:liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Natural Product; MS:ms-ms search 2019-07
MTBLS974 MetaboLights The Leiden Longevity Study: Identification of biomarkers of the rate of ageing Aswin Verhoeven (Center for Proteomics and Metabolomics, Leiden University Medical Center) Homo sapiens EFO:longevity; EFO:biomarker; CHMO:nuclear magnetic resonance spectroscopy; MTBLS:untargeted metabolites 2019-07
MTBLS1039 MetaboLights A Pathogen-Responsive Gene Cluster for Highly Modified Fatty Acids in Tomato Curt Fischer (Stanford University) Solanum lycopersicum MTBLS:untargeted metabolites; EFO:pathogen; NCIT:Genomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:fatty acid; CHEBI:falcarindiol 2022-01
MTBLS1033 MetaboLights Metabolomics Study of Serum and Urine Samples Reveals Metabolic Pathways and Biomarkers Associated with Pelvic Organ Prolapse Jun Rao (Jiangxi Cancer Center) Homo sapiens untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:pelvic organ prolapse; EFO:biomarker 2019-08
MTBLS1045 MetaboLights Metabolome and proteome changes in skeletal muscle and blood of pre-weaning calves fed leucine and threonine supplemented diets Kuai Yu (Universitat Autonoma de Barcelona) Bos taurus OCHV:amino acid supplementation; EOL:livestock feeding; ATC:Milk substitutes; NCIT:Dietary Supplement; untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; SNOMEDCT:Weaning diet 2020-02
MTBLS1041 MetaboLights Metabolic Phenotypes of Hypoxic-Ischemic Encephalopathy with Normal vs. Pathologic Magnetic Resonance Imaging Outcomes Julia Kuligowski (Health Research Institute La Fe) Blank::Homo sapiens MONDO:perinatal asphyxia; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Neonatal Hypoxic Ischemic Encephalopathy; NCIT:Magnetic Resonance Imaging; CHMO:tandem mass spectrometry 2021-11
MTBLS1044 MetaboLights Systematic identification of metabolites controlling gene expression in E. coli Hannes Link (Max Planck Institute for terrestrial Microbiology) Escherichia coli CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; NCIT:Gene Expression; NCIT:Transcription Factor 2019-08
MTBLS1051 MetaboLights Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes Klev Diamanti (Department of Immunology, Genetics and Pathology, Uppsala University, Sweden) Homo sapiens MTBLS:diabetes mellitus; MTBLS:untargeted metabolites; NCIT:Insulin Sensitivity Measurement; NCIT:Positron Emission Tomography And Magnetic Resonance Imaging; OBI:Machine Learning; NCIT:Classification 2020-01
MTBLS1066 MetaboLights Untargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models David Licha (University of Salzburg, Department of Biosciences, Bioanalytical Research Lab) Mus Musculus::Mus musculus::blank EFO:Ketogenic Diet; EFO:breast cancer; EFO:Xenograft; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2019-10
MTBLS1071 MetaboLights Metabolomic fingerprinting of bull spermatozoa for identification of fertility signature metabolites Arumugam Kumaresan (Principal Scientist, ICAR-National Dairy Research Institute, Karnal) Bos taurus CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Fertility; OMIT:Spermatozoa; MTBLS:cross-breading; MTBLS:untargeted metabolites 2021-12
MTBLS1073 MetaboLights Human Cytomegalovirus pUL37x1 is Important to Remodeling of Host Lipid Metabolism John Purdy (University of Arizona) Homo sapiens untargeted metabolites; NCIT:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry 2020-06
MTBLS1040 MetaboLights Creating a Reliable Mass Spectral–Retention Time Library for All Ion Fragmentation-Based Metabolomics Romanas Chaleckis (Nagoya City University) reference compound CHMO:liquid chromatography-mass spectrometry; ERO:chemical library; All-ion fragmentation; mass spectral deconvolution; CHMO:tandem mass spectrometry 2019-10
MTBLS1080 MetaboLights The genome analysis of Tripterygium wilfordii reveals TwCYP712K1 and TwCYP712K2 responsible for oxidation of friedelin in celastrol biosynthesis pathway Tianlin Pei (Shanghai Chenshan Botanical Garden) Tripterygium wilfordii::Reference compound::Saccharomyces cerevisiae CHMO:Liquid chromatography mass spectrometry; CHEBI:celastrol; NCIT:Cytochrome P450; MTBLS:targeted metabolites; NCIT:Chinese Herbs 2021-02
MTBLS1093 MetaboLights Impact of Diabetic Stress Conditions on Renal Cell Metabolome Simon Lagies (Center for biological systems analysis, University of Freiburg) Homo sapiens::Mus musculus CHMO:gas chromatography-mass spectrometry; LOINC:Diabetic Kidney Disease; untargeted metabolites; EFO:immortal cell line cell 2019-10
MTBLS1103 MetaboLights Limitations to Starch Utilization in Barramundi (Lates calcarifer) as Revealed by NMR-Based Metabolomics Mariana Palma (Universidade de Coimbra) Lates calcarifer IOBC:aquaculture; aquafeed; untargeted metabolites; IOBC:dietary supplementation; CHMO:nuclear magnetic resonance spectroscopy; diet optimization; MTBLS:hepatic glycogen 2020-07
MTBLS1079 MetaboLights Metabolic Profiling of Escherichia coli-Based Cell-Free Expression Systems for Process Optimization April Miguez (Georgia Institute of Technology) Escherichia coli::blank MTBLS:untargeted metabolites; MTBLS:two-dimensional gas chromatography mass spectrometry; NCIT:Cell-free System; REX:addition reaction; MTBLS:Imaging probe 2020-06
MTBLS1085 MetaboLights Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation AnaSofia HenriquesdaCosta (Cold Spring Harbor Laboratory) Sus Scrofa::Mus Musculus::Homo sapiens untargeted metabolites; EFO:ischemia reperfusion injury; NCIT:Heart transplantation; MESH:Organ Preservation; CHMO:high-performance liquid chromatography-mass spectrometry 2019-09
MTBLS1104 MetaboLights Comparison of singlequad and Orbitrap mass analyzer coupled to gas chromatography reveals potential of high resolution GC MS for untargeted metabolomics Daniel Stettin (Friedrich-Schiller-University Jena/ Pohnert lab) Skeletonema costatum GO:cellular response to salt stress; CHMO:gas chromatography-mass spectrometry; CHMO:high-resolution mass spectrometry; SNOMEDCT:Diatom; GO:cellular hyperosmotic salinity response; untargeted metabolites 2020-01
MTBLS1106 MetaboLights Transcriptomic and metabolomic changes in postharvest sugarbeet roots reveal widespread metabolic changes in storage and identify genes potentially responsible for respiratory sucrose loss Sidney James (EMBL-EBI) Beta vulgaris CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; CHEBI:sucrose; AGRO:agricultural product storage process; AGRO:harvested crop; MTBLS:bidirectional sugar transporter SWEET gene; NCIT:Glycolysis; CHEBI:biomarker; NCIT:Pyruvate Kinase; NCIT:Respiration 2024-05
MTBLS1095 MetaboLights Rapid identification of species, sex and maturity by mass spectrometric analysis of animal faeces Natalie Koch (University of Liverpool ) Microtus agrestis::Rattus norvegicus::Myodes glareolus::Mus musculus::Apodemus sylvaticus::Mus musculus domesticus Faecal analysis; MTBLS:Rapid Evaporative Ionisation Mass Spectrometry; Species Identification; NCBITAXON:Rodentia; MTBLS:untargeted metabolites 2022-02
MTBLS1107 MetaboLights Longitudinal Deep Multi-Omics Profiling in a<i>CLN3<sup>Δex7/8</sup></i>Minipig Model Reveals Novel Biomarker Signatures for Batten Disease Jon Brudvig (Sanford Research) Sus scrofa CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; MONDO:neuronal ceroid lipofuscinosis 3; CHEBI:biomarker; NCIT:Lipidomics 2025-08
MTBLS1108 MetaboLights DIAMetAlyzer allows automated false-discovery rate-controlled analysis for data-independent acquisition in metabolomics Oliver Alka (Applied Bioinformatics / University of Tübingen) Homo sapiens::reference compound::experimental blank PRIDE:SWATH MS; MTBLS:targeted metabolites; NCIT:False Discovery Rate; MTBLS:metabolite library; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2022-09
MTBLS1115 MetaboLights In Vitro and In Vivo Metabolomic Profiling after Infection with Virulent Newcastle Disease Virus panrao liu (Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences) Gallus Gallus MTBLS:untargeted metabolites; MTBLS:ultra-performance liquid chromatography-mass spectrometry; NCBITAXON:Newcastle disease virus 2019-12
MTBLS1127 MetaboLights A multi-omic profiles of fruits regarding the maturation of Olive (Olea europaea L.) (Tyrosol only UPLC-MS assay) Guodong Rao (Research Institute of Forestry, Chinese Academy of Forestry) Olea europaea targeted metabolites; CHEBI:flavonoid; CHMO:ultra-performance liquid chromatography-mass spectrometry 2019-07
MTBLS1122 MetaboLights Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype (UPLC-MS HILIC POS assay) Yuping Cai (Yale University) Homo sapiens MTBLS:untargeted metabolites; HP:Colon cancer; MTBLS:Sex-Differences; CHMO:tandem mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry 2020-03
MTBLS1124 MetaboLights Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype (UPLC-MS HILIC NEG assay) Yuping Cai (Yale University) Homo sapiens HP:Colon cancer; MTBLS:untargeted metabolites; MTBLS:Sex-Differences; CHMO:tandem mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry 2020-03
MTBLS1129 MetaboLights Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype (UPLC-MS RP POS assay) Yuping Cai (Yale University) Homo sapiens HP:Colon cancer; MTBLS:Sex-Differences; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-03
MTBLS1130 MetaboLights Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype (UPLC-MS RP NEG assay) Yuping Cai (Yale University) Homo sapiens MTBLS:untargeted metabolites; HP:Colon cancer; MTBLS:Sex-Differences; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-03
MTBLS1140 MetaboLights 4-octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects Shanting Liao (China Pharmaceutical University) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:inflammatory disease; untargeted metabolites; 4-octyl itaconate; OMIM:GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE 2019-10
MTBLS1132 MetaboLights Gastropods and Insects Prefer Different Solanum dulcamara Chemotypes OnnoW Calf (Radboud University) Solanum dulcamara EFO:metabolomic profiling; CHMO:quadrupole time-of-flight mass spectrometer; CHMO:ultra high performance liquid chromatography; BOF:Plant; chemical diversity; BIOMODELS:response to herbivore 2020-05
MTBLS1133 MetaboLights Troubleshooting in Large-Scale LC-ToF-MS Metabolomics Analysis: Solving Complex Issues in Big Cohorts Juan RodriguezCoira (Universidad CEU San Pablo) blank::Homo sapiens EFO:asthma; untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry 2019-12
MTBLS1138 MetaboLights Fatty acid transport protein 4 is required for incorporation of saturated ultralong-chain fatty acids into epidermal ceramides and monoacylglycerols MeeiHua Lin (Washington University in St. Louis) Mus musculus MTBLS:Direct Infusion Mass Spectrometry; NCIT:Lipidomics; EFO:skin disease; CHEBI:fatty acid; CHEBI:sphingolipid 2021-07
MTBLS1145 MetaboLights Towards a semi-automated metabolic profile analysis of fish blood plasma by 1H NMR Mariana Palma (Universidade de Coimbra) Dicentrarchus labrax IOBC:aquaculture; aquafeed; MTBLS:untargeted metabolites; CHEBI:glycerol; IOBC:dietary supplementation; CHMO:nuclear magnetic resonance spectroscopy; diet optimization 2022-02
MTBLS1167 MetaboLights Untargeted metabolomics to understand the basis of phenotypic differences in amphotericin B-resistant Leishmania parasites Andrew Pountain (University of Glasgow) blank::Leishmania mexicana CHEBI:amphotericin B; CHMO:liquid chromatography-mass spectrometry; untargeted metabolites; MESH:Drug Resistance 2019-09
MTBLS1182 MetaboLights Absence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in Aeromonas veronii Yu Wenjing (Hainan University) Aeromonas veronii MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; SO:tmRNA; CHEBI:cefotaxime; CHEBI:peptidoglycan; CHMO:tandem mass spectrometry 2021-10
MTBLS1186 MetaboLights The impact of persistent colonization by Vibrio fischeri on the metabolome of the host squid Euprymna scolopes Manuel Liebeke (Max Planck Institute of Marine Microbiology) Euprymna scolopes MTBLS:untargeted metabolites; EFO:Circadian rhythm; NCBITAXON:Aliivibrio fischeri; CHMO:Gas chromatography-mass spectrometry; IDO:symbiont host role 2020-07
MTBLS1168 MetaboLights Supplementation of Bacillus sp. DU-106 reduces hypercholesterolemia and ameliorates gut dysbiosis in high-fat diet rats Pan Li (South China Agricultural University) Rattus norvegicus NCIT:Hypercholesterolemia; EFO:high fat diet; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCBITAXON:Bacillus sp. DU-106; CHMO:tandem mass spectrometry 2021-04
MTBLS1196 MetaboLights New insights into the responses of soil microorganisms to polycyclic aromatic hydrocarbon stress by combining enzyme activity and sequencing analysis with metabolomics Li Xiaona (Institute of soil science) soil CHEBI:environmental contaminant; ENVO:microbial community; CHMO:gas chromatography time-of-flight mass spectrometry; NCIT:Polycyclic Aromatic Hydrocarbons; ENVO:soil environment 2021-02
MTBLS1191 MetaboLights Absence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii Yu Wenjing (Hainan University) Aeromonas veronii MTBLS:untargeted metabolites; NCIT:Transfer-messenger rna; MTBLS:cefotaxime; CHMO:Ultra-performance liquid chromatography-mass spectrometry 2020-01
MTBLS1188 MetaboLights Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum Clement Regnault (Glasgow Polyomics) Homo sapiens::Sample preparation blank WHO-ART:MALARIA; IDOMAL:PfEMP-1; IDOMAL:antigenic variation; Severe disease; IDOMAL:immune response; CHMO:high-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MTBLS:Glasgow Polyomics 2020-12
MTBLS1187 MetaboLights Aroma and quality of breads baked from old and modern wheat varieties and their prediction from genomic and flour-based metabolite profiles Dominik Brilhaus (Heinrich Heine University - CEPLAS Plant Metabolism and Metabolomics Laboratory ) Triticum aestivum::Sample preparation blank::Standard NCIT:Odor; MTBLS:untargeted metabolites; NCIT:Flavor; NCIT:Wheat; CO_356:Yield; MTBLS:Genomic Prediction; CHMO:Gas chromatography-mass spectrometry 2019-11
MTBLS1183 MetaboLights UPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis Xing Lei (South China University of Technology) Homo sapiens NCIT:Inflammatory Bowel Disease; NCIT:Lipidomics; CHEBI:biomarker; OMIT:Metabolic Networks and Pathways; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2021-10
MTBLS1198 MetaboLights Seawater Analysis by Ambient Mass Spectrometry-Based Seaomics NICOLAS ZABALEGUI (CIBION-CONICET) Sea water::Reference compound::Quality control::Solvent blank::Blank sample MTBLS:Seaomics; MTBLS:Untargeted Metabolomics; MTBLS:Ambient Mass Spectrometry; CHMO:direct analysis in real time mass spectrometry; MTBLS:Sea Surface Microlayer; MTBLS:Dissolved Organic Matter; MTBLS:Multivariate Statistical Analysis; MTBLS:Secondary Organic Aerosol formation 2020-05
MTBLS1209 MetaboLights Disease progression-associated alterations in fecal metabolites in SAMP1/YitFc mice, a Crohn’s disease model Yosuke Komatsu (Morinagamilk Industry Co.,Ltd.) Mus musculus CHMO:nuclear magnetic resonance spectroscopy; MTBLS:untargeted metabolites; EFO:Crohn's disease; EFO:inflammatory bowel disease; MTBLS:Gut Microbiota 2020-02
MTBLS1206 MetaboLights A Metabolomic Approach for Predicting Diurnal Changes in Cortisol Jarrett Eshima (Arizona State University) Blank::Homo sapiens::reference compound CHEBI:volatile organic compound; MTBLS:untargeted metabolites; CHEBI:cortisol; MTBLS:two-dimensional gas chromatography mass spectrometry; EFO:mental health; EFO:circadian rhythm; CHMO:headspace solid-phase micro-extraction; NCIT:Personalized Medicine; ECOCORE:diurnal 2021-09
MTBLS1217 MetaboLights Stable Isotope–Assisted Plant Metabolomics: Combination of Global and Tracer-Based Labeling for Enhanced Untargeted Profiling and Compound Annotation Christoph Bueschl (iBAM / IFA Tulln / BOKU) Triticum aestivum untargeted metabolites; CHEBI:phenylalanine; CHEBI:tryptophan; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:labelling; CHMO:tandem mass spectrometry 2020-02
MTBLS1223 MetaboLights NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome (Intracellular UPLC-MS assay) Sofie Lautrup (University of Oslo, Akershus University Hospital) Homo sapiens MTBLS:targeted metabolites; CHMO:Ultra-performance liquid chromatography-mass spectrometry; EFO:Werner syndrome; CHEBI:NAD(+); EFO:aging; GO:mitophagy; endometabolome 2019-10
MTBLS1221 MetaboLights NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome (Extracellular UPLC-MS assay) HoJoon Lee (Yale School of Medicine) blank::Homo sapiens MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:Werner syndrome; CHEBI:NAD(+); EFO:aging; GO:mitophagy; exometabolome 2019-10
MTBLS1219 MetaboLights Impact of the used solvent on the reconstitution efficiency of evaporated biosamples for untargeted metabolomics studies SaschaK Manier (Saarland University) Homo sapiens BAO:reconstitution method; MTBLS:untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; NCIT:Recovery 2021-10
MTBLS1210 MetaboLights What CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines Harald Schoeny (Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringerstrasse 38, 1090 Vienna, Austria) Cricetulus griseus::solvent blank::experimental blank MTBLS:CHO cells; MTBLS:Shotgun lipidomics; MTBLS:Protein amino acid analysis; MTBLS:Lipidomics; MSIO:flux balance analysis; MTBLS:targeted metabolites; MTBLS:liquid chromatography-tandem mass spectrometry; MTBLS:high-performance liquid chromatography-mass spectrometry; CHMO:gas chromatography-tandem mass spectrometry 2020-07
MTBLS1225 MetaboLights Sacha inchi oil alleviates gut microbiota dysbiosis and improves hepatic lipid dysmetabolism in high-fat diet-fed rats Pan Li (South China Agricultural University) Rattus norvegicus::blank MTBLS:untargeted metabolites; MTBLS:Sacha inchi (Plukenetia volubilis L.) oil; OHMI:rat gut microbiome interaction; CHMO:ultra-performance liquid chromatography-mass spectrometry; EFO:high fat diet 2022-02
MTBLS1228 MetaboLights Hyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells Charandeep Singh (Cole eye institute, Cleveland Clinic) Mus musculus::Homo sapiens ZECO:Hyperoxia; MTBLS:Metabolism 2020-03
MTBLS1257 MetaboLights Antibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function Matthew Glover (AstraZeneca) blank::Mus musculus EFO:Microbiome; CHEBI:short-chain fatty acid; CHEBI:Bile acids; MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; OMIT:Antibodies, Monoclonal 2021-01
MTBLS1266 MetaboLights MetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Mouse liver assays) guoshou teo (National University of Singapore) Mus musculus MTBLS:untargeted metabolites; NCIT:Data Extraction; NCIT:Tool; NCIT:Data-Dependent Acquisition; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2021-11
MTBLS1259 MetaboLights Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism Fengjie Huang (Shanghai Jiao Tong University Affiliated Six People's Hospital) Mus musculus::Homo sapiens MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Hypercholesterolemia; NCBITAXON:Microbiota; CHEBI:bile acid; CHMO:tandem mass spectrometry 2021-11
MTBLS1274 MetaboLights Organic Acids Modulate Systemic Metabolic Perturbation Caused by Salmonella Pullorum Challenge in Early-Stage Broilers Jing Wang (Feed Research Institute, Chinese Academy of Agricultrue Sciences) Gallus gallus NCIT:Salmonella enterica subsp. enterica Serovar Pullorum; CHEBI:organic acid; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Broiler Chicken 2021-05
MTBLS1285 MetaboLights Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells (LC-MS) Ratnasekhar Ch (School of Biological Sciences, Queen's University Belfast & UCL) Homo sapiens OMIT:Metabolome; MTBLS:untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; GO:circadian rhythm; MTBLS:redox 2020-11
MTBLS1267 MetaboLights Metabolomics Characterization of Human Calcific Aortic Valve Stenosis Aneesh Kumar (RGCB) Homo sapiens MTBLS:untargeted metabolites; MTBLS:Calcific aortic valve stenosis; CHMO:Ultra-performance liquid chromatography-mass spectrometry; EFO:Heart valve disease; EPO:surgical treatment; CHMO:Ion mobility spectrometry-mass spectrometry 2020-02
MTBLS1282 MetaboLights Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development Lena Lampe (Francis Crick Institute) Anopheles gambiae MTBLS:untargeted metabolites; NCBITAXON:Plasmodium falciparum; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:gas chromatography-mass spectrometry; MC:reproductive (estrous) cycle; NCIT:Parasite; OBI:blood meal source role 2021-11
MTBLS1275 MetaboLights A pathogen-specific isotope tracing approach reveals metabolic activities and fluxes of intracellular Salmonella Karin Mitosch (EMBL Heidelberg) Mus musculus::Homo sapiens::Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S MTBLS:untargeted metabolites; EDAM:Fluxomics; EFO:pathogen; EFO:infection; BTO:macrophage; CL:epithelial cell; NCBITAXON:Salmonella enterica subsp. enterica serovar Typhimurium; CHMO:ultra-performance liquid chromatography-mass spectrometry 2023-08
MTBLS1286 MetaboLights Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells (GC-MS) Ratnasekhar Ch (School of Biological Sciences, Queen's University Belfast & UCL) reference compound mix::Homo sapiens::experimental blank CL:Erythrocyte; MTBLS:untargeted metabolites; OBI:gas chromatography mass spectrometry; GO:circadian rhythm; MTBLS:redox 2020-11
MTBLS1295 MetaboLights Gut Microbiota Dysbiosis is Associated with Altered Bile Acid Metabolism in Infantile Cholestasis Xuefeng Gao (Shenzhen University General Hospital) Homo sapiens::blank MTBLS:targeted metabolites; NCIT:Cholestasis; MTBLS:Impaired hepatic function; MTBLS:BioSamples 2019-11
MTBLS1302 MetaboLights Revealing the constituents of Egypt’s oldest beer using infrared and mass spectrometry Moamen Elmassry (Texas Tech University) Hordeum vulgare;NCBITAXON:Hordeum vulgare;NCBITAXON:Hordeum vulgare;NCBITAXON:Triticum dicoccon;NCBITAXON:Triticum aestivum;EFO:Triticum durum CHMO:gas chromatography-mass spectrometry; untargeted metabolites; GSSO:Ancient Egypt; IOBC:brewing; CHEBI:volatile organic compound; CHMO:headspace solid-phase micro-extraction 2020-01
MTBLS1301 MetaboLights Untargeted metabolomics workshop report: quality control considerations from sample preparation to data analysis Prasad Phapale (EMBL) Mus musculus MTBLS:Metabolomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:workshop; MTBLS:untargeted metabolites; MTBLS:quality control; MTBLS:Lipidomics 2020-12
MTBLS1309 MetaboLights Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. congolense assay) Daniel Paape (University of Glasgow ) blank::Trypanosoma congolense CHEBI:benzoxaborole; MTBLS:targeted metabolites; CHMO:Liquid chromatography mass spectrometry; Trypanosoma vivax; MTBLS:drug resistance; CHEBI:prodrug 2020-10
MTBLS1320 MetaboLights A multi-omics dataset of heat-shock response in the yeast RNA binding protein Mip6 (NMR assay) Susana RodriguezNavarro (Instituto de Biomedicina de Valencia - CSIC) Saccharomyces cerevisiae MTBLS:targeted metabolites; CHMO:Nuclear magnetic resonance spectroscopy; MTBLS:Heat shock treatment; MTBLS:mip6 mutant 2020-02
MTBLS1311 MetaboLights MetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Standard mixture assay) guoshou teo (National University of Singapore) reference compound MTBLS:untargeted metabolites; NCIT:Data Extraction; NCIT:Tool; NCIT:Data-Dependent Acquisition; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2021-11
MTBLS1264 MetaboLights Bioaccumulation of therapeutic drugs by human gut bacteria (B.animalis assays) Sergej Andrejev (EMBL) Bacteroides vulgatus::Escherichia coli ED1a::Coprococcus comes::Bifidobacterium animalis subsp. lactis::Lactobacillus plantarum::experimental blank::Bifidobacterium longum subsp. infantis::Bacteroides thetaiotaomicron::[Ruminococcus] torques::Fusobacterium nucleatum subsp. nucleatum::Clostridium ramosum::[Clostridium] saccharolyticum WM1::Eggerthella lenta::Lactobacillus paracasei::Bacteroides fragilis::Lactococcus lactis::Eubacterium rectale::Bifidobacterium longum subsp. longum::Lactobacillus gasseri::[Ruminococcus] gnavus::Streptococcus salivarius::Escherichia coli IAI1::Bacteroides uniformis::Clostridium bolteae MTBLS:HRMS; MTBLS:targeted metabolites; MTBLS:ultra-performance liquid chromatography-mass spectrometry; MTBLS:bioaccumulation; OHMI:human gut microbiome 2021-07
MTBLS1326 MetaboLights Metabolomics of red-light-induced stomatal opening in Arabidopsis thaliana: Coupling with abscisic acid and jasmonic acid metabolism Mengmeng Zhu (Pennsylvania state university) Arabidopsis thaliana MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:abscisic acid; CHEBI:jasmonic acid; PECO:red light exposure; CHMO:tandem mass spectrometry 2022-01
MTBLS1333 MetaboLights LipidCreator workbench to probe the lipidomic landscape - Collision Energy Optimization and Fragment Intensity Prediction for Lipid Mediators, Thermo QExactive HF Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) reference compound MTBLS:Direct Infusion Mass Spectrometry; MTBLS:targeted metabolites; NCIT:Lipidomics; MTBLS:Spectral library 2020-04
MTBLS1334 MetaboLights LipidCreator workbench to probe the lipidomic landscape - Collision Energy Optimization and Fragment Intensity Prediction for Lipid Mediators, Agilent QTof Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) reference compound MTBLS:targeted metabolites; MTBLS:Direct Infusion Mass Spectrometry; MTBLS:Lipidomics; MTBLS:spectral library 2020-04
MTBLS1319 MetaboLights Bioaccumulation of therapeutic drugs by human gut bacteria: duloxetine accumulation at different concentrations (L.saccharolytica;E.coli assays) Prasad Phapale (EMBL) Lacrimispora saccharolytica::Escherichia coli IAI1::experimental blank MTBLS:HRMS; MTBLS:targeted metabolites; MTBLS:ultra-performance liquid chromatography-mass spectrometry; MTBLS:bioaccumulation; OHMI:human gut microbiome 2021-07
MTBLS1355 MetaboLights Historical Biobanks in Breast Cancer Metabolomics - Challenges and Opportunities TorfinnStve Madssen (Norwegian University of Science and Technology) Homo sapiens CHMO:magic angle spinning nuclear magnetic resonance spectroscopy; MTBLS:untargeted metabolites; EFO:breast cancer; EDAM:Biobank 2022-01
MTBLS1357 MetaboLights Four Weeks of Probiotic Supplementation Alters the Metabolic Perturbations Induced by Marathon Running: Insight from Metabolomics MarieMargaret Phelan (University of Liverpool) Homo sapiens NCIT:Running; MTBLS:Marathon athletic event; NCBITAXON:probiotic metagenome; NCIT:Gastrointestinal; MTBLS:untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2021-09
MTBLS1358 MetaboLights Stable Isotope-Assisted Metabolomics for Deciphering Xenobiotic Metabolism in Mammalian Cell Culture Mira Flasch (University of Vienna) blank::Homo sapiens::reference compound NCIT:Cell line; CHMO:Ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; EFO:xenobiotic; CHEBI:Deoxynivalenol; PDQ:stable isotope tracer study 2020-04
MTBLS1369 MetaboLights LipidCreator workbench to probe the lipidomic landscape - Platelet isolation and stimulation, Targeted Phospho and Glycerolipid Profiling Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) Homo sapiens::Solvent blank::Blank sample::Reference compound mix MTBLS:Lipidomics; CHMO:Ultra-performance liquid chromatography-mass spectrometry; MTBLS:targeted metabolites 2020-04
MTBLS1359 MetaboLights Metabolomic Signature of Early Vascular Aging (EVA) in Hypertension Renata Bujak (Medical University of Gdansk) Homo sapiens MTBLS:untargeted metabolomics; MTBLS:early vascular aging; EFO:Arterial stiffness measurement; NCIT:Pulse wave velocity; NCIT:Phospholipid metabolism; CHMO:Liquid chromatography-mass spectrometry 2020-01
MTBLS1376 MetaboLights LipidCreator workbench to probe the lipidomic landscape - Targeted lipidomics analysis of S. cerevisiae to determine true and false identification Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) Saccharomyces cerevisiae NCIT:Lipidomics; MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2020-04
MTBLS1371 MetaboLights Laser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening Simon Cameron (Queen's University Belfast) Homo sapiens EFO:cervical cancer; NCIT:Screening; NCIT:Liquid-Based Cytology; EFO:human papilloma virus infection; MTBLS:untargeted metabolites; NCIT:Cervical Intraepithelial Neoplasia; MTBLS:Rapid Evaporative Ionisation Mass Spectrometry 2022-02
MTBLS1375 MetaboLights LipidCreator workbench to probe the lipidomic landscape - Targeted lipidomics analysis of Human Plasma samples and comparison with NIST SRM 1950 standard Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) Homo sapiens MTBLS:targeted metabolites; MTBLS:Lipidomics; MTBLS:ultra-performance liquid chromatography-mass spectrometry 2020-04
MTBLS1383 MetaboLights Endoplasmic reticulum-derived bodies enable a single-cell chemical defense in Brassicaceae plants Kenji Yamada (Małopolska Centre of Biotechnology, Jagiellonian University) Arabidopsis thaliana untargeted metabolites; CHEBI:Glucosinolate; MESH:beta-Glucosidase; CHMO:liquid chromatography-mass spectrometry; UPA:plant chemical defense 2020-02
MTBLS1382 MetaboLights LipidCreator workbench to probe the lipidomic landscape - Platelet isolation and stimulation - DIA lipid mediator validation Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) Homo sapiens::Solvent blank::Reference compound mix MTBLS:untargeted metabolites; MTBLS:Lipidomics; CHMO:Ultra-performance liquid chromatography-mass spectrometry 2020-04
MTBLS1370 MetaboLights Metabolomic and Metataxonomic Fingerprinting of Human Milk Suggests Compositional Stability over a Natural Term of Breastfeeding to 24 Months Simon Cameron (Queen's University Belfast) Homo sapiens::Bos taurus MTBLS:Rapid Evaporative Ionisation Mass Spectrometry; MTBLS:untargeted metabolites; SRAO:Metataxonomics; NCIT:Breast Feeding; NCIT:Bottle Feeding 2022-02
MTBLS1381 MetaboLights LipidCreator workbench to probe the lipidomic landscape - Platelet isolation and stimulation, targeted lipid mediator profiling Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) Reference compound mix::Homo sapiens::Blank sample::Solvent blank MTBLS:targeted metabolites; MTBLS:Lipidomics; CHMO:Ultra-performance liquid chromatography-mass spectrometry 2020-04
MTBLS1386 MetaboLights Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis Lise VanWyngene (Inflammation Research Center, VIB) blank::Mus musculus::reference compound MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; MESH:Fibric Acids; NCIT:Lipidomics; IOBC:Lipotoxicity; EFO:sepsis; NCIT:Liver Dysfunction 2020-01
MTBLS1390 MetaboLights Cell-based and multi-omics profiling reveal dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei Clement Regnault (University of Glasgow) blank sample::Trypanosoma brucei MESH:Trypanosoma; OBI:mitochondrion; MESH:Metabolism; CL:signaling; MESH:Reactive Oxygen Species; differentiation; CHMO:hydrophilic interaction chromatography; CHMO:liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2020-08
MTBLS1391 MetaboLights Characterization of Cabernet Sauvignon Wines by Untargeted HS-SPME GC-QTOF-MS Alejandra ChavezMarquez (Centro de Investigacion en Alimentacion y Desarrollo, AC) blank::Vitis vinifera MTBLS:Mexican wine; CHMO:gas chromatography-mass spectrometry; MTBLS:untargeted metabolites; CHMO:headspace solid-phase micro-extraction; MTBLS:Wine aroma; CHEBI:volatile organic compound 2022-04
MTBLS1388 MetaboLights Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges Karin Steffen (Uppsala University) Weberella bursa::Geodia barretti::Heteroscleromorpha::Stryphnus fortis MTBLS:sponge ground; MTBLS:marine sponge; GAZ:Davis Strait; CHMO:ultra-performance liquid chromatography-mass spectrometry; EDAM:Microbial ecology; EFO:microbiome; MTBLS:untargeted metabolites 2023-05
MTBLS1407 MetaboLights Aging markers in human urine: A comprehensive, non-targeted LC-MS study Takayuki Teruya (OIST) Homo sapiens NCIT:Aging; MTBLS:untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry 2020-10
MTBLS1410 MetaboLights Metabolic alterations caused by the mutation and overexpression of the Tmem135 gene Vijesh Bhute (University of Cambridge) Mus musculus OMIM:TRANSMEMBRANE PROTEIN 135; MTBLS:untargeted metabolites; MTBLS:nuclear magnetic resonance spectroscopy; MESH:Mice; MESH:Mice, Transgenic; MESH:Mice, Mutant Strains; MESH:Mitochondrial Dynamics; CLO:heart; EHDAA:pigmented retinal epithelium; CL:cerebellum; APAONTO:Hippocampus 2021-02
MTBLS1399 MetaboLights Energy-stress-mediated AMPK activation inhibits ferroptosis Fereshteh Zandkarimi (Columbia University) Mus musculus::Homo sapiens::Solvent blank GO:ferroptosis; NCIT:Lipidomics; GO:Amp-activated protein kinase activity; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2023-01
MTBLS1402 MetaboLights Untargeted metabolomics links glutathione to bacterial cell cycle progression Johannes Hartl (Charité Berlin) Caulobacter vibrioides MTBLS:untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; GO:cell cycle 2020-10
MTBLS1411 MetaboLights Hfq Regulates Efflux Pump Expression and Purine Metabolic Pathway to Increase the Trimethoprim Resistance in Aeromonas veronii Dan Wang (Hainan University) Aeromonas veronii MTBLS:untargeted metabolites; OGG:hfq; NCIT:Purine Metabolism Pathway; IOBC:Trimethoprim Resistance; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-02
MTBLS1396 MetaboLights Longitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome Yi Yang (Imperial College London) Reference compound::NMR buffer::Homo sapiens::experimental blank::solvent blank MTBLS:irritable bowel syndrome; CHEBI:bile acid; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MTBLS:targeted metabolites 2020-09
MTBLS1432 MetaboLights Changes in lipid profiles of epileptic mouse model Alicia Johnson (University of Nebraska-Lincoln) Mus musculus EFO:epilepsy; NCIT:Lipidomics; MTBLS:untargeted metabolites; NCIT:Voltage-Gated Potassium Ion Channel Activation; CHMO:ultra-performance liquid chromatography-mass spectrometry 2022-01
MTBLS1416 MetaboLights NMR-based metabolomic profile of hypercholesterolemic human sera: Relationship with in vitro gene expression? AnnaMaria DUrsi (University of Salerno) Homo sapiens MTBLS:untargeted metabolites; GEXO:HMGCS2; MEDDRA:Dyslipidaemia; CHMO:nuclear magnetic resonance spectroscopy; MESH:Ketone Bodies; ICPC2P:hypercholesterolaemia; CHEBI:2-hydroxybutyrate; CHEBI:acetate; CHEBI:acetone 2020-05
MTBLS1430 MetaboLights Highly sensitive feature detection for high resolution LC/MS Steffen Neumann (Leibniz Institute of Plant Biochemistry) Arabidopsis thaliana::reference compound EFO:spike-in quality control role; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2020-01
MTBLS1405 MetaboLights Metabolite signatures of diverse Camellia sinensis tea populations Xiaomin Yu (Fujian Agriculture and Forestry University) Camellia sinensis MTBLS:untargeted metabolites; MESH:Tea; CHEBI:flavonoid; CHMO:ultra-performance liquid chromatography-mass spectrometry; secondary leaf 2020-10
MTBLS1437 MetaboLights Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients Gwenaelle LeGall (University of East Anglia) Mus musculus CHMO:Nuclear magnetic resonance spectroscopy; CHMO:one-dimensional nuclear magnetic resonance spectroscopy; CHMO:two-dimensional nuclear magnetic resonance spectroscopy; MTBLS:untargeted metabolites; NCIT:Intestinal Flora 2021-12
MTBLS1435 MetaboLights Metabolomic analysis of synovial fluid from Thoroughbred racehorses diagnosed with palmar osteochondral disease using magnetic resonance imaging MarieMargaret Phelan (University of Liverpool) Equus caballus MTBLS:untargeted metabolites; NCIT:Horse; NCIT:Metacarpophalangeal joint; NCIT:Magnetic resonance imaging; EFO:Palmar fibromatosis; CHMO:nuclear magnetic resonance spectroscopy 2021-11
MTBLS1443 MetaboLights Use of untargeted LC-MS metabolome to discriminate Italian mono-varietal red wines, produced in their different terroirs Panagiotis Arapitsas (Fondazione Edmund Mach) Vitis vinifera untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:biomarker; MEO:red wine; oenology 2020-04
MTBLS1463 MetaboLights Plant hosts modify belowground microbial community response to extreme drought Nancy Engle (Oak Ridge National Laboratory) Populus trichocarpa CO_333:Drought stress; CHMO:Gas chromatography mass spectrometry; MTBLS:untargeted metabolites; MTBLS:soil microbiome 2020-06
MTBLS1452 MetaboLights 1H NMR metabolomic and transcriptomic analyses reveal urinary metabolites as biomarker candidates in response to protein undernutrition in adult rats Yosuke Komatsu (Morinagamilk Industry Co.,Ltd.) Rattus norvegicus MTBLS:untargeted metabolites; CHMO:1H nuclear magnetic resonance spectroscopy; OBCS:multivariate analysis; EFO:protein energy malnutrition; MTBLS:Transcriptomics; MTBLS:Urinary metabolite 2021-05
MTBLS1455 MetaboLights A data set of 255000 randomly selected and manually classified extracted ion chromatograms for evaluation of peak detection methods Tobias Schulze (Helmholtz Centre for Environmental Research - UFZ) waste treatment plant::tributary::calibration solution::blank sample::river MTBLS:gap filling; MTBLS:peak detection; FBcv:Dataset descriptor; MTBLS:Computational mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2020-05
MTBLS1446 MetaboLights Phospholipid acyl chain diversity controls the tissue-specific assembly of mitochondrial cardiolipins Gregor mer (Medical University Innsbruck) Reference compound::Mus musculus MTBLS:Lipidomics; CHEBI:Cardiolipin; MTBLS:high-performance liquid chromatography-mass spectrometry; OMIT:Mitochondria; MTBLS:targeted metabolites 2020-05
MTBLS1474 MetaboLights Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. brucei assay) Clement Regnault (University of Glasgow) blank sample::Trypanosoma brucei MTBLS:targeted metabolites; CHMO:liquid chromatography-mass spectrometry; CHEBI:benzoxaborole; MESH:serine carboxypeptidase; MESH:Drug Resistance 2020-09
MTBLS1464 MetaboLights Disease phenotype prediction in multiple sclerosis Stephanie Herman (Uppsala University) Homo sapiens::blank DOID:multiple sclerosis; CHMO:high-performance liquid chromatography-mass spectrometry; OMIT:Precision Medicine; MTBLS:untargeted metabolites; CHEBI:biomarker 2023-05
MTBLS1485 MetaboLights 3D Imaging and metabolomic profiling reveal higher neuroactive kavalactone contents in lateral roots and crown root peels of Piper methysticum (kava) Yogini Jaiswal (North Carolina A&T state University) blank::Piper methysticum::reference compound CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MTBLS:Plant Metabolomics; MTBLS:kavalactone; CHMO:Gas chromatography mass spectrometry 2020-10
MTBLS1490 MetaboLights Effect of L-carnitine administration on lipid and metabolite content in sheep infraspinatus muscle after tendon release Martin Flck (University of Zurich) Ovis aries OBI:metabolite profiling; MS:Genespring MS; GALEN:Surgery; ICNP:Drug; MTBLS:l-carnitine; MTBLS:contralateral muscle; CHMO:Ultra-performance liquid chromatography-mass spectrometry 2020-07
MTBLS1465 MetaboLights Assessment of human plasma and urine sample preparation for re-producible and high-throughput UHPLC-MS clinical metabolic phenotyping Ralf Weber (University of Birmingham) blank::Homo sapiens ERO:Metabolic phenotyping; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:Sample Preparation; NCIT:Lipidomics; untargeted metabolites 2020-08
MTBLS1481 MetaboLights Toxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts SaschaK Manier (Saarland University) Homo sapiens CHMO:liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MTBLS:untargeted metabolites; MTBLS:toxicometabolomics; CHEBI:psychotropic drug 2023-10
MTBLS1495 MetaboLights Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study JakeOwen Ellis (Liverpool University) Equus caballus EFO:osteoarthritis; MTBLS:untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy 2020-09
MTBLS1503 MetaboLights Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly Xiaotao Shen (Chinese Academy of Sciences) Mus musculus MTBLS:SNARE; MTBLS:Lipidomics; MTBLS:In-cell NMR; MTBLS:Lipid raft; CHMO:Ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2021-10
MTBLS1488 MetaboLights Resolvin E1 in follicular fluid acts as a potential biomarker and improves oocyte developmental competence by optimizing cumulus cells Zhongyi Zhu (Fudan University ) Homo sapiens CHEBI:Resolvin e1; BTO:Follicular fluid; BTO:Oocyte; MTBLS:RvE1; CHMO:ultra-performance liquid chromatography-mass spectrometry 2020-03
MTBLS1507 MetaboLights Metabolic memory underlying minimal residual disease in breast cancer Eleni Kafkia (EMBL, Heidelberg) Mus musculus EFO:breast cancer; NCIT:Minimal Residual Disease; MTBLS:targeted metabolites; multi-omics analysis; CHEBI:isotopic tracer; CHMO:gas chromatography-mass spectrometry 2021-09
MTBLS1497 MetaboLights RA-MAP: mapping the molecular immunological landscape in early rheumatoid arthritis with vaccine controls Stephen Young (University of Birmingham) Homo sapiens MTBLS:untargeted metabolites; EFO:rheumatoid arthritis; BTO:serum; BTO:urine; NCIT:Pathogenesis; CHMO:nuclear magnetic resonance spectroscopy 2021-06
MTBLS1509 MetaboLights Strong effect of Penicillium roqueforti populations on volatile and metabolic compounds responsible for aromas, flavour and texture in blue cheeses Antoine Branca (University Paris-Saclay) Ovis aries::blank::reference compound MTBLS:untargeted metabolites; CHEBI:volatile organic compound; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:thermal desorption-gas chromatography mass spectrometry; FOODON:roquefort cheese; NCBITAXON:Bacteria; MTBLS:food quality 2021-10
MTBLS1517 MetaboLights Combined metabolomics with transcriptomics reveals important serum biomarkers correlated with lung cancer proliferation through calcium signaling pathway Zhuoru He (Guangzhou University of Chinese Medicine) Homo sapiens MTBLS:Metabolomics; CHMO:GC-MS; MTBLS:lung cancer; MTBLS:biomarker 2025-04
MTBLS1518 MetaboLights Post-mortem changes in metabolomic profiles of human serum, aqueous humor and vitreous humor Yuri Tsentalovich (ITC SB RAS) Homo sapiens untargeted metabolites; MESH:Postmortem Changes; CHMO:nuclear magnetic resonance spectroscopy 2021-02
MTBLS1537 MetaboLights Toxoplasma gondii infection induces metabolic alterations in the mouse cerebellum Junjun He (CAAS) Mus musculus MTBLS:untargeted metabolites; CHMO:Ultra-performance liquid chromatography-mass spectrometry; NCBITAXON:Toxoplasma gondii; SYMP:Behavioral symptom; EFO:Parasitic infection 2020-04
MTBLS1540 MetaboLights Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility Kameda Masahiro (Kyoto University Hospital) Homo sapiens RH-MESH:Frail Elderly; EFO:blood; MTBLS:untargeted metabolites; CHMO:liquid chromatography-mass spectrometry 2020-05
MTBLS1531 MetaboLights Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment Nils Hoffmann (IBG-5, Forschungszentrum Jülich, Bielefeld, Germany) Rattus norvegicus::Mus musculus MTBLS:Synaptic junction; NCIT:Lipidomics; MTBLS:enriched environment; MTBLS:multiomics; MTBLS:Direct Infusion Mass Spectrometry; CHEBI:endocannabinoid; CHMO:tandem mass spectrometry; MTBLS:untargeted metabolites 2021-09
MTBLS1544 MetaboLights Resource Partitioning of Diatom Metabolites that Support Bacterial Heterotrophy in the Ocean (NMR assay) Nicole Holderman (University of Georgia) Thalassiosira pseudonana;NCBITAXON:Polaribacter dokdonensis::Thalassiosira pseudonana::Thalassiosira pseudonana;NCBITAXON:Ruegeria pomeroyi::Thalassiosira pseudonana;NCBITAXON:Stenotrophomonas sp. SKA14::blank CHMO:nuclear magnetic resonance spectroscopy; OMIT:Heterotrophic Processes; OMIT:Diatoms; MSIO:polar metabolite extraction; CHMO:heteronuclear single quantum coherence; MTBLS:untargeted metabolites; CHEBI:marine metabolite; MTBLS:dissolved organic matter 2020-09
MTBLS1550 MetaboLights Metabolomics analysis identifies metabolites associated with systemic acquired resistance in Arabidopsis Qian zhouqianomicsspacecom (Shanghai omicsspace Biotech Co.,Ltd.) blank::Arabidopsis thaliana MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; GO:Systemic acquired resistance; CHEBI:Amino acid; CHEBI:Phenols 2020-05
MTBLS1558 MetaboLights Lipid Profiles of Human Brain Tumors Obtained by High-Resolution Negative Mode Ambient Mass Spectrometry Denis Zavorotnyuk (MIPT) Homo sapiens Direct Infusion Mass Spectrometry; NCIT:Brain Tumor Surgery; untargeted metabolites; MESH:Drug Resistant Epilepsy; spray-from-tissue ionization; CHMO:Fourier transform ion cyclotron resonance mass spectrometry 2021-11
MTBLS1541 MetaboLights The maturity in fetal pigs using a multi-fluid metabolomic approach Galle Lefort (INRAE) blank::Sus scrofa CHMO:nuclear magnetic resonance spectroscopy; MTBLS:untargeted metabolites; NCIT:Perinatal Mortality; PATO:maturity 2020-07
MTBLS1569 MetaboLights The killing mechanism of teixobactin against methicillin-resistant Staphylococcus aureus (MRSA): An untargeted metabolomics study Maytham Hussein (Melbourne University) Staphylococcus aureus MTBLS:Metabolomics; NCBITAXON:Staphylococcus aureus; MTBLS:Teixobactin; MTBLS:MRSA; MTBLS:high-performance liquid chromatography-mass spectrometry 2020-04
MTBLS1561 MetaboLights Improvement of prediction ability by integrating multi-omic datasets in barley Dominik Brilhaus (Heinrich Heine University - CEPLAS Plant Metabolism and Metabolomics Laboratory ) blank::reference compound::Hordeum vulgare MTBLS:untargeted metabolites; NCIT:Barley; STATO:Genome Wide Association Study; CHMO:gas chromatography-mass spectrometry; MTBLS:Genomic prediction; OMIT:Plant Breeding 2022-03
MTBLS1565 MetaboLights Untargeted metabolomics as a hypothesis-generation tool in plant protection product discovery: Highlighting the potential of trehalose and glycerol metabolism of fungal conidiospores as novel targets Ioannis Kalampokis (Agricultural University of Athens) Aspergillus nidulans conidial germination; CHMO:gas chromatography-mass spectrometry; untargeted metabolites; MTBLS:Osmoregulators; CHEBI:fungal metabolite 2020-09
MTBLS1572 MetaboLights Comparison of Full-Scan, Data-Dependent, and Data-Independent Acquisition Modes in Liquid Chromatography-Mass Spectrometry Based Untargeted Metabolomics Jian Guo (UBC) Homo sapiens::blank::reference compound MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-05
MTBLS1579 MetaboLights Seagrass excretes sugars to their rhizosphere making them the sweet spots in the sea (Plant tissues; GC-MS assay) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Posidonia oceanica ENVO:sea grass bed; MTBLS:Sucrose; CHMO:gas chromatography-mass spectrometry; MTBLS:untargeted metabolites 2022-01
MTBLS1559 MetaboLights Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis Robert Jansen (Weill Cornell Medicine) Mycobacterium bovis bcg::Mycobacterium tuberculosis PR:Aspartate aminotransferase; MTBLS:mycobacterium tuberculosis; MTBLS:Functional gene annotation; UPaUPA:Nitrogen metabolism; CHMO:High-performance liquid chromatography-mass spectrometry 2020-05
MTBLS1570 MetaboLights Seagrass excretes sugars to their rhizosphere making them the sweet spots in the sea (Seawater sediment; GC-MS assay) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Marine sediment ENVO:sea grass bed; CHMO:gas chromatography-mass spectrometry; MTBLS:Porewater; MTBLS:13C- Incubation; MTBLS:untargeted metabolites; CHEBI:isotopic tracer 2022-01
MTBLS1584 MetaboLights Plasma Lipid Profile Reveals Plasmalogens as Potential Biomarkers for Colon Cancer Screening AnnaMaria Fernandes (UNIVERSIDADE SÃO FRANCISCO - BRAGANÇA PAULISTA) Homo sapiens EFO:colon carcinoma; NCIT:Lipidomics; CHEBI:biomarker; NCIT:Plasmalogen; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2023-11
MTBLS1606 MetaboLights Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent Bart Cuypers (University Of Antwerp) Leishmania donovani::blank NCIT:Virulence; NCIT:Genomics; EFO:Visceral leishmaniasis; MTBLS:untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; PRIDE:Multi-omics study; NCIT:Diversity; MTBLS:Glasgow Polyomics 2022-09
MTBLS1612 MetaboLights Four layer multi-omics reveals molecular responses to aneuploidy in Leishmania Bart Cuypers (University Of Antwerp) Leishmania donovani::blank::reference compound NCIT:Aneuploidy; CHMO:high-performance liquid chromatography-mass spectrometry; PRIDE:Multi-omics study; MTBLS:untargeted metabolites; MTBLS:Glasgow Polyomics 2022-09
MTBLS1622 MetaboLights Unknown Metabolite Annotation in Mouse Aging using Ion Mobility Collision Cross-Section Atlas (AllCCS) Zhiwei Zhou (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences) Mus musculus CHMO:Ion mobility spectrometry-mass spectrometry; EFO:aging; CHMO:ultra-performance liquid chromatography-mass spectrometry; untargeted metabolites; CHMO:tandem mass spectrometry 2020-07
MTBLS1629 MetaboLights Paternal microbiome perturbations impact offspring fitness Saravanan Devendran (EMBL) Mus musculus NCIT:Microbiome; NCIT:Offspring; NCIT:Reproductive System; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2024-02
MTBLS1636 MetaboLights Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence Howbeer Muhamadali (University of Liverpool) Aspergillus fumigatus CHMO:gas chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Methionine Synthase; CHEBI:antifungal drug 2020-10
MTBLS1642 MetaboLights Deciphering metabolomic alterations in seminal plasma of crossbred (Bos taurus X Bos indicus) bulls through comparative deep metabolomic analysis Arumugam Kumaresan (Principal Scientist, ICAR-National Dairy Research Institute, Karnal) Bos taurus MTBLS:Crossbred bull; LBO:Zebu; MTBLS:untargeted metabolites; CHMO:liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2021-12
MTBLS1610 MetaboLights Seagrass excretes sugars to their rhizosphere making them the sweet spots in the sea (Sediment porewater; GC-MS assay) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Porewater MTBLS:Porewater; CHMO:gas chromatography-mass spectrometry; ENVO:sea grass bed; MTBLS:untargeted metabolites 2022-01
MTBLS1639 MetaboLights PRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis David Papadopoli (McGill University) Extract::blank::Mus musculus::Standard MTBLS:Myc; EFO:Lymphoma; MTBLS:PRDM15; MTBLS:Zn-fingers; MTBLS:Glycolysis; MTBLS:IGF1R; MTBLS:INSR; MTBLS:PI3K/AKT/mTOR; MTBLS:targeted metabolites 2025-06
MTBLS1627 MetaboLights Bioaccumulation of therapeutic drugs by human gut bacteria (E.coli;C.saccharolyticum;S.salivarius;E.rectale;L.plantarum;L.lactis assays) Saravanan Devendran (EMBL) Clostridium saccharolyticum::Streptococcus salivarius::Lactococcus lactis subsp. lactis Il1403::Eubacterium rectale::Escherichia coli ED1a::Lactobacillus plantarum WCFS1::Escherichia coli IAI1::experimental blank MTBLS:drug; MESH:Bioaccumulation; OHMI:human gut microbiome; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2021-07
MTBLS1645 MetaboLights Metabolomic and Proteomic Stratification of Equine Osteoarthritis JakeOwen Ellis (Liverpool University) Equus caballus NCIT:Osteoarthritis; NCBITAXON:Equus caballus; NCIT:Synovial Fluid; MTBLS:Metabolomics; MTBLS:1H nuclear magnetic resonance spectroscopy; NCIT:Proteomics 2025-10
MTBLS1679 MetaboLights Contribution of fungal microbiome to intestinal physiology, early-life immune development and mucosal inflammation in mice VeronikaKuchaov Pettersen (UNIVERSITETET I TROMSØ - NORGES ARKTISKE UNIVERSITET) blank::Mus musculus NCIT:Microbiome; OHMI:host-microbiome interaction; MTBLS:untargeted metabolites; GO:adaptive immune response; NCIT:Fungal Colonization; IDOMAL:antibiotic; NCIT:Ovalbumin; CHMO:ultra-performance liquid chromatography-mass spectrometry 2022-01
MTBLS1693 MetaboLights Known Metabolite Annotation in Different Biological Samples using Ion Mobility Collision Cross-Section Atlas (AllCCS) Zhiwei Zhou (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences) Drosophila melanogaster::Mus musculus::Homo sapiens CHMO:Ion mobility spectrometry-mass spectrometry; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-07
MTBLS1692 MetaboLights Ecophysiological Study of Paraburkholderia sp. Strain 1N under Soil Solution Conditions: Dynamic Substrate Preferences and Characterization of Carbon Use Efficiency Taylor Cyle (Cornell University) Extract::Reference compound::Paraburkholderia::experimental blank ecophysiology; MTBLS:time-resolved metabolic footprinting; MTBLS:Exometabolomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:nuclear magnetic resonance spectroscopy; MTBLS:targeted metabolites 2020-09
MTBLS1684 MetaboLights A multi-omic analysis of birthweight in newborn cord blood reveals new underlying mechanisms related to cholesterol metabolism Rossella Alfano (Hasselt University) Homo sapiens CHEBI:cholesterol; NCIT:DNA Methylation; NCIT:Gene Expression; CHEBI:protein; MTBLS:untargeted metabolomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Newborn; EFO:umbilical cord 2020-06
MTBLS1698 MetaboLights Jejunal inflammatory cytokines, barrier proteins and microbiome-metabolome responses to early supplementary feeding of Bamei suckling piglets jipeng xuexi (Gansu Agricultural University) Sus scrofa MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; OMIT:Animals, Suckling; MTBLS:jejunal microbiota; MTBLS:jejunal barrier 2020-06
MTBLS1677 MetaboLights 1H NMR chemometric models for classification of Czech wine type and variety Jaroslav Havlik (CULS Prague) Vitis vinifera NCIT:Wine; CHMO:nuclear magnetic resonance spectroscopy; EDAM:Chemometrics; MTBLS:wine classification; MTBLS:randomForest; MTBLS:wine analysis 2020-08
MTBLS1708 MetaboLights Functional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming Hugo VarelaRodriguez (LANGEBIO-CINVESTAV) Ambystoma mexicanum NCIT:Ultra High-performance Liquid Chromatography/Tandem Mass Spectrometry; MTBLS:targeted metabolites 2021-11
MTBLS1715 MetaboLights Hierarchical Carbon Metabolism in Iron-Deficient Bacteria Favors Iron-Scavenging Strategy Caroll Mendonca (Cornell University) Pseudomonas putida MTBLS:Metabolomics; MTBLS:Pseudomonas; MTBLS:carbon metabolism; MTBLS:iron limitation; MTBLS:13C-assisted metabolomics; MTBLS:liquid chromatography-tandem mass spectrometry 2020-12
MTBLS1714 MetaboLights A metabolomics exploration of the sexual phase in the marine diatom Pseudo-nitzschia multistriata Federica Fiorini (HZI) Pseudo-nitzschia multistriata MTBLS:Metabolomics; MTBLS:Marine natural products; MTBLS:diatoms; MTBLS:Pseudo-nitzschia multistriata; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2020-06
MTBLS1707 MetaboLights Characterisation of monophasic solvent-based tissue extractions for detection of polar metabolites and lipids applying UHPLC-MS clinical metabolic phenotyping assays Ralf Weber (University of Birmingham) Ovis aries::blank untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; MS:sample preparation; NCIT:Lipidomics 2020-09
MTBLS1717 MetaboLights Non-targeted multimodal metabolomics and lipidomics data from ovine rumen fluid fractions Nikola Palevich (AgResearch) Ovis aries::blank::Haemonchus contortus EFO:microbiome; MTBLS:untargeted metabolites; NCIT:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MICRO:clarified rumen fluid 2021-08
MTBLS1739 MetaboLights Aftpo3 and Afdur3, the Aspergillus fumigatus Plasma Membrane Transporters of Polyamines, Regulate Polyamine Homeostasis and Itraconazole Susceptibility mingcong chen ( School of Public Health, Nanjing Medical University) Aspergillus fumigatus NCBITAXON:Aspergillus fumigatus; CHEBI:polyamine; CHEBI:azole 2020-12
MTBLS1746 MetaboLights Seagrasses excrete sugars to their rhizosphere making them the sweet spots in the sea (Plant roots; MALDI-MSI assay) Manuel Liebeke (Max Planck Institute of Marine Microbiology) Posidonia oceanica untargeted metabolites; CHMO:matrix-assisted laser desorption-ionisation imaging mass spectrometry; CHEBI:sucrose; ENVO:sea grass bed 2022-01
MTBLS1737 MetaboLights Metabolic Profiling of Volatile Organic Compounds (VOCs) Emitted by the Pathogens Francisella tularensis and Bacillus anthracis in Liquid Culture Kristen Reese (Lawrence Livermore National Laboratory) Bacillus anthracis::blank::Francisella tularensis CHEBI:volatile organic compound; CHMO:gas chromatography-mass spectrometry; EFO:pathogen; MTBLS:untargeted metabolites; CHMO:headspace solid-phase micro-extraction 2020-08
MTBLS1720 MetaboLights Viral infection of algal blooms leaves a unique metabolic footprint on the dissolved organic matter in the ocean Guy Schleyer (Weizmann Institute of Science) Quality Control Sample::marine plankton environmental sample ENVO:mesocosm; MTBLS:Phytoplankton; MTBLS:Host-Virus Interaction; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Norway; ENVO:fjord; GAZ:Raunefjorden; NCBITAXON:Emiliania huxleyi; ENVO:algal bloom; CHMO:liquid-solid extraction; MTBLS:dissolved organic matter 2021-05
MTBLS1748 MetaboLights Metabolomic Aspects of Conservative and Resistance-related Elements of Response to Fusarium culmorum in the Grass Family Anna Piasecka (Institute of Bioorganic Chemistry Polish Academy of Scinces) Brachypodium distachyon::Hordeum vulgare::Triticum aestivum CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:Fusarium head blight; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; MTBLS:plant–pathogen interaction 2022-10
MTBLS1750 MetaboLights Prokaryotic viperins produce diverse antiviral molecules Aude Bernheim (Weizmann Institute of Science) Escherichia coli OMIM:RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2; MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-08
MTBLS1751 MetaboLights Resource Partitioning of Diatom Metabolites that Support Bacterial Heterotrophy in the Ocean (UPLC-MS assay) Krista Longnecker (Woods Hole Oceanographic Institution) Thalassiosira pseudonana;NCBITAXON:Polaribacter dokdonensis::Thalassiosira pseudonana::blank::Thalassiosira pseudonana;NCBITAXON:Stenotrophomonas sp. SKA14::Thalassiosira pseudonana;NCBITAXON:Ruegeria pomeroyi CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:derivatisation; OMIT:Diatoms; OMIT:Heterotrophic Processes; MTBLS:untargeted metabolites; CHEBI:marine metabolite; MTBLS:dissolved organic matter 2020-09
MTBLS1752 MetaboLights Insights into the controls on metabolite distributions along a latitudinal transect of the western Atlantic Ocean Krista Longnecker (Woods Hole Oceanographic Institution) sea water CHMO:liquid chromatography-mass spectrometry; ENVO:sea water environment; MTBLS:targeted metabolites; MTBLS:dissolved organic matter; CHMO:tandem mass spectrometry 2021-08
MTBLS1764 MetaboLights Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth Christina Lucas (CECAD) blank::Mus musculus MTBLS:Comparative LC/MS-based profiling; ERO:ion chromatography; OGG:COX10; MTBLS:targeted metabolites 2020-06
MTBLS1757 MetaboLights Bioaccumulation of therapeutic drugs by human gut bacteria: secreted metabolite analysis for resting cells (B.uniformis;C.saccharolyticum assays) Sergej Andrejev (European Molecular Biology Laboratory) sample preparation blank::Clostridium saccharolyticum::Bacteroides uniformis::experimental blank MTBLS:untargeted metabolites; CHMO:orbitrap; CHMO:positive electrospray ionisation; MTBLS:tandem mass spectrometry; NCIT:Drug Metabolism 2021-07
MTBLS1778 MetaboLights Photosynthetic Carbon Partitioning and Metabolic Regulation in Response to Very-Low and High CO2 in Microchloropsis gaditana NIES 2587 PannagaPavan Jutur (International Centre for Genetic Engineering and Biotechnology) Microchloropsis CHEBI:carbon dioxide; MTBLS:Oleaginous Microalga; MSIO:biomass; MESH:Biofuels; MTBLS:photosynthetic cell factories; MTBLS:untargeted metabolites; MTBLS:CO2 Supplementation; MTBLS:gas chromatography-mass spectrometry 2022-01
MTBLS1755 MetaboLights Comparative metabolomics analysis of bronchial epithelium during barrier establishment after allergen exposure Juan RodriguezCoira (Universidad CEU San Pablo) Homo sapiens MTBLS:untargeted metabolite profiling; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:capillary electrophoresis-mass spectrometry; ENM:Air liquid interface; MTBLS:Der p 1; MTBLS:Airway epithelium 2023-08
MTBLS1782 MetaboLights Benchmarking non-targeted metabolomics using yeast extract controls Harald Schoeny (Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringerstrasse 38, 1090 Vienna, Austria) solvent blank::Komagataella phaffii::reference compound OMIT:Metabolomics; MTBLS:Lipidomics; MTBLS:Benchmarking dataset; MTBLS:untargeted metabolites; MTBLS:ultra-performance liquid chromatography; MTBLS:High resolution mass spectrometry; MTBLS:Quality control; MTBLS:Pichia Pastoris; MTBLS:LC-MS; MSIO:untargeted metabolite profiling; MTBLS:Yeast; MTBLS:HILIC; MTBLS:RP; MTBLS:Hydrophilic interaction liquid chromatography; MTBLS:reversed phase chromatography; MTBLS:metabolites; MTBLS:lipids 2020-09
MTBLS1765 MetaboLights Osmolality-based normalization enhances statistical discrimination of untargeted metabolomic urine analysis: results from a comparative study Loic Mervant (INRAE) Homo sapiens::blank MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MTBLS:osmolality-based normalization 2023-09
MTBLS1785 MetaboLights Optimizing peak picking and development of a suspect screening tool for rapid annotation of the human chemical exposome from LC- HRMS datasets Jade Chaker (EHESP) sample preparation blank::Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; UBERON:blood plasma; BTO:blood serum; MTBLS:untargeted metabolites; MTBLS:data processing software 2021-01
MTBLS1783 MetaboLights Metabolomics Analysis Reveals Tissue-Specific Metabolite Compositions in Leaf Blade and Traps of Carnivorous Nepenthes Plants Carlos RodrguezLpez (Max Planck Institute for Chemical Ecology) Nepenthes ventricosa x Nepenthes alata MTBLS:tissue specificity; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Lipidomics; MTBLS:pitcher plant 2020-07
MTBLS1792 MetaboLights Bioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays) Sergej Andrejev (EMBL) Eubacterium rectale::Streptococcus salivarius MTBLS:flow injection analysis; MTBLS:untargeted metabolites; NCIT:Microbiome; MTBLS:Direct Infusion Mass Spectrometry; CHEBI:duloxetine 2021-07
MTBLS1794 MetaboLights Untargeted LC-MS metabolomics for the analysis of micro-scaled extracellular metabolites from hepatocytes Romanas Chaleckis (Nagoya City University) Homo sapiens::blank::Reference compound CHMO:liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MTBLS:Micro-scale cell culture medium; CHMO:tandem mass spectrometry 2021-01
MTBLS1791 MetaboLights Bioaccumulation of therapeutic drugs by human gut bacteria: secreted metabolite analysis (FIA-MS) (C.saccharolyticum;E.coli;L.plantarum;L.lactis;S.salivarius assays) Sergej Andrejev (EMBL) Escherichia coli IAI1::Escherichia coli ED1a::Clostridium saccharolyticum::experimental blank::Streptococcus salivarius::Lactococcus lactis subsp. lactis Il1403::solvent blank::Lactobacillus plantarum WCFS1 MS:flow injection analysis; MTBLS:untargeted metabolites; NCIT:Microbiome; CHEBI:duloxetine; CHEBI:roflumilast 2021-07
MTBLS1804 MetaboLights Elucidations on the structures of some putative flavonoids identified in postharvest withered grapes (Vitis vinifera L.) by quadrupole time-of-flight mass spectrometry Mirko DeRosso (CREA-Viticulture & Enology Research Center) Vitis vinifera CHEBI:flavonoids; MTBLS:grape withering; CHMO:tandem mass spectrometry; CHEBI:(+)-dihydromyricetin; MTBLS:taxifolin-pentoside; MTBLS:tetrahydroxyflavanone-hexoside; MTBLS:peonidin-pentoside; MTBLS:dihydromyricetin-hexoside; CHMO:ultra-performance liquid chromatography-mass spectrometry 2021-12
MTBLS1796 MetaboLights A metabolite roadmap of the wood-forming tissue in Populus tremula (GC-MS assay; Wood ring and extraxylary tissue) Ilka Abreu (Dept. Plant Nutrition, Kiel University) Populus tremula EFO:cambium; untargeted metabolomics; ERO:cryosectioning; CHMO:gas chromatography-mass spectrometry; BTO:phloem; BTO:xylem 2020-09
MTBLS1797 MetaboLights A metabolite roadmap of the wood-forming tissue in Populus tremula (UPLC-MS assay; Wood ring and extraxylary tissue) Ilka Abreu (Dept. Plant Nutrition, Kiel University) Populus tremula CHMO:ultra-performance liquid chromatography-mass spectrometry; BTO:cambium; MTBLS:untargeted metabolites; BTO:phloem; BTO:xylem; ERO:cryosectioning 2020-09
MTBLS1812 MetaboLights The Impacts of Sortase A and the 4'-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis Joyce MoralesAparicio (University of Florida) Streptococcus mutans EFO:proteome; NCIT:Lipidomics; NCIT:Streptococcus mutans; untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; vesiculogenesis 2021-10
MTBLS1803 MetaboLights Molecular investigation of Tuscan sweet cherries sampled over three years: gene expression analysis coupled to metabolomics and proteomics Sophie CHARTON (Luxembourg Institute of Science and Technology (LIST)) Prunus avium MTBLS:untargeted metabolites; FOODON:sweet cherry (whole); GAZ:Region of Tuscany; CHEBI:phenylpropanoid; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2021-10
MTBLS1801 MetaboLights Assessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches JamesWilliam Allwood (James Hutton Institute) Avena sativa MTBLS:untargeted metabolites; MTBLS:Plant metabolomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:gas chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MTBLS:nitrogen supplementation; MTBLS:grain quality; CHEBI:beta-D-glucan; NCIT:Lipidomics; fobiowlFOBI:Avenanthramides 2021-04
MTBLS1807 MetaboLights Metabolism links nutrient stress and harmful algal bloom formation Krista Longnecker (Woods Hole Oceanographic Institution) Chaetoceros affinis::Gephyrocapsa oceanica::Heterosigma akashiwo::Prymnesium polylepis MTBLS:untargeted metabolites; MSIO:high performance liquid chromatography; MTBLS:targeted metabolites; CHMO:liquid-solid extraction; CHMO:ultra-performance liquid chromatography-mass spectrometry; ENVO:algal bloom; MTBLS:nutrient stress 2024-02
MTBLS1819 MetaboLights Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata Sven Heiling (Max Planck for chemical Ecology) Nicotiana attenuata CHMO:liquid chromatography-tandem mass spectrometry; MTBLS:untargeted metabolites; CHEBI:diterpene glycoside; UPaUPA:plant chemical defense; IOBC:phytotoxicity 2021-10
MTBLS1821 MetaboLights Wheat growth, applied water use efficiency and flag leaf metabolome under continuous and pulsed deficit irrigation Steffen Neumann (Leibniz Institute of Plant Biochemistry) Triticum aestivum MTBLS:Metabolic fingerprinting; MTBLS:ultra high performance liquid chromatography; MTBLS:flavonoid; MTBLS:benzoxazinoid; MTBLS:Tandem mass spectrometry; MTBLS:Wheat; MTBLS:Drought stress; MTBLS:untargeted metabolites 2020-09
MTBLS1822 MetaboLights Migratory Zooplankton Excreta and its Influence on Prokaryotic Communities Krista Longnecker (Woods Hole Oceanographic Institution) Pleuromamma xiphias::sea water MTBLS:untargeted metabolites; OMIT:Zooplankton; NCBITAXON:seawater metagenome; MTBLS:dissolved organic matter; CHMO:ultra-performance liquid chromatography-mass spectrometry 2020-11
MTBLS1820 MetaboLights Extracellular reef metabolites across the protected Jardines de la Reina, Cuba reef-system Laura Weber (Woods Hole Oceanographic Institution) sea water ENVO:Coral reef sea water; MTBLS:targeted metabolites; MTBLS:untargeted metabolites; MESH:Dissolved Organic Matter; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:Marine Metabolomics; CHEBI:coral metabolite; CHMO:tandem mass spectrometry 2020-11
MTBLS1824 MetaboLights Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease Chung Cho (Seoul National University) Mus musculus OBI:NMR spectroscopy; MTBLS:Obesity; MTBLS:Metabolic syndrome; MTBLS:Gut microbiota 2021-01
MTBLS1831 MetaboLights A metabolite roadmap of the wood-forming tissue in Populus tremula (UPLC-MS assay; Wood fibre and ray cell tissue) Ilka Abreu (Dept. Plant Nutrition, Kiel University) Populus tremula CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; BTO:ray cell; MTBLS:wood developing zone; ERO:cryosectioning 2020-09
MTBLS1825 MetaboLights Imaginal disc growth factor maintains cuticle structure and controls melanization in the spot pattern formation of Bombyx mori Hao Zhihua (Zhejiang University) Bombyx mori MTBLS:Gene Knockout Metabolomics BmIDGF; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:targeted metabolites 2020-09
MTBLS1830 MetaboLights Metabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community; Interaction between the kefir isolates Lactococcus lactis and Acetobacter fabarum (GC-MS) Eleni Kafkia (EMBL, Heidelberg) Bos taurus NCBITAXON:Lactococcus lactis; NCBITAXON:Acetobacter fabarum; NCBITAXON:Acetobacter ghanensis; gas chromatography-mass spectrometry; targeted metabolites 2020-11
MTBLS1833 MetaboLights Oral dysbiosis initiates periodontal disease in experimental kidney disease David Randall (Queen Mary, University of London) Rattus norvegicus EFO:uremia; BTO:saliva; EFO:Periodontitis; CHMO:nuclear magnetic resonance spectroscopy 2025-09
MTBLS1829 MetaboLights Metabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community; Kefir fermentation curve (FIA-MS) Eleni Kafkia (EMBL, Heidelberg) Bos taurus EFO:microbiome; MTBLS:untargeted metabolites; OMIT:Microbial Interactions; MTBLS:fermentation; BTO:milk; MTBLS:flow injection analysis 2020-11
MTBLS1823 MetaboLights Metabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community; Interaction between the kefir isolates Lactococcus lactis and Acetobacter (spent-medium assay, measured untargeted (FIA-qTOF) and targeted (HILIC, LC-MS) Eleni Kafkia (EMBL, Heidelberg) Bos taurus::Reference compound::experimental blank EFO:microbiome; OMIT:Microbial Interactions; MTBLS:fermentation; BTO:milk; MTBLS:flow injection analysis; CHMO:high-performance liquid chromatography-mass spectrometry; MTBLS:targeted metabolites; MTBLS:untargeted metabolites 2020-11
MTBLS1847 MetaboLights Pb Stress and Ectomycorrhizas: Strong Protective Proteomic Responses in Poplar Roots Inoculated with Paxillus involutus Isolate and Characterized by Low Root Colonization Intensity Lukasz Marczak (Institute of Bioorganic Chemistry Polish Academy of Sciences) Populus MTBLS:untargeted metabolites; BTO:ectomycorrhiza; MTBLS:heavy metals; NCIT:Proteomics; MTBLS:Dilution effect; NCIT:Citrate 2022-01
MTBLS1842 MetaboLights Evaluation of significant features discovered from different data acquisition modes in mass spectrometry-based untargeted metabolomics Jian Guo (UBC) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; NCIT:Data-Dependent Acquisition; NCIT:Data-Independent Acquisition 2020-10
MTBLS1846 MetaboLights Antibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria Jiarui Chen (the University of Hong Kong) solvent blank::Reference compound::Homo sapiens MTBLS:microbiome; MTBLS:antibiotics; MTBLS:mycrobiome; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:Gas chromatography mass spectrometry 2020-09
MTBLS1858 MetaboLights The impact of slyA on cell metabolism of Salmonella Typhimurium: a joint study of transcriptomics and metabolomics Sicheng Tian (sichuan university) Salmonella enterica MTBLS:Salmonella enterica subsp. enterica serovar Typhimurium str. LT2; MTBLS:gene function; CHMO:gas chromatography-tandem mass spectrometry; MTBLS:untargeted metabolites 2020-10
MTBLS1839 MetaboLights Coupled Mass-Spectrometry-Based Lipidomics Machine Learning Approach for Early Detection of Clear Cell Renal Cell Carcinoma Malena Manzi (CIBION-CONICET) blank::Homo sapiens NCIT:Lipidomics; NCIT:Clear Cell Renal Cell Carcinoma; CHEBI:biomarker; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; EDAM:Machine learning; STATO:Bayesian least absolute shrinkage and selection operator; NCIT:Support Vector Machine 2020-11
MTBLS1861 MetaboLights Public LC-Orbitrap-MS/MS Spectral Library for Metabolite Identification Prasad Phapale (EMBL) Reference Standards MS:database type spectral library; MTBLS:LC-MS/MS spectral library; NCIT:High Performance Liquid Chromatography Mass Spectrometry; MTBLS:High-resolution mass spec; MTBLS:Orbitrap; MTBLS:fragmentation spectra 2020-09
MTBLS1866 MetaboLights Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2 Marcello Manfredi (UNIUPO, DIMET) Homo sapiens NCBITAXON:severe acute respiratory syndrome coronavirus 2; DOID:COVID-19; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:two-dimensional gas chromatography mass spectrometry; MTBLS:untargeted metabolites; NCIT:Lipidomics; CHEBI:biomarker; CHEBI:fatty acid 2021-11
MTBLS1875 MetaboLights ABHD11/ROLIP maintains the TCA cycle by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex AnaSofia HenriquesdaCosta (Cold Spring Harbor Laboratory) Homo sapiens::experimental blank ERO:stable isotope mass spectrometry; MTBLS:targeted metabolites; MTBLS:lipoic acid; MTBLS:lipid peroxidation; MTBLS:alpha-ketoglutarate; MTBLS:hypoxia inducible factor; MTBLS:alpha-ketoglutarate dehydrogenase complex; MTBLS:ABHD11; MTBLS:2-oxoglutarate; MTBLS:2-oxoglutarate dehydrogenase complex; MTBLS:lipoylation; MTBLS:13C5-glutamine; MTBLS:13C6-glucose; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:CRISPR RNA; CHMO:isotopic labelling 2020-08
MTBLS1873 MetaboLights Cryogenic OrbiSIMS Localizes Semi-Volatile Molecules in Biological Tissues Clare Newell (The Francis Crick Institute) Drosophila melanogaster::Actinidia arguta::Solanum lycopersicum::Pinus nigra::Asparagus officinalis::Homo sapiens::Ribes uva-crispa::reference compound::Malus domestica::Prunus domestica CHMO:secondary ion mass spectrometry imaging; Cryogenic analysis; NCIT:Lipidomics; semi-volatile molecules; CHMO:gas chromatography-mass spectrometry; CHMO:liquid chromatography-mass spectrometry; CHEBI:triglyceride; ENVO:volatile organic compound; MTBLS:untargeted metabolites 2023-03
MTBLS1885 MetaboLights Microbial community functioning during plant litter decomposition Christian Zerfass (FSU Jena) plant litter MTBLS:dissolved organic matter; MTBLS:leaf litter decomposition; EDAM:Microbial ecology; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2024-02
MTBLS1876 MetaboLights A combined direct infusion/reversed phase chromatography – high resolution mass spectrometry workflow for accurate absolute lipid quantification with 13C- internal standards Harald Schoeny (Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringerstrasse 38, 1090 Vienna, Austria) Homo sapiens::Komagataella phaffii::blank::reference compound NCIT:Lipidomics; MTBLS:absolute quantification; epidemiologyontologyowlEO:standardization; MTBLS:flow injection analysis-mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHEBI:isotopic tracer; NCIT:Calibration; MTBLS:targeted metabolites; CHMO:tandem mass spectrometry 2021-07
MTBLS1887 MetaboLights Sequential lipidomic, metabolomic, and proteomic analyses of serum, liver, and heart tissue specimens from peroxisomal biogenesis factor 11α knockout mice Vannuruswamy Garikapati (Justus Liebig University Giessen) Mus musculus NCIT:Lipidomics; MTBLS:untargeted metabolites; NCIT:Proteomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Peroxisome; BAO:gene knockout 2022-02
MTBLS1892 MetaboLights Fruit setting rewires central metabolism via gibberellin cascades Mikiko Takahashi (RIKEN-csrs) Solanum lycopersicum::reference compound MTBLS:metabolic enzyme; MTBLS:Tomatoes; MTBLS:central metabolism; CHEBI:gibberellin; TO:fruit set trait; MTBLS:untargeted metabolites; CO_325:Parthenocarpy; CHMO:gas chromatography-mass spectrometry; CHMO:high-performance liquid chromatography; CHMO:diode array detector 2020-09
MTBLS1890 MetaboLights Metabolite profile of mice hippocampus following Toxoplasma gondii infection Junjun He (CAAS) Mus musculus NCIT:Toxoplasma gondii; CHMO:liquid chromatography-tandem mass spectrometry; MTBLS:untargeted metabolites 2021-01
MTBLS1891 MetaboLights Trans-tissue molecular coordination in high-intensity physical activity YoungMo Kim (Pacific Northwest National Laboratory) Homo sapiens PRIDE:Multi-omics study; MTBLS:Metabolomics; MTBLS:Lipidomics; MTBLS:Proteomics; EFO:exercise 2025-07
MTBLS1898 MetaboLights Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Staphylococcus aureus assays) OveJohanRagnar Gustafsson (University of Melbourne) Staphylococcus aureus Sepsis; NCIT:Antibiotic Resistance; CHMO:liquid chromatography-mass spectrometry; CHMO:gas chromatography-mass spectrometry; MTBLS:untargeted metabolites 2022-08
MTBLS1894 MetaboLights 1H-NMR-Based Analysis for Exploring Knee Synovial Fluid Metabolite Changes after Local Cryotherapy in Knee Arthritis Patients delphine bon (University of Poitiers) Homo sapiens EFO:arthritis; NCIT:Cryotherapy; MTBLS:untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; BTO:knee 2020-11
MTBLS1918 MetaboLights Alterations in the gut microbiota and metabolic profiles coincide with intestinal damage in mice with a bloodborne Candida albicans infection Wanchao Hu (Department of Trauma-Emergency & Critical Care Medicine, Shanghai Fifth People’s Hospital, Fudan University, Shanghai 200240, China) Mus musculus EFO:Candida albicans; EFO:infection; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry 2021-04
MTBLS1903 MetaboLights ProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis EtienneA Thevenot (Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA)) blank::Mus musculus MTBLS:untargeted metabolites; NCIT:Proteomics; MTBLS:R software package; CHMO:ultra-performance liquid chromatography-mass spectrometry; SRAO:Data Integration; EFO:gene knockout; ror:MetaboHUB 2021-09
MTBLS1919 MetaboLights A Python-based pipeline for preprocessing LC-MS data for untargeted metabolomics workflows NICOLAS ZABALEGUI (CIBION-CONICET) Injection control::quality control::Homo sapiens::solvent::reference compound::experimental blank::Solvent Blank::reference sample SWO:Python; MTBLS:data cleaning; MTBLS:preprocessing; MTBLS:untargeted metabolomics; MTBLS:reference materials; MTBLS:data curation; MTBLS:system suitability; UO:drachm; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Workflow 2020-11
MTBLS1905 MetaboLights Regional HNSCC metabolomics reveals widespread changes to one-carbon metabolism and S-adenosylmethionine metabolism across tumour core, tumour edge and adjacent non-tumour tissues Ralf Weber (University of Birmingham) Homo sapiens::blank MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Advanced Head and Neck Squamous Cell Carcinoma; CHEBI:S-adenosyl-L-methionine; MTBLS:Spatial tumour location; MTBLS:Thermo Scientific Dionex Ultimate 3000 UHPLC system; MTBLS:Thermo Scientific Q Exactive Focus; MTBLS:blank; NCBITaxon:Homo sapiens; BTO:squamous cell cancer of the head and neck; MSIO:sample preparation blank; CHMO:experimental sample; pooled quality control sample; MS:untargeted analysis 2026-06
MTBLS1925 MetaboLights EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer Debasis Nayak (The Ohio State University College of Pharmacy) Homo sapiens::blank EFO:pancreatic carcinoma; PR:solute carrier family 22 member 15 (human); PR:solute carrier family 22 member 10; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; NCIT:Epithelial-to-Mesenchymal Transition 2021-10
MTBLS1932 MetaboLights A novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching Chao Feng (Shanghai Municipal Center For Disease Control and Prevention) Rattus norvegicus::reference compound::Reference compound::Homo sapiens::blank EFO:acylcarnitine measurement; NCIT:Data-Independent Acquisition; EDAM:Retention time prediction; CHMO:high-performance liquid chromatography-mass spectrometry; targeted metabolites; CHMO:tandem mass spectrometry 2021-10
MTBLS1906 MetaboLights Characterization of the Human Exposome by a Comprehensive and Quantitative Large-Scale Multianalyte Metabolomics Platform Raul GonzalezDominguez (University of Barcelona) Reference compound MTBLS:targeted metabolites; MTBLS:Exposome; NCBITAXON:Microbiota; NCIT:Food; NCIT:Pollutant; NCIT:Chemical; CHEBI:pharmaceutical; CHMO:ultra-performance liquid chromatography-mass spectrometry 2022-02
MTBLS1935 MetaboLights Mass Spectrometry-Based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism ManuelaRomina Martinefski (Centro de Investigaciones en Bionanociencias (CIBION), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Godoy Cruz 2390, C1425FQD, Ciudad de Buenos Aires, Argentina) Homo sapiens::reference compound::experimental blank MTBLS:untargeted metabolites; MTBLS:in vitro cell culture; MTBLS:RSUME; genesymbolreporthgncid:VHL (human); CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Clear Cell Renal Cell Carcinoma; MTBLS:metabolic fingerprinting 2021-10
MTBLS1952 MetaboLights Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the developing brain Agnes Nadjar (University of Bordeaux) blank::Reference compound::Mus musculus OMIT:Synaptosomes; BTO:hippocampus; CHEBI:omega-3 fatty acid; MTBLS:PUFA deficiency; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-11
MTBLS1956 MetaboLights Cell-to-cell heterogeneity drives host-virus coexistence in a bloom-forming alga Constanze Kuhlisch (Friedrich-Schiller University Jena) blank::Emiliania huxleyi ENVO:algal bloom; OMIT:Host-Pathogen Interactions; MTBLS:Infection Resistance; NCIT:Single Cell Specimen; NCBITaxon:Emiliania huxleyi virus sp.; NCIT:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; CHMO:high-resolution mass spectrometry; MTBLS:untargeted metabolites 2024-01
MTBLS1963 MetaboLights The genetic origin of evolidine, the first cyclopeptide discovered in plants, and related orbitides Mark Fisher (The University of Western Australia) Reference compound::Melicope xanthoxyloides CHMO:tandem mass spectrometry; CHMO:high-performance liquid chromatography-mass spectrometry; MTBLS:targeted metabolites; CHEBI:cyclic peptide; OMIT:Peptide Biosynthesis; EDAM:Plant biology; MTBLS:orbitide 2020-10
MTBLS1955 MetaboLights Comparative Lipidomics of Different Yeast Species Associated to Drosophila suzukii Flavia Bianchi (Laimburg Research Centre) Saccharomyces cerevisiae::Saccharomycopsis vini::Candida::Pichia terricola::Pooled Sample::Metschnikowia pulcherrima::experimental blank::Hanseniaspora uvarum MTBLS:yeast strains; MTBLS:lipidomics; MTBLS:untargeted metabolites; CHMO:Liquid chromatography mass spectrometry 2021-02
MTBLS1965 MetaboLights Metabolic fingerprinting reveals roles of <i>Arabidopsis thaliana</i> BGLU1, BGLU3, and BGLU4 in glycosylation of various flavonoids Rabea Schweiger (Department of Chemical Ecology, Bielefeld University) Arabidopsis thaliana MTBLS:Arabidopsis thaliana; NCBITaxon:Brassicaceae; CHEBI:flavonoids; NCIT:Glycosylation; NCIT:Glycosyltransferase; MTBLS:BGLU; MTBLS:Metabolic fingerprinting 2025-02
MTBLS1967 MetaboLights IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (FA_HILICZ) Mioara Larion (Neuro-Oncology Branch/ National Cancer Institute) Experimental control::Experimental blank::Homo sapiens CHMO:Raman microscope; MTBLS:Lipidomics; GO:organelle 2020-11
MTBLS1964 MetaboLights Insights into Metabolic Changes Caused by the Trichoderma virens-Maize Root Interaction Rabea Schweiger (Department of Chemical Ecology, Bielefeld University) Zea mays::Trichoderma virens Gv29-8 CHEBI:benzoxazine; NCBITAXON:fungal endophyte; CHEBI:flavonoids; MTBLS:Fungus-plant interactions; NCIT:Genomics; MTBLS:Plant antifungal responses; PECO:fungal plant exposure; CHEBI:secondary metabolite; BTO:secretion; NCBITAXON:Trichoderma; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MTBLS:untargeted metabolites 2021-07
MTBLS1969 MetaboLights ECM deposition is driven by caveolin1-dependent regulation of exosomal biogenesis and cargo sorting Jess Balsinde (CSIC) Mus musculus EFO:metabolomic profiling; ORDO:caveolin 1; MTBLS:untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; NCIT:Extracellular Matrix; MTBLS:cancer; EFO:gene knock out 2020-10
MTBLS1960 MetaboLights Molecular Basis Underlying Common Cutworm Resistance of the Primitive Soybean Landrace Peking Ryu Nakata (Kyoto University of Advanced Science) Glycine max::pure substance::purified material::Enrei::Blank NCIT:soybean; MTBLS:Peking; MTBLS:common cutworm; MTBLS:resistance; MTBLS:chromosome segment substitution lines (CSSLs) 2020-11
MTBLS1972 MetaboLights Comprehensive lipid analysis of green Arabica coffee beans by LC-HRMS/MS Rafael Garrett (Metabolomics Laboratory, Institute of Chemistry, Federal University of Rio de Janeiro) blank::Coffea arabica CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Coffee; CHMO:orbitrap; MS:electrospray ionization; MTBLS:Lipidomics; CHMO:tandem mass spectrometry; MTBLS:untargeted metabolites 2021-11
MTBLS1973 MetaboLights IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (CSHNeg) Mioara Larion (Neuro-Oncology Branch/ National Cancer Institute) Experimental control::Homo sapiens::experimental blank MTBLS:lipid profiling; CHMO:Raman microscope; GO:organelle; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MTBLS:Lipidomics 2020-11
MTBLS1968 MetaboLights Plot diversity differentially affects the chemical composition of leaves, roots and root exudates in four subtropical tree species Steffen Neumann (Leibniz Institute of Plant Biochemistry) Schima superba::Daphniphyllum oldhamii::blank::Cinnamomum camphora::reference compound::Quercus glauca::Quercus glauca;Schima superba;Daphniphyllum oldhamii,Cinnamomum camphora MTBLS:chemical diversity; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:plant-plant interaction; CHEBI:secondary metabolite; MTBLS:tree interaction; MTBLS:tropical forest interactions; MTBLS:untargeted metabolites 2021-08
MTBLS1974 MetaboLights IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (CSHpos) Mioara Larion (Neuro-Oncology Branch/ National Cancer Institute) Homo sapiens::experimental blank::Experimental control CHMO:Raman microscope; MTBLS:Lipidomics; GO:organelle; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2020-11
MTBLS1977 MetaboLights ECM deposition is driven by caveolin1-dependent regulation of exosomal biogenesis and cargo sorting Alessia Ferrarini (CNIC) Mus musculus::experimental blank NCIT:Extracellular Matrix; MTBLS:targeted metabolites; NCIT:Cholesterol; OMIT:Exosomes; MTBLS:liquid chromatography-tandem mass spectrometry; ORDO:caveolin 1; MTBLS:cancer; EFO:gene knock out 2020-10
MTBLS1983 MetaboLights Generation of a chromosome-scale genome assembly of the insect-repellent terpenoid-producing Lamiaceae species, Callicarpa americana Emily Lanier (Michigan State University) Nicotiana benthamiana NCBITAXON:Lamiaceae; GO:kolavenyl diphosphate synthase activity; CHEBI:diterpene; MTBLS:targeted metabolites; NCBITAXON:Callicarpa americana; CHMO:gas chromatography-mass spectrometry; CHEBI:insect repellent; MTBLS:terpene synthase 2020-12
MTBLS1978 MetaboLights Metabolic profiling of Candida clinical isolates of different species and infection sources Luca Laghi (Bologna University) Candida glabrata::Candida parapsilosis::Candida tropicalis::Candida albicans MTBLS:untargeted metabolites; NCBITaxon:Candida; CHMO:1H nuclear magnetic resonance spectroscopy; NCIT:Lipidomics; NCIT:Fungal Infection; NCIT:Proteomics 2024-07
MTBLS1980 MetaboLights Chemotaxis shapes the microscale organization of the ocean’s microbiome JeanBaptiste Raina (University of Technology Sydney) Ditylum::Prymnesium::Alexandrium::Amphidinium::reference compound::Dunaliella::Alexandrium; Amphidinium; Chaetoceros; Ditylum; Dunaliella; Emiliania; Phaeodactylum; Prymnesium; Synechococcus; Thalassiosira::Emiliania::Synechococcus::Thalassiosira::Chaetoceros::blank::Phaeodactylum MTBLS:untargeted metabolites; CHMO:gas chromatography-mass spectrometry; ENVO:ocean; NCIT:Microbiome; MTBLS:Phytoplankton; MTBLS:dissolved organic matter; NCIT:Metagenomics; GO:chemotaxis 2022-02
MTBLS2007 MetaboLights Model-guided development of evolutionarily stable yeast chassis for dicarboxylic acids production Filipa Pereira (EMBL) Saccharomyces cerevisiae MTBLS:adaptive laboratory evolution; MTBLS:targeted metabolites; NCIT:Proteomics; EFO:transcription profiling by high throughput sequencing; MTBLS:genome-scale modeling; CHEBI:dicarboxylic acids and O-substituted derivatives; NCIT:Genetic Engineering; CHMO:gas chromatography-mass spectrometry 2021-07
MTBLS1987 MetaboLights Kynurenic acid underlies sex-specific immune responses to COVID-19 Yuping Cai (Yale University) Homo sapiens DOID:COVID-19; MTBLS:Immune responses; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2020-09
MTBLS2014 MetaboLights Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection Luke Whiley (Murdoch University) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:targeted metabolites; DOID:COVID-19; MS:selected reaction monitoring 2021-01
MTBLS1990 MetaboLights Metabolic profiling of maternal serum of women at high-risk of spontaneous preterm birth using NMR and MGWAS approach MarieMargaret Phelan (University of Liverpool) Homo sapiens CHMO:nuclear magnetic resonance spectroscopy; MTBLS:mGAWS; MTBLS:probabilistic neural network; EFO:premature birth; MTBLS:untargeted metabolites; CHEBI:biomarker 2023-05
MTBLS2015 MetaboLights Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays) OveJohanRagnar Gustafsson (University of Melbourne) Escherichia coli HP:Sepsis; NCIT:Antibiotic Resistance; CHMO:liquid chromatography-mass spectrometry; CHMO:gas chromatography-mass spectrometry; MTBLS:untargeted metabolites 2022-08
MTBLS2017 MetaboLights Umbilical cord blood metabolome differs in relation to delivery mode, birth order and sex, maternal diet and possibly future allergy development in rural children Alastair Ross (AgResearch) Homo sapiens MTBLS:gas chromatography-mass spectrometry; EFO:allergy; UBERON:umbilical cord blood; MTBLS:untargeted metabolites 2020-12
MTBLS2016 MetaboLights Comparison of lipidome profiles of Caenorhabditis elegans—results from an inter-laboratory ring trial Michael Witting (Helmholtz Zentrum München) Caenorhabditis elegans MTBLS:untargeted metabolites; NCIT:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Interlaboratory; MTBLS:ring trial 2022-02
MTBLS1991 MetaboLights A molecular index for biological age identified from the metabolome and senescence-associated secretome in humans. Aditi Gurkar (University of Pittsburgh) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; MTBLS:senescence-associated secretome; NCIT:Cell Aging; NCIT:Aging 2024-01
MTBLS2026 MetaboLights Online Headspace-Solid Phase Microextraction-Gas Chromatography-Mass Spectrometry-based untargeted volatile metabolomics for studying emerging complex biopesticides: A proof of concept Hikmat Ghosson (Michelin) soil::blank MTBLS:Untargeted Metabolomics; MESH:Biological Control Agents; CHMO:headspace solid-phase micro-extraction; CHEBI:volatile organic compound; MTBLS:Gas Chromatography-Mass Spectrometry 2021-01
MTBLS2042 MetaboLights Two UGT84A Family Glycosyltransferases Regulate Phenol, Flavonoid, and Tannin Metabolism in Juglans regia (English Walnut) Houston Saxe (University of California, Davis) Nicotiana tabacum MTBLS:untargeted metabolites; CHMO:gas chromatography time-of-flight mass spectrometry; GO:glucosyltransferase activity; CHEBI:hydrolysable tannin; MTBLS:UGT84A; CHEBI:gallic acid; NCBITAXON:Juglans regia; MTBLS:phenol metabolism; NCIT:Transcriptomics; MTBLS:WCMC 2022-10
MTBLS2040 MetaboLights Symptomatology and Serum Nuclear Magnetic Resonance Metabolomics; Do They Predict Endometriosis in Fertile Women Undergoing Laparoscopic Sterilisation? A Prospective Cross-sectional Study MarieMargaret Phelan (University of Liverpool) Homo sapiens EFO:endometriosis; NCIT:Diagnosis; NCIT:Incidence; CHMO:nuclear magnetic resonance spectroscopy; MTBLS:untargeted metabolites; SNOMED:Laparoscopic female sterilization (procedure); CHEBI:biomarker 2023-05
MTBLS2021 MetaboLights Integration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance Christian Jaeger (LUXEMBOURG CENTRE FOR SYSTEMS BIOMEDICINE) Reference compound::microbial community::Retention Index Reference Mixture::Pooled Sample::solvent blank ENVO:activated sludge; MTBLS:Lipid accumlation; MTBLS:Lipidomics; MTBLS:time series design; MTBLS:untargeted metabolites; CHMO:Gas chromatography mass spectrometry; NCIT:Disturbance 2021-04
MTBLS2028 MetaboLights Distinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones Noriko Nakamura (NCTR/FDA) Rattus norvegicus NCIT:Chronic Inflammation; CHEBI:estradiol; CHEBI:testosterone; NCIT:Lipidomics; targeted metabolites; flow injection analysis-mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:Biocrates Absolute IDQp180 kit 2020-11
MTBLS2053 MetaboLights The Relative Content and Distribution of Absorbed Volatile Organic Compounds in Rats Administered Asari Radix et Rhizoma Are Different between Powder- and Decoction-Treated Groups Guangxue Liu (Health Science Center, Peking University) Rattus norvegicus CHEBI:volatile organic compound; MTBLS:untargeted metabolites; CHMO:headspace solid-phase micro-extraction; CHMO:gas chromatography-mass spectrometry; MTBLS:Asari Radix et Rhizoma; MTBLS:chinese herbal medicine 2021-02
MTBLS2044 MetaboLights LC-HRMS-Driven Computational Toolbox to Assess Extraction Protocols Dedicated to Untargeted Analysis: How to Ease Analyzing Pesticide-Contaminated Soils? Hikmat Ghosson (Michelin) soil::Blank Extraction::blank::reference compound NCIT:Extraction; NCIT:Liquid Chromatography; MTBLS:High Resolution Mass Spectrometry; NCIT:Method Development; MTBLS:Data Analysis; operation:Chemometrics; MTBLS:Soil; OMIT:Pesticides 2025-01
MTBLS2075 MetaboLights Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers Shane Ellis (University of Wollongong) Mus musculus MTBLS:isotope labelling; OMIT:Lipids; MTBLS:imaging mass spectrometry; MTBLS:lung; CHEBI:surfactant; MTBLS:phosphatidylcholine 2020-10
MTBLS2074 MetaboLights Symbiotic bacteria-derived organic acids protect Delia antiqua larvae from entomopathogenic fungal infection Fangyuan Zhou (Ecology Institute, Shandong Academy of Sciences) media blank::Sphingobacterium faecium::Enterobacter ludwigii::Citrobacter freundii;Enterobacter ludwigii;Pseudomonas protegens;Serratia plymuthica;Stenotrophomonas maltophilia;Sphingobacterium faecium;Klebsiella oxytoca::Citrobacter freundii::Stenotrophomonas maltophilia::Pseudomonas protegens::Klebsiella oxytoca::Serratia plymuthica OMIT:Symbiosis; NCIT:Insect; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MTBLS:colonization resistance; MTBLS:defensive association; GO:mutualism 2020-11
MTBLS2060 MetaboLights Prediction of complex phenotypes using the Drosophila melanogaster metabolome Anders Malmendal (Roskilde University) Drosophila melanogaster CHMO:nuclear magnetic resonance spectroscopy; EFO:phenotype; MTBLS:untargeted metabolites; MTBLS:Drosophila Genetic Reference Panel 2021-08
MTBLS2052 MetaboLights Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease Munsoor Hanifa (Aalborg University Hospital) Rattus rattus EFO:chronic kidney disease; XCO:nephrectomy; SNOMEDCT:Wistar rat; CHMO:nuclear magnetic resonance spectroscopy; MTBLS:targeted metabolites; CHMO:two-dimensional nuclear magnetic resonance spectrum 2020-11
MTBLS2080 MetaboLights Enterococcus faecalis readily adapts membrane phospholipid composition to environmental and genetic perturbation Brittni Woodall (University of Tennessee Knoxville ) Enterococcus faecalis NCIT:Lipidomics; CHMO:ultra high performance liquid chromatography; CHEBI:phospholipid; CHEBI:cardiolipin; MTBLS:untargeted metabolites; MTBLS:mprF2; MTBLS:Lysyl-phosphatidylglycerol; CHEBI:daptomycin 2021-05
MTBLS2081 MetaboLights Untargeted metabolomic investigate milk and ruminal fluid of Holstein cows supplemented with Perilla frutescens leaf Bing Wang (China Agricultural University) Bos taurus UPaUPA:pyrimidine metabolism; BTO:milk; NCIT:Rumen; MTBLS:Metabolomics 2020-11
MTBLS2087 MetaboLights Clostridium butyricum MIYAIRI 588-induced protectin D1 has an anti-inflammatory effect on antibiotic-induced intestinal disorder Tadashi Ariyoshi (MIYARISAN PHARMACEUTICAL CO., LTD.) Mus musculus::reference compound NCBITAXON:Clostridium butyricum; TXPO:lipid mediator; CHEBI:protectin D1; PR:free fatty acid receptor 4; IDOMAL:interleukin 4; MTBLS:liquid chromatography-tandem mass spectrometry 2020-10
MTBLS2088 MetaboLights Determination and comparison of SCFAs in serum and colon content samples: Alzheimer's disease rat as a case study (SCFA serum and colon content determination) Linxiu Guo (Shenzhen Institute of Drug Control) Rattus rattus CHEBI:short-chain fatty acid; EFO:Alzheimer's disease; CHMO:derivatisation; MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2020-11
MTBLS2096 MetaboLights Differential alteration of plant functions by homologous fungal candidate effectors KarenCristineGoncalves Santos (Universite du Quebec a Trois-Rivieres) Arabidopsis thaliana MTBLS:Metabolomics; EFO:transcriptome; NCBITAXON:Arabidopsis thaliana; BAO:LTQ-Orbitrap Velos (Thermo Scientific); CHMO:Fourier transform ion cyclotron resonance mass spectrometry 2020-12
MTBLS2104 MetaboLights Physiological extremes of the human blood metabolome: A metabolomics analysis of highly glycolytic, oxidative, and anabolic athletes Werner RoemischMargl (Helmholtz Zentrum Muenchen) blank::Homo sapiens::reference compound MTBLS:targeted metabolites; MTBLS:Biocrates Absolute IDQp180 kit; NCIT:Exercise; NCIT:Physiology; CHEBI:biomarker; NCIT:Energy Metabolism Process; GSSO:athlete; NCIT:Phenotype 2022-02
MTBLS2085 MetaboLights NQO1 protects obese mice through improvements in glucose and lipid metabolism. Miguel Aon (National Institute on Aging, National Institutes of Health) Mus musculus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; EFO:diabetes mellitus; EFO:obesity 2024-05
MTBLS2105 MetaboLights Untargeted metabolomics reveals species-specific metabolite production and shared nutrient consumption by Pseudomonas aeruginosa and Staphylococcus aureus Laura Dunphy (Department of Biomedical Engineering/University of Virginia) Pseudomonas aeruginosa;Staphylococcus aureus::blank::Pseudomonas aeruginosa::Staphylococcus aureus CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; AGRO:monoculture; NCIT:Cystic Fibrosis; CHMO:tandem mass spectrometry 2021-05
MTBLS2108 MetaboLights Human age-declined saliva metabolic markers determined by LC-MS Takayuki Teruya (OIST) Homo sapiens NCIT:Aging; CHMO:high performance liquid chromatography-tandem mass spectrometry; MTBLS:untargeted metabolites; CHEBI:biomarker 2021-02
MTBLS2109 MetaboLights Whole blood metabolomics of dementia patients reveal classes of disease-linked metabolites Takayuki Teruya (OIST) Homo sapiens EFO:Alzheimer's disease; MTBLS:untargeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Alteration Of Cognitive Function; CHMO:tandem mass spectrometry 2021-07
MTBLS2119 MetaboLights Uncovering the Complexity of the Yeast Lipidome by Means of nLC/NSI-MS/MS Stefanie Rubenzucker (University of Vienna) Saccharomyces cerevisiae NCIT:Lipidomics; CHMO:nanoflow liquid chromatography-tandem mass spectrometry; MTBLS:untargeted metabolites 2021-01
MTBLS2111 MetaboLights Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics and Lipidomics Identify Biomarkers for Efficacy Evaluation of Mesalazine in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model liu kun (South China University of Technology) Mus musculus CHEBI:mesalamine; EFO:ulcerative colitis; CHEBI:biomarker; MTBLS:untargeted metabolites; NCIT:Lipidomics; CHMO:ultra-performance liquid chromatography-mass spectrometry 2022-10
MTBLS2130 MetaboLights Metabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS SylviaKarin Neef ( Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology (IKP)) Blank::Homo sapiens::reference compound NCIT:Lipidomics; OMIT:Organoids; MTBLS:colorectal cancer; MTBLS:untargeted metabolites 2021-10
MTBLS2131 MetaboLights A multi-omics approach to study peroxisome proliferator-activated receptor mediated regulation of lipid metabolism in Atlantic cod (Gadus morhua) Marta Eide (University of Bergen) blank::Reference compound::Gadus morhua MTBLS:untargeted metabolites; NCIT:Fish; NCIT:Transcriptomics; NCIT:Lipidomics; PRIDE:Multi-omics study; IMR:PPAR; ATOL:lipid metabolism; NCIT:Environmental Toxicology; NCIT:Proteomics; MTBLS:flow injection analysis-mass spectrometry 2022-02
MTBLS2137 MetaboLights Plasma 1H-NMR metabolic and amino acid profiles of newborn piglets from two lines divergently selected for residual feed intake Galle Lefort (INRAE) Sus scrofa MTBLS:untargeted metabolites; CHMO:nuclear magnetic resonance spectroscopy; MTBLS:targeted metabolites; MTBLS:automatic quantification; MTBLS:Proof of Concept Study; ATOL:residual feed intake 2023-02
MTBLS2154 MetaboLights Clovamide, a hydroxycinnamic acid amide, is a resistance factor against Phytophthora spp. in Theobroma cacao Benjamin Knollenberg (Pennsylvania State University) Theobroma cacao::blank EDAM:Metabolomics; BAO:plant; MESH:Phytophthora; BIOMODELS:secondary metabolite; CHMO:ultra-performance liquid chromatography-mass spectrometry 2020-12
MTBLS2145 MetaboLights Metabolic Dynamics of In Vitro CD8+ T Cell Activation Joerg Buescher (MPI-IE) blank::Mus musculus MTBLS:flow injection analysis-mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; CHMO:tandem mass spectrometry; CL:T cell; BAO:time course profile; NCIT:Lipidomics; MTBLS:LC-MS label-free quantitation analysis 2021-06
MTBLS2148 MetaboLights Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk Xu Sha (FuDan University) Homo sapiens EFO:Spontaneous abortion; CHMO:nuclear magnetic resonance spectroscopy; CHMO:two-dimensional 1H nuclear magnetic resonance spectroscopy; MTBLS:targeted metabolites; CHEBI:succinate 2021-10
MTBLS2146 MetaboLights Determination and comparison of SCFAs in serum and colon content samples: Alzheimer's disease rat as a case study (Method validation) Linxiu Guo (Shenzhen Institute of Drug Control) Rattus rattus CHEBI:short-chain fatty acid; EFO:Alzheimer's disease; CHMO:derivatisation; MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Bioanalytical Validation Method 2020-11
MTBLS2159 MetaboLights Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques Sanne Verberk (Amsterdam UMC) Mus musculus MTBLS:ATP-Citrate lyase; CHMO:ultra-performance liquid chromatography-mass spectrometry; NCIT:Inflammation; MTBLS:untargeted metabolites 2021-03
MTBLS2166 MetaboLights Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis Mariana SilvadosSantos (The Francis Crick Institute) Hordeum vulgare::reference compound mix::blank::Glossina morsitans morsitans MTBLS:hematophagous insects; OMIT:4-Hydroxyphenylpyruvate Dioxygenase; NCBITAXON:ant, tsetse, mealybug, aphid, etc. endosymbionts; NCIT:African Trypanosomiasis; MTBLS:untargeted metabolites; GO:tyrosine catabolic process; CHEBI:nitisinone; CHMO:Liquid chromatography mass spectrometry; CHMO:tandem mass spectrometry 2021-10
MTBLS2171 MetaboLights Maternal regulation of biliary disease in neonates via gut microbial metabolites Li Yang (Cincinnati Children's Hospital Medical Center) Mus musculus NCIT:Biliary Atresia; NCIT:Microbiome; MTBLS:untargeted metabolites; CHEBI:butyrate; CHEBI:glutamine; MTBLS:nuclear magnetic resonance spectroscopy; NCIT:Newborn; NCIT:Rotavirus 2022-01
MTBLS2150 MetaboLights Hyperhomocysteinemia-related serum metabolome alterations not normalized by short-term folic acid treatment Aneesh Kumar (Rajiv Gandhi Centre for Biotechnology) Homo sapiens CHEBI:folate; NCIT:Hyperhomocysteinemia; CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites 2022-02
MTBLS2199 MetaboLights Sponges With Microbial Symbionts Transform Dissolved Organic Matter and Take Up Organohalides (2018 collection assay) Lauren Olinger (University of North Carolina Wilmington) Verongula reiswigi::Mycale laxissima::Xestospongia muta::blank::Agelas tubulata::Niphates digitalis::Callyspongia vaginalis NCBITAXON:Porifera; ENVO:marine coral reef fore reef; MTBLS:untargeted metabolites; MTBLS:dissolved organic matter; CHEBI:organohalogen compound; CHMO:ultra-performance liquid chromatography-mass spectrometry 2022-03
MTBLS2207 MetaboLights Improving Metabolite Identification with DecoID for Database-Assisted Deconvolution of Metabolomic MS/MS Spectra Ethan Stancliffe (Washington University in St. Louis) Escherichia coli::Reference compound::Homo sapiens::Komagataella pastoris MTBLS:untargeted metabolites; NCIT:Data-Independent Acquisition; NCIT:Data-Dependent Acquisition; CHMO:tandem mass spectrometry; NCIT:Software Development; CHMO:ultra-performance liquid chromatography-mass spectrometry 2021-04
MTBLS2200 MetaboLights Sponges With Microbial Symbionts Transform Dissolved Organic Matter and Take Up Organohalides (2019 collection assay) Lauren Olinger (University of North Carolina Wilmington) Xestospongia muta::blank::Agelas tubulata Porifera; marine coral reef fore reef; MTBLS:untargeted metabolites; MTBLS:dissolved organic matter; organohalogen compound; ultra-performance liquid chromatography-mass spectrometry 2022-03
MTBLS2187 MetaboLights Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health Francesco Marabita (Karolinksa Institutet) Homo sapiens SRAO:Data Integration; MTBLS:lifestyle changes; OMIABIS:longitudinal study design; MTBLS:precision health; OMIT:Precision Medicine; MTBLS:untargeted metabolites; CHMO:gas chromatography time-of-flight mass spectrometry; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2021-09
MTBLS2205 MetaboLights Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import Ulrich Goldmann (CeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences) Homo sapiens::Reference compound GO:mitochondrial NAD transmembrane transport; MTBLS:targeted metabolites; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; OBI:analyte assay; PR:solute carrier family 25 member 51 2021-03
MTBLS2217 MetaboLights Adaptive laboratory evolution of microbial co-cultures for improved metabolite secretion Dimitrios Konstantinidis (EMBL) Saccharomyces cerevisiae::reference compound::Lactobacillus plantarum MTBLS:Adaptive evolution; GO:mutualism; MTBLS:vitamin production; MTBLS:lactic acid bacteria; MTBLS:targeted metabolites; CHMO:gas chromatography-mass spectrometry; CHMO:liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2021-07
MTBLS2188 MetaboLights Exploring the Glucose Fluxotype of the E. coli y-ome Using High-Resolution Fluxomics Cecilia Berges (MetaboHub - MetaToul) Escherichia coli EDAM:Fluxomics; NCIT:High Throughput Screening; NCIT:Bacteria; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:nuclear magnetic resonance spectroscopy; MTBLS:targeted metabolites; MTBLS:high-resolution fluxotyping; MTBLS:y-ome phenotyping; ror:MetaboHUB 2021-05
MTBLS2218 MetaboLights Liquid Chromatography-High-Resolution Mass Spectrometry-Based In Vitro Toxicometabolomics of the Synthetic Cathinones 4-MPD and 4-MEAP in Pooled Human Liver Microsomes SaschaK Manier (Saarland University) Homo sapiens MTBLS:untargeted metabolites; CHMO:high-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; NCIT:Toxicology; MTBLS:Synthetic cathinone 2023-11
MTBLS2224 MetaboLights Sex-specific metabolic shifts in plasma of COVID-19 patients after cure Hong Zheng (Wenzhou Medical University) Homo sapiens NCIT:COVID-19 Terminology; MTBLS:untargeted metabolites; MTBLS:Sex Difference; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:gas chromatography-mass spectrometry; CHEBI:biomarker; NCIT:Severity 2022-01
MTBLS2235 MetaboLights Operation of a TCA cycle subnetwork in the mammalian nucleus Eleni Kafkia (EMBL, Heidelberg) HeLa cell NCIT:Nucleus; NCIT:Metabolic Pathway; MSIO:stable isotope resolved metabolomics study; CHMO:gas chromatography-mass spectrometry; MTBLS:targeted metabolites; NCIT:The Citric Acid Cycle 2022-06
MTBLS2240 MetaboLights An Evolutionarily Conserved Metabolite Inhibits Biofilm Formation in Escherichia coli K-12 Steffen Neumann (Leibniz Institute of Plant Biochemistry) Escherichia coli str. K-12 substr. MG1655::blank::Reference compound MTBLS:targeted metabolites; MTBLS:central energy metabolism; GO:biofilm formation 2024-11
MTBLS2215 MetaboLights Metabolomics Insights in Early Childhood Caries Kimon Divaris (University of North Carolina-Chapel Hill) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; MTBLS:biofilm; MTBLS:children; MTBLS:risk assessment; NCIT:Caries; EFO:microbiome; OMIT:Machine Learning; NCIT:Dental; IOBC:metabolon; CHMO:tandem mass spectrometry 2021-01
MTBLS2239 MetaboLights Estimating essential phenotypic and molecular traits from integrative biodiversity data Kristian Peters (IPB Halle) Riccia beyrichiana::Riccia cavernosa::Mannia fragrans::Riccia bifurca::Reboulia hemisphaerica::Riccia ciliifera::Riccia sorocarpa::Riccia gothica::Riccia subbifurca::Asterella gracilis::Athalamia hyalina::Riccia canaliculata::Riccia huebeneriana::Riccia gougetiana NCIT:Phenotype; NCBITaxon:bryophyte; NCBITaxon:Bryophyta environmental sample; NCBITaxon:Marchantiophyta; EDAM:Biodiversity; NCBITaxon:Marchantiales; NCBITaxon:Ricciaceae; NCBITaxon:Riccia; NCBITaxon:Cleveaceae; NCBITaxon:Athalamia; NCBITaxon:Aytoniaceae; NCBITaxon:Mannia; NCBITaxon:Asterella; NCBITaxon:Reboulia; NCIT:Taxonomy; IOBC:chemotaxonomy; c:Plant Ecology; MTBLS:untargeted metabolites; ENVO:soil biocrust; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry 2024-06
MTBLS2243 MetaboLights A metabolic dependency of EBV can be targeted to hinder B cell transformation Glenn Bantug (University of Basel, Department of Biomedicine) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; OBI:Epstein Barr virus transformed B cell 2024-04
MTBLS2247 MetaboLights Susceptibility to febrile malaria is associated with an inflammatory gut microbiome Nathan Schmidt (Indiana University School of Medicine) Homo sapiens CHMO:ultra-performance liquid chromatography-mass spectrometry; MTBLS:untargeted metabolites; IOBC:metabolon; CHMO:tandem mass spectrometry; OHMI:human gut microbiome; NCIT:Mali; EFO:malaria 2024-09
MTBLS2262 MetaboLights Global analysis of plasma lipidomics reveals altered lipid signatures in patients with osteonecrosis of the femoral head Jihan Wang (Northwestern Polytechnical University) blank::Homo sapiens NCIT:Lipidomics; NCIT:Osteonecrosis of the Femoral Head; CHEBI:biomarker; CHMO:ultra-performance liquid chromatography-mass spectrometry; CHMO:tandem mass spectrometry; MTBLS:untargeted metabolites; MTBLS:Novogene 2021-07

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